Zobrazeno 1 - 10
of 32
pro vyhledávání: '"M D Clayman"'
Autor:
H Shiraga, W Min, C H Terrell, Craig T. Przysiecki, John W. Foreman, D Miner, M D Clayman, Joseph R. Sherbotie, W J VanDusen, Eric G. Neilson
Publikováno v:
Proceedings of the National Academy of Sciences. 89:426-430
The majority of human urinary stones are primarily composed of calcium salts. Although normal urine is frequently supersaturated with respect to calcium oxalate, most humans do not form stones. Inhibitors are among the multiple factors that may influ
Autor:
Carolyn J. Kelly, William H. Hines, Thomas P. Haverty, Nancy E. Cooke, M D Clayman, Mae Jane Sun, Eric G. Neilson
Publikováno v:
Proceedings of the National Academy of Sciences. 88:2006-2010
Anti-tubular basement membrane (alpha TBM) disease is a form of primary interstitial nephritis mediated by autoimmune T cells and alpha TBM antibodies. In mice and humans the nephritogenic immune response is directed to a glycoprotein (3M-1) found al
Publikováno v:
Ciba Foundation Symposium 129-Autoimmunity and Autoimmune Disease ISBN: 9780470513484
Ciba Foundation Symposium 129-Autoimmunity and Autoimmune Disease
Ciba Foundation Symposium 129-Autoimmunity and Autoimmune Disease
The therapeutic application of immune regulation and suppressor T cells to the control and modulation of autoimmune disease is an area of growing experimental interest. Our group has been studying experimental interstitial nephritis, both to better u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cbf8410dded7e4aee72e83f7fb6fb5b6
https://doi.org/10.1002/9780470513484.ch6
https://doi.org/10.1002/9780470513484.ch6
Publikováno v:
The American journal of the medical sciences. 305(1)
Severe neurotoxicity and acute renal failure developed in a patient with newly diagnosed AIDS while receiving high-dosage intravenous acyclovir for disseminated herpes zoster. Hemodialysis resulted in a rapid resolution of neurologic symptoms and was
Publikováno v:
The Journal of Immunology. 136:903-907
We utilized a model of experimental interstitial nephritis induced by renal tubular antigen in complete Freund's adjuvant to examine a mechanism of immunologic tolerance produced by priming immunization with tubular antigen in incomplete Freund's adj
Publikováno v:
International Archives of Allergy and Immunology. 87:329-333
Antibodies eluted from kidneys by traditional methods of pH shift have been used as reagents in a wide variety of experimental analyses without knowledge of whether their ligand affinity influenced their removal from parenchymal tissue. In the curren
Autor:
Eric G. Neilson, Robert Alper, L Michaud, Nicholas A. Kefalides, Richard Mann, M D Clayman, Antonio Martinez-Hernandez
Publikováno v:
The Journal of Experimental Medicine
Using monoclonal antibody affinity chromatography, we isolated a 48,000 mol wt, glucose-rich glycoprotein (3M-1) from collagenase-solubilized rabbit renal tubular basement membrane (SRTA). The purified 3M-1 protein is noncollagenous, and is capable o
Publikováno v:
The Journal of Immunology. 133:2560-2565
Mice of the kdkd strain predictably develop a spontaneous tubulointerstitial nephritis after 8 wk of life. In this report we have examined several aspects of the nephritogenic immune response that seemed potentially relevant to the expression of this
Autor:
Debra Cohn, David B. Agus, Carolyn J. Kelly, L Michaud, M D Clayman, Richard Mann, Eric G. Neilson
Publikováno v:
Kidney International. 29(3):635-640
The effects of daily cyclophosphamide administration on the development and extent of primary experimental interstitial nephritis in rats. We examined the effects of daily cyclophosphamide administration on the development and extent of tubulointerst
Publikováno v:
The Journal of Experimental Medicine
Experimental anti-tubular basement membrane (anti-TBM) disease is an autoimmune interstitial nephritis elicited in susceptible rodents after immunization with renal tubular antigen. The nephritogenic antigen in the immunizing preparation is 3M-1, a 4