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pro vyhledávání: '"M D, Percival"'
We present new approaches to reservoir modeling and flow simulation that dispose of the pillar-grid concept that has persisted since reservoir simulation began. This results in significant improvements to the representation of multiscale geologic het
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2127::c0d3737d637d5cce1af19ef89cf7cde2
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3165874
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3165874
Publikováno v:
European journal of biochemistry. 267(20)
The prodomains of several cysteine proteases of the papain family have been shown to be potent inhibitors of their parent enzymes. An increased interest in cysteine proteases inhibitors has been generated with potential therapeutic targets such as ca
Autor:
C C, Chan, S, Boyce, C, Brideau, S, Charleson, W, Cromlish, D, Ethier, J, Evans, A W, Ford-Hutchinson, M J, Forrest, J Y, Gauthier, R, Gordon, M, Gresser, J, Guay, S, Kargman, B, Kennedy, Y, Leblanc, S, Leger, J, Mancini, G P, O'Neill, M, Ouellet, D, Patrick, M D, Percival, H, Perrier, P, Prasit, I, Rodger
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 290(2)
The discoveries that cyclooxygenase (COX)-2 is an inducible form of COX involved in inflammation and that COX-1 is the major isoform responsible for the production of prostaglandins (PGs) in the gastrointestinal tract have provided a rationale for th
Publikováno v:
Biochemical and biophysical research communications. 241(1)
Cyclic nucleotide phosphodiesterases (PDE), including PDE4A, contain two consensus sequences (HX3HX24-26E) which have been associated with Zn2+ binding and activation with other proteins. This study shows that Zn2+ activates purified recombinant huma
Autor:
M D Percival, Marc Ouellet
Publikováno v:
The Biochemical journal. 306
Cyclooxygenase (Cox) is a key enzyme in the biosynthesis of prostaglandins and, as such, is the target of non-steroidal anti-inflammatory drugs (NSAIDs). Two isoforms exist, being expressed constitutively (Cox-1), or inducibly in response to inflamma
Autor:
G. P. O’neill, B. P. Kennedy, J. A. Mancini, S. Kargman, M. Ouellet, J. Yergey, J.-P. Falgueyret, W. A. Cromlish, P. Payette, C.-C. Chan, S. A. Culp, C. Vincent, C. Boily, M. Abramovitz, J. F. Evans, A. W. Ford-Hutchinson, P. J. Vickers, M. D. Percival
Publikováno v:
Novel Molecular Approaches to Anti-Inflammatory Therapy ISBN: 9783034872782
The main target of non-steroidal anti-inflammatory drugs (NSAIDs) is prostaglandin G/H synthase (PGHS), also known as cyclooxygenase (COX), which exists as two isoforms. In order to evaluate the contributions of PGHS isoforms to physiological and pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08a561faab377b4e0222a8bf132d0d0b
https://doi.org/10.1007/978-3-0348-7276-8_16
https://doi.org/10.1007/978-3-0348-7276-8_16
Publikováno v:
Biochemistry. 32(37)
Purified human 5-lipoxygenase, a non-heme iron containing enzyme, has been characterized by electron paramagnetic resonance, (EPR), ultraviolet (UV)-visible and fluorescence spectroscopy. As isolated, the enzyme is largely in the ferrous state and sh
Autor:
M D, Percival
Publikováno v:
The Journal of biological chemistry. 266(16)
The iron content of human 5-lipoxygenase has been determined by a colorimetric assay using the chromogenic ligand FerroZine. The highly active enzyme was obtained from a baculovirus expression system and purified using an ATP-agarose chromatography c
Autor:
M D, Percival
Publikováno v:
Proceedings. Symposium on Computer Applications in Medical Care.
The TUMORS Oncology Registry database and functionality has been designed in cooperation with Certified Tumor Registrars and Oncologists, exceeding current American College of Surgeons requirements. The Networked Data Management System provides secur
Publikováno v:
Biochemistry. 29(11)
Phosphoglucomutase is inhibited by a complex formed from alpha-D-glucose 1-phosphate (Glc-1-P) and inorganic vanadate (Vi). Both the inhibition at steady state and the rate of approach to steady state are dependent on the concentrations of both Glc-1