Zobrazeno 1 - 7
of 7
pro vyhledávání: '"M D, Nefedov"'
Autor:
N P, Kuleshov, G D, Cortina-Guerrero, G A, Razinkova, R F, Gar'kavtseva, M D, Nefedov, N Iu, Kuzina, V P, Letiagin
Publikováno v:
Voprosy onkologii. 38(2)
An analysis was carried out of chromosomal site-fragility in patients with primary multiple tumors and familial breast cancer. A possible correlation is discussed between fragile sites, breakpoints in chromosome rearrangements in cancer patients and
Publikováno v:
Voprosy onkologii. 38(11)
A clinico-genealogic investigation was carried out in 216 patients with endometrial cancer. Familial accumulation of endometrial and other cancer incidence was established. The segregation rates appeared to be lower than those expected from simple Me
Publikováno v:
Genetika. 26(12)
Polymorphism of the human c-Ha-ras-1 gene has been analysed in 66 BamHI restricted DNAs from blood of 35 patients with "inherited" breast cancer, 7 fibroadenoma patients, 13 healthy first-degree relatives and 11 unaffected controls. Two "common" and
Publikováno v:
Voprosy onkologii. 36(8)
As a result of clinico-genealogical analysis of data on 691 skin melanoma patients, a classification of skin melanoma was elaborated which reflected the etiologic heterogeneity of the disease. Inheritable and non-inheritable forms of skin melanoma we
Publikováno v:
Sovetskaia meditsina. (9)
Publikováno v:
Genetika. 24(8)
The multifactorial nature of breast cancer was established based on population and family study, the contribution of genetic factors being 52% (premenopausal--62 and postmenopausal--39%). Genetic heterogeneity of different coefficients of inheritance
Publikováno v:
Sovetskaia meditsina. (6)
The authors sum up the results of clinical and genealogic examinations of 2460 patients with most prevalent tumors, i.e. gastric and mammary carcinomas, melanomas. The obtained values of segregation frequencies for these tumors have proved to be lowe