Zobrazeno 1 - 10
of 33
pro vyhledávání: '"M D, Hale"'
Publikováno v:
Age and Ageing. 49:i27-i27
Introduction Self-reported data regarding health conditions are utilised in both clinical practice and research, however, their agreement with general practice records is variable. The extent of this variability is poorly studied among older adults,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5426a42961a88d7e59588336354bca8
https://doi.org/10.1093/ageing/afz192.03
https://doi.org/10.1093/ageing/afz192.03
Publikováno v:
Plant Pathology. 65:334-341
Phytophthora infestans populations can differ in composition as a result of host-specialisation on tomato and potato hosts. In Great Britain many amateur gardeners grow outdoor tomatoes but there is little or no commercial tomato production outdoors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5729a81770371e1a092072c35960d370
https://doi.org/10.1111/ppa.12407
https://doi.org/10.1111/ppa.12407
Autor:
Sergio Sanchez, Lei Zhou, Steven J. Swanson, M. D. Hale, Francesca Civoli, Daniel T. Mytych, Shalini Gupta, Troy E. Barger
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 55:1265-1274
Functional cell-based assays are the preferred method to test for the presence of anti-rHuEPO neutralizing antibodies (NAbs). However, due to the unpredictable nature of test serum matrix effects on cell-based assays, confirmatory assays are essentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98384ed2cf646dbd031e1caa765da5d2
https://doi.org/10.1016/j.jpba.2011.03.029
https://doi.org/10.1016/j.jpba.2011.03.029
Autor:
Adrian Moore, Yongming Gao, Chris Paszty, Fay Vlasseros, Jianhua Gong, Barbara Tipton, Daniel John Lightwood, Alistair James Henry, Jacquelin Jolette, M. D. Hale, Jin Cao, Susan Y. Smith, Michael S. Ominsky, W. Scott Simonet, George Doellgast, David L. Lacey, Jill Cai, Brian Stouch, Rohini Deshpande, Andrew George Popplewell, Lei Zhou, Martyn K. Robinson, Kevin Graham
Publikováno v:
Journal of Bone and Mineral Research. 25:948-959
The development of bone-rebuilding anabolic agents for treating bone-related conditions has been a long-standing goal. Genetic studies in humans and mice have shown that the secreted protein sclerostin is a key negative regulator of bone formation. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dccf634b38a4df943e84067917a54246
https://doi.org/10.1002/jbmr.14
https://doi.org/10.1002/jbmr.14
Autor:
M. D. Hale, Steven J. Kathman
Publikováno v:
Pharmaceutical Statistics. 6:297-306
Development of anti-cancer therapies usually involve small to moderate size studies to provide initial estimates of response rates before initiating larger studies to better quantify response. These early trials often each contain a single tumor type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da5dcee62742c7bde20a7cce7a316a7a
https://doi.org/10.1002/pst.245
https://doi.org/10.1002/pst.245
Autor:
Jean-Paul Squifflet, R. J. Hene, W. Weimar, M T Navarro, J.W. de Fijter, Gert A. Verpooten, M. D. Hale, Andrew J. Nicholls, T. van Gelder, L.B. Hilbrands, Yves Vanrenterghem
Publikováno v:
Transplantation. 68:261-266
Background. Adding a fixed dose of 1 g b.i.d. of mycophenolate mofetil (MMF) to an immunosuppressive regimen consisting of cyclosporine and prednisone results in a 50% reduction in the incidence of acute rejection after kidney transplantation. This s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e428e429469275536648409c6fcd3bea
https://doi.org/10.1097/00007890-199907270-00018
https://doi.org/10.1097/00007890-199907270-00018
Autor:
M. D. Hale, M. P. Denne
Publikováno v:
IAWA Journal. 20:23-36
Cell wall and lumen percentages were determined for vessels, fibres and rays from 10 trees of Nothofagus nervosa (rauli), and analysed in relation to ring number from the pith, ring width, and density. Increase in density across the juvenile wood was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bce86baf51e7265bc27a5b32de938238
https://doi.org/10.1163/22941932-90001544
https://doi.org/10.1163/22941932-90001544
Autor:
Victor W. Armstrong, Philip F. Halloran, Robert B. Ettenger, Paul Keown, Andrew J. Nicholls, David W. Holt, M. D. Hale, Randy Yatscoff, Jane Haley, Leslie M. Shaw, Raman Venkataramanan, Randall E. Morris, Michael Oellerich, Raymond G. Morris
Publikováno v:
Clinical Biochemistry. 31:317-322
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77a49d0f063eaf11cd97176dd66f5e8f
https://doi.org/10.1016/s0009-9120(98)00040-x
https://doi.org/10.1016/s0009-9120(98)00040-x
Publikováno v:
The Journal of Clinical Pharmacology. 36:315-324
A randomized, crossover study of 12 healthy volunteers was conducted with single, 1.5-g doses of mycophenolate mofetil (MMF), a prodrug of mycophenolic acid (MPA), after oral and intravenous administration. During the intravenous infusion, phase syst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::594b69142bfcb9d2ce598849d68b8b21
https://doi.org/10.1002/j.1552-4604.1996.tb04207.x
https://doi.org/10.1002/j.1552-4604.1996.tb04207.x
Publikováno v:
Springer Proceedings in Mathematics & Statistics ISBN: 9781461478454
It is widely accepted that, due to the small size of first-in-human (FIH) trials, safety signals are difficult to detect. The chances of detecting early signals in cardiovascular safety, including heart rate, blood pressure, QT prolongation, etc., ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51dcfe25c8fcbcef7ebed6fc05cd2ad5
https://doi.org/10.1007/978-1-4614-7846-1_23
https://doi.org/10.1007/978-1-4614-7846-1_23
