Zobrazeno 1 - 10
of 14
pro vyhledávání: '"M D, Garrick"'
Publikováno v:
Journal of cellular physiology. 178(3)
Belgrade (b) rats have an autosomal recessive, microcytic, hypochromic anemia. Transferrin (Tf)-dependent iron uptake is defective because of a mutation in DMT1 (Nramp2), blocking endosomal iron efflux. This experiment of nature permits the present s
Publikováno v:
The Journal of biological chemistry. 268(20)
Belgrade rats have an autosomal recessive anemia with hypochromia and microcytosis. Iron uptake into reticulocytes is approximately 20% of normal, but transferrin uptake is unimpaired. We have systematically compared the transferrin cycle in Belgrade
Publikováno v:
Hemoglobin. 11:497-510
Rat hemoglobins are unusually heterogeneous among mammals. This heterogeneity provides multiple opportunities for asynchronies in synthesis and degradation. We have examined rat hemoglobin turnover after an intravenous injection of 2-14C-glycine. Aft
Autor:
M D, Garrick
Publikováno v:
Pediatrics. 83(5 Pt 2)
Autor:
L M, Garrick, L A, Strano-Paul, J E, Hoke, L A, Kirdani-Ryan, R A, Alberico, M M, Everett, R M, Bannerman, M D, Garrick
Publikováno v:
Experimental hematology. 17(5)
Homozygous beta-thalassemic mice show many of the features seen in human beta-thalassemia, such as decreased hemoglobin, hematocrit, and red blood cell count as well as increased reticulocyte count. They also exhibit splenomegaly and a decrease in os
Publikováno v:
Annals of the New York Academy of Sciences. 241
Publikováno v:
The Journal of biological chemistry. 263(7)
We compared the transcription and translation of globin genes in three mouse erythroleukemia cell lines under different conditions in which there is differential expression of beta-major (beta ma) and beta-minor (beta mi). Transcription was measured
Publikováno v:
Preparative biochemistry. 10(5)
Polyacrylamide gel electrophoresis in urea and Triton X-100 of a hemolysate from human fetal red blood cells produces four major protein bands: alpha, beta, and 2 gamma globin chains. We have verified that the latter two are the G gamma and A gamma g
Publikováno v:
Progress in clinical and biological research. 55
Autor:
P P, Dembure, M D, Garrick
Publikováno v:
Blood. 57(6)
Hemoglobin beta-chain synthesis by rabbit erythroid cells was tested for dependence on availability of complementary alpha-chains. Reticulocytes and bone marrow cells were obtained from variant rabbits that have hemoglobin with isoleucine in alpha-ch