Výsledky vyhledávání

Interleukin-7 Reverses Lymphopenia and Improves T-Cell Function in Coronavirus Disease 2019 Patient With Inborn Error of Toll-Like Receptor 3: A Case Report

Autor: M. D. Botney, J. A. Di Paola, R. S. Martin, Isaiah R. Turnbull, M. Morre, N. S. Anand, Richard S. Hotchkiss, Charles C. Caldwell, Monty Mazer, S. Miles, Brooke Sadler, Lyle L. Moldawer, Kenneth E. Remy, James P. Bosanquet, Teresa M. Blood, David A. Striker, A. Hess, Scott C. Brakenridge

Publikováno v: Critical Care Explorations
Critical Care Explorations, Vol 3, Iss 7, p e0500 (2021)

BACKGROUND:. Immunotherapy treatment for coronavirus disease 2019 combined with antiviral therapy and supportive care remains under intense investigation. However, the capacity to distinguish patients who would benefit from immunosuppressive or immun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75ae0a4d6564d0a71bb6317539d56cc2
http://europepmc.org/articles/PMC8322565

Zobrazit plný text záznamu

Effect of Hemorrhage on Medial Collateral Ligament Healing in a Mouse Model

Autor: Rick W. Wright, Manish Parikh, Matthew J. Silva, M D Botney, Tracy Allen, Michael D. Brodt

Publikováno v: The American Journal of Sports Medicine. 31:660-666

BackgroundMedial collateral ligament injuries heal by a scar response.Hypothesisincreased hemorrhage at the site of medial collateral ligament injury improves healing.Study DesignControlled laboratory study.MethodsNinety-six mice were divided into tw

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51bdf450fa6b998d9d9fe7a12b708c94
https://doi.org/10.1177/03635465030310050501

Zobrazit plný text záznamu

Pathologic regression of primary pulmonary hypertension in left native lung following right single-lung transplantation

Autor: Elbert P. Trulock, Nat T. Levy, M. D. Botney, Helen Liapis, Paul R. Eisenberg

Publikováno v: The Journal of Heart and Lung Transplantation. 20:381-384

A 40-year-old female underwent right single-lung transplantation for primary pulmonary hypertension (PPH). The patient survived for 9 years subsequent to the transplant. At autopsy, pathologic examination demonstrated partial resolution of the charac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c188e40f9fadea590ad1e523d07379f
https://doi.org/10.1016/s1053-2498(00)00153-4

Zobrazit plný text záznamu

Criteria for Outpatient Management of Proximal Lower Extremity Deep Venous Thrombosis

Autor: Brian G. Rubin, Robert S. Woodward, Brian F. Gage, M D Botney, Roger D. Yusen, Brennan M. Haraden

Publikováno v: Chest. 115:972-979

Study objectives To develop and to evaluate selection criteria for outpatient management of deep venous thrombosis (DVT). Design We developed outpatient treatment eligibility criteria that incorporated demographic and clinical data. We aimed to exclu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71e881bc6613b55c2f02d52dc0b51272
https://doi.org/10.1378/chest.115.4.972

Zobrazit plný text záznamu

Role of Hemodynamics in Pulmonary Vascular Remodeling

Autor: M D Botney

Publikováno v: American Journal of Respiratory and Critical Care Medicine. 159:361-364

Primary pulmonary hypertension (PPH) is a disease characterized clinically by the progressive increase in pulmonary artery impedance, which ultimately produces right ventricular failure and death. At the time most patients with PPH present to clinica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::730fe625fcdd8d9ca26535fd69aad4d7
https://doi.org/10.1164/ajrccm.159.2.9805075

Zobrazit plný text záznamu

Angiotensin-converting Enzyme Inhibition Delays Pulmonary Vascular Neointimal Formation

Autor: Wei Zhang, M D Botney, Daniel P. Schuster, Matt Bernstein, Kazushige Okada

Publikováno v: American Journal of Respiratory and Critical Care Medicine. 158:939-950

Primary pulmonary hypertension (PPH) is a disease characterized pathologically by pulmonary artery medial hypertrophy, adventitial thickening, and neointimal proliferation. Increasing recognition of the importance of remodeling to the pathogenesis of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d4270f0a12ee855b92998a14a2fa2b9
https://doi.org/10.1164/ajrccm.158.3.9710007

Zobrazit plný text záznamu

Ex vivo liposome-mediated gene transfer to lung isografts

Autor: G. Alexander Patterson, Ronald K. Scheule, Jennifer B. Nietupski, William O. Osburn, Carlos H.R. Boasquevisque, Joel D. Cooper, Matthew Bernstein, Bassem N. Mora, M D Botney

Publikováno v: The Journal of Thoracic and Cardiovascular Surgery. 115:38-44

Objective: Gene therapy is a promising strategy to modify ischemia-reperfusion injury and rejection after transplantation. We evaluated variables that may affect ex vivo gene transfer to rat lung isografts. Methods: Left lungs were harvested and perf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9850bcb08fc43143db039f25e03abe7c
https://doi.org/10.1016/s0022-5223(98)70440-4

Zobrazit plný text záznamu

Liposome-mediated gene transfer to lung isografts

Autor: William O. Osburn, Wei Zhang, Bassem N. Mora, David Peterson, G. Alexander Patterson, Teng C. Lee, Joel D. Cooper, Ronald K. Scheule, Jennifer B. Nietupski, Carlos H.R. Boasquevisque, M D Botney, Matthew Bernstein

Publikováno v: The Journal of Thoracic and Cardiovascular Surgery. 114(5):783-792

Objectives: Our objectives were to determine the feasibility, efficacy, and safety of in vivo and ex vivo liposome-mediated gene transfer to lung isografts. Methods: Fischer rats were divided into three main groups: (1) Nontransplant setting: Liposom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b98249b530a4562eac31ad3d233f1ecb

Zobrazit plný text záznamu

Successful in vivo and ex vivo transfection of pulmonary artery segments in lung isografts

Autor: G. Alexander Patterson, Ronald K. Scheule, Joel D. Cooper, Carlos H.R. Boasquevisque, M D Botney, Motoki Yano

Publikováno v: The Journal of Thoracic and Cardiovascular Surgery. 114:793-802

Objective: Gene transfer to lung grafts may be useful in ameliorating ischemia-reperfusion injury and rejection. Efficient gene transfection to the whole organ may prove problematic. Proximal pulmonary artery endothelial transfection might provide be

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddc73e9c3cc41d9488bfa03d7637a71b
https://doi.org/10.1016/s0022-5223(97)70083-7

Zobrazit plný text záznamu

Inflammatory cell-derived NO modulates cardiac allograft contractile and electrophysiological function

Autor: R. T. Pyo, T. B. Ferguson, T. P. Misko, M D Botney, D. G. Alexander, P. M. Sullivan, N. K. Worrall, W. D. Lazenby

Publikováno v: Scopus-Elsevier

We previously demonstrated that inhibition of inducible nitric oxide (NO) synthase (iNOS) ameliorated acute cardiac allograft rejection. This study used a rat cardiac transplant model to characterize contractile and electrophysiological dysfunction d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69771d307a413978e018a8ed6016c04e
https://doi.org/10.1152/ajpheart.1997.273.1.h28

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání