Zobrazeno 1 - 10
of 1 189
pro vyhledávání: '"M D'Incalci"'
Autor:
Capoluongo ED, B, Pellegrino, Arenare L, Califano D, Scambia G, L, Beltrame, V, Serra, Scaglione GL, Spina A, Cecere SC, De Cecio R, N, Normanno, N, Colombo, Lorusso D, Russo D, Nardelli C, M, D'Incalci, Llop-Guevara A, Pisano C, G, Baldassarre, Mezzanzanica D, Artioli G, Setaro M, Tasca G, C, Roma, Campanini N, Cinieri S, A, Sergi, Musolino A, Perrone F, Chiodini P, S, Marchini, Pignata S
Publikováno v:
Scientia
Molecular testing; Ovarian cancer Proves moleculars; Càncer d'ovaris Pruebas moleculares; Cáncer de ovarios Background The detection of homologous recombination deficiency (HRD) can identify patients who are more responsive to platinum and poly ADP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdf39ab4ed238d4e922aed12d4c930dd
https://hdl.handle.net/11351/8362
https://hdl.handle.net/11351/8362
Autor:
Paolo G. Casali, Roberta Sanfilippo, M. D'Incalci, Maurizio Callari, Marta Barisella, Marina Meroni, Roberta Frapolli, Chiara Fabbroni, Ilaria Craparotta, Nicolò Panini, Laura Mannarino, Sergio Marchini, Sara Ballabio, Ezia Bello
Publikováno v:
Genomics. 113:3439-3448
Myxoid liposarcoma (MLPS) is a rare soft-tissue sarcoma characterised by the expression of FUS-DDIT3 chimera. Trabectedin has shown significant clinical anti-tumour activity against MLPS. To characterise the molecular mechanism of trabectedin sensiti
Autor:
S. Canova, G.L. Ceresoli, F. Grosso, P.A. Zucali, F. Gelsomino, G. Pasello, M. Mencoboni, E. Rulli, F. Galli, I. De Simone, L. Carlucci, A. De Angelis, M. Belletti, M. Bonomi, A. D’Aveni, M. Perrino, F. Bono, D.L. Cortinovis, D. Cortinovis, F. Colonese, M.I. Abbate, L. Sala, E. Sala, M. Perez Gila, F. Pagni, F. Ugo, F. De Vincenzo, A. Santoro, A. Ardizzoni, S. Frega, M. D’Incalci, D. Poli, V. Torri
Background: Malignant pleural mesothelioma (MPM) is a cancer with a high mortality rate and few therapeutic options. After platinum–pemetrexed combination, no further promising drug seems to be effective. Immune checkpoint inhibitors may have some
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bad29d6a2db87ae9ecc56329d3b9dee
https://hdl.handle.net/11577/3464949
https://hdl.handle.net/11577/3464949
Autor:
I. Vergote, A. González-Martín, I. Ray-Coquard, P. Harter, N. Colombo, P. Pujol, D. Lorusso, M.R. Mirza, B. Brasiuniene, R. Madry, J.D. Brenton, M.G.E.M. Ausems, R. Büttner, D. Lambrechts, M. Ausems, J. Brenton, M. Abreu, S. Balboni, S. Banerjee, M. Barberis, M.P. Barretina Ginesta, J.-F. Baurain, M. Bignami, L. Bjorge, P. Blecharz, I. Bruchim, M. Capilna, N. Cerana, A. Cicchetti, D. Collins, N. Concin, M. D’Incalci, B. Davidson, T. de la Motte Rouge, P. De Iaco, F. Demirkiran, H. Denys, T. Doerk, A. Dorum, A. Ferrero, A.P. Fidalgo, M. Genuardi, L. Gladieff, R. Glasspool, C. Grimm, M. Gultekin, E. Hahnen, A. Hasenburg, A. Hegmane, V. Heinzelmann, E. Hogdall, R. Janavicius, S. Jarmalaite, R. Kalachand, R. Kaneva, S. Kilickap, R. Kocian, D. Kolencik, R. Kristeleit, A. Kryzhanivska, A. Leary, B. Lemley, M. Ligtenberg, J.A. López-Guerrero, C.J. Lord, E. Avall-Lundqvist, J. Maenpaa, S. Mahner, F. Marmé, C. Marth, I. McNeish, S. Merkelbach-Bruse, M. Mourits, N. Normanno, A. Oaknin, K. Ojamaa, C. Papdimitriou, F. Penault-Llorca, A.M. Perrone, S. Pignata, E. Pikarsky, E. Rouleau, M. Rubio, A. Sapino, B. Schmalfeldt, J. Sehouli, R. Shapira, K.D. Steffensen, V. Sukhin, J. Syrios, Z. Szallasi, C. Taskiran, M. Terzic, M. Tischkowitz, I. Toth, K. Van de Vijver, M.A. Vardar, B. Wasag, P. Wimberger, E. Witteveen
Publikováno v:
Annals of Oncology, 33, 3, pp. 276-87
Vergote, I, González-Martín, A, Ray-Coquard, I, Harter, P, Colombo, N, Pujol, P, Lorusso, D, Mirza, M R, Brasiuniene, B, Madry, R, Brenton, J D, Ausems, M G E M, Büttner, R, Lambrechts, D, European experts’ consensus group & Dahl Steffensen, K 2022, ' European experts consensus : BRCA/homologous recombination deficiency testing in first-line ovarian cancer ', Annals of Oncology, vol. 33, no. 3, pp. 276-287 . https://doi.org/10.1016/j.annonc.2021.11.013
ANNALS OF ONCOLOGY
Annals of Oncology, 33, 276-87
Vergote, I, González-Martín, A, Ray-Coquard, I, Harter, P, Colombo, N, Pujol, P, Lorusso, D, Mirza, M R, Brasiuniene, B, Madry, R, Brenton, J D, Ausems, M G E M, Büttner, R, Lambrechts, D, European experts’ consensus group & Dahl Steffensen, K 2022, ' European experts consensus : BRCA/homologous recombination deficiency testing in first-line ovarian cancer ', Annals of Oncology, vol. 33, no. 3, pp. 276-287 . https://doi.org/10.1016/j.annonc.2021.11.013
ANNALS OF ONCOLOGY
Annals of Oncology, 33, 276-87
BACKGROUND: Homologous recombination repair (HRR) enables fault-free repair of double-stranded DNA breaks. HRR deficiency is predicted to occur in around half of high-grade serous ovarian carcinomas. Ovarian cancers harbouring HRR deficiency typicall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::048b3ea84583ffb10df0f113446b4777
Autor:
J. Herzog, F. von Klot-Heydenfeldt, S. Jabar, A. Ranft, C. Rossig, U. Dirksen, J. Van den Brande, M. D’Incalci, I. von Luettichau, P. J. Grohar, W. E. Berdel, St. Burdach
Publikováno v:
Sarcoma, Vol 2016 (2016)
Background. Preclinical data indicate that trabectedin followed by irinotecan has strong synergistic effects on Ewing sarcoma. This is presumably due to hypersensitization of the tumor cells to the camptothecin as an effect of trabectedin in addition
Externí odkaz:
https://doaj.org/article/42a82ead95244ea38f1c18b197b6a1fe
Autor:
T Van Gorp, T Mckee, E Yaniz-Galende, E Ioana Braicu, Philip C. Schouten, A Buisson, Y Christinat, Ignace Vergote, S Marchini, C Kramer, P Saintigny, I.L. Ray-Coquard, Eric Hahnen, Lukas C. Heukamp, M D’incalci, E Pujade-Lauraine
Publikováno v:
Ovarian cancer.
Introduction/Background* Recently 3 Phase III first-line studies, PAOLA-1/ENGOT-ov25 (Ray-Coquard et al. NEJM 2019). PRIMA/ENGOT-ov26/GOG-3012 (Gonzales Martin et al. NEJM 2019) and VELIA/GOG-3005 (Coleman et al. NEJM 2019) have demonstrated that the
Autor:
Marina Meroni, Lavinia Morosi, Ilaria Fuso Nerini, Roberta Frapolli, Barbara Blouw, Lucia Minoli, Enrico Davoli, Paolo Ubezio, Luca Porcu, M. D'Incalci, Massimo Zucchetti, Nicolò Panini, Marika Colombo, David W. Kang
Publikováno v:
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-13 (2021)
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-13 (2021)
Background Scarce drug penetration in solid tumours is one of the possible causes of the limited efficacy of chemotherapy and is related to the altered tumour microenvironment. The abnormal tumour extracellular matrix (ECM) together with abnormal blo
Autor:
F. Grosso, L. Mannarino, L. Paracchini, F. Pezzuto, L. Moracci, G.-E. Olteanu, S. Delfanti, M. Callari, S. Penpa, A. Maconi, I. De Simone, C. Bosetti, P. Allavena, S. Marchini, F. Calabrese, M. D'Incalci
Publikováno v:
Journal of Thoracic Oncology. 17:S314
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
E Bignotti, G Benvenuto, L Paracchini, L Zanotti, C Romani, G Tognon, E Calura, D Vicini, M Adorni, MC Paderno, T Bianchi, F Odicino, E Sartori, A Ravaggi, M D'Incalci, S Marchini, P Todeschini, C Romualdi
Publikováno v:
ePoster.
Introduction/Background High-grade serous ovarian carcinoma (HGSOC), the most common and deadly epithelial ovarian cancer histotype is characterized by a heterogeneous genomic landscape. After surgery, all patients are treated with adjuvant platinum