Zobrazeno 1 - 10
of 1 896
pro vyhledávání: '"M D'Amore"'
Publikováno v:
Clinical and Translational Science, Vol 15, Iss 3, Pp 789-798 (2022)
Abstract Bempedoic acid is an ATP citrate lyase inhibitor approved for the treatment of hypercholesterolemia. The objective of this phase I study was to assess the pharmacokinetics (PKs) and safety of bempedoic acid in 24 subjects with normal renal f
Externí odkaz:
https://doaj.org/article/006b738ed5a34d10829d6edcda6839ba
Autor:
P. Pezzella, G. M. Giordano, L. Fazio, L. Giuliani, A. Mucci, P. Bucci, M. Amore, P. Rocca, A. Rossi, A. Perrottelli, E. Caporusso, A. Bertolino, S. Galderisi, M. Maj
Publikováno v:
European Psychiatry, Vol 66, Pp S550-S551 (2023)
Introduction Negative symptoms represent a fundamental aspect of schizophrenia: they have a substantial impact on patients’ real-life functioning and do not respond satisfactorily to currently available treatments. Therefore, a better understanding
Externí odkaz:
https://doaj.org/article/1260dff5b0e64e9da7333dd5f2904192
Autor:
A. Natale, L. Fusar-Poli, S. Sturiale, V. Placenti, M. Marino, A. Amerio, A. Rodolico, C. Concerto, A. Aguglia, A. Petralia, M. S. Signorelli, G. Serafini, M. Amore, E. Aguglia
Publikováno v:
European Psychiatry, Vol 66, Pp S915-S916 (2023)
Introduction People with mental disorders may present impairments in cognitive and metacognitive functions. Self-reflection is the ability to reflect on oneself (specifically on one’s behavior, emotions, and thoughts) and insight is the awareness o
Externí odkaz:
https://doaj.org/article/f8f0225d8474469f857206fb54c04203
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 6, Pp 2487-2496 (2021)
Abstract Bempedoic acid is an inhibitor of adenosine triphosphate–citrate lyase approved for use in adults with hypercholesterolemia. Nonclinical studies assessed binding to the human ether‐a‐go‐go–related gene (hERG) potassium channel in v
Externí odkaz:
https://doaj.org/article/d673bee841e24a1c9ed715ea6899fac6
Autor:
Benny M. Amore, Nikunjkumar Patel, Priya Batheja, Ian E. Templeton, Hannah M. Jones, Michael J. Louie, Maurice G. Emery
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1476 (2023)
The bioequivalence of bempedoic acid oral suspension and commercial immediate release (IR) tablet formulations were assessed using a physiologically based pharmacokinetic (PBPK) model. The mechanistic model, developed from clinical mass balance resul
Externí odkaz:
https://doaj.org/article/f214b47c16e3473abf921b99576bbe8d
Autor:
D. Conti, N. Girone, B. Benatti, O. Gambini, U. Albert, G. Maina, M. Amore, M. Porta, B. Dell’Osso
Publikováno v:
European Psychiatry, Vol 65, Pp S642-S643 (2022)
Introduction Obsessive Compulsive Disorder (OCD) and Tic Disorder (TD) are two highly disabling, comorbid and difficult-to-treat conditions. DSM-5 acknowledged a new “tic-related” specifier for OCD, i.e., Obsessive-Compulsive Tic-related Disorder
Externí odkaz:
https://doaj.org/article/6bd3c238eb1b4f2d81ed7128e0614538
Autor:
A. Natale, L. Fusar-Poli, S. Sturiale, C. Concerto, A. Aguglia, A. Amerio, G. Serafini, M. Amore, E. Aguglia
Publikováno v:
European Psychiatry, Vol 65, Pp S84-S84 (2022)
Introduction Autism spectrum disorder (ASD) is a group of life-long neurodevelopmental conditions characterized by impairments in social communication and by the presence of restricted interests or repetitive behaviors. Several genetic, biological,
Externí odkaz:
https://doaj.org/article/7887877f29fc4dd59933b6e32050d154
Publikováno v:
Atmospheric Chemistry and Physics, Vol 19, Pp 7839-7857 (2019)
This work uses the number concentration-effective diameter phase-space to test cloud sensitivity to variations in the aerosol population characteristics, such as the aerosol size distribution, number concentration and hygroscopicity. It is based on t
Externí odkaz:
https://doaj.org/article/5a29def8702641139c3b2672f134a9a2
Publikováno v:
European Psychiatry, Vol 64, Pp S82-S82 (2021)
Introduction The patterns and clinical correlates related to antidepressant drugs (ADs) prescription for BD remain poorly understood. Objectives This study aimed to compare socio-demographic and clinical features of BD patients treated vs. not trea
Externí odkaz:
https://doaj.org/article/eb9631e1685b49d6aa70023eb55365e9
Publikováno v:
European Psychiatry, Vol 64, Pp S108-S109 (2021)
Introduction Stressful life events (SLE) may influence the illness course and outcome. Objectives The present study aimed to characterize socio-demographic and clinical characteristics of euthymic major depressive disorder (MDD) outpatients with SL
Externí odkaz:
https://doaj.org/article/78901b1691704794919b68667e74d1b1