Zobrazeno 1 - 10
of 53
pro vyhledávání: '"M Cockell"'
Autor:
Susan M. Gasser, Fabien Cubizolles, Fabrizio Martino, Moira M. Cockell, Philip Robinson, Fred van Leeuwen, Stephanie Kueng, Mathias Ziegler, Monika Tsai-Pflugfelder, Daniela Rhodes
Publikováno v:
Molecular Cell. 33:323-334
At yeast telomeres and silent mating-type loci, chromatin assumes a higher-order structure that represses transcription by means of the histone deacetylase Sir2 and structural proteins Sir3 and Sir4. Here, we present a fully reconstituted system to a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::302f32bba06e60a99396e9af38fdcfb6
https://doi.org/10.1016/j.molcel.2009.01.009
https://doi.org/10.1016/j.molcel.2009.01.009
Autor:
Hubert Renauld, Severine Perrod, Moira M. Cockell, Claude C. Bonnard, Susan M. Gasser, Anne-Lyse Ducrest, Thierry Laroche
Publikováno v:
EMBO Journal, Vol. 20, No 1-2 (2001) pp. 197-209
In budding yeast, the silent information regulator Sir2p is a nuclear NAD-dependent deacetylase that is essential for both telomeric and rDNA silencing. All eukaryotic species examined to date have multiple homologues of Sir two (HSTs), which share a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41a611ccf86db2b500f8d4cfa764cd81
https://doi.org/10.1093/emboj/20.1.197
https://doi.org/10.1093/emboj/20.1.197
Autor:
Moira M. Cockell, Susan M. Gasser
Publikováno v:
Current Opinion in Genetics & Development. 9:199-205
Improvements in fluorescence microscopy have allowed us to explore the three-dimensional organization of the nucleus in ways that were impossible ten years ago, revealing subdomains or compartments within the nucleus defined by their enrichments of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ab1ba446a87c13640b9cfec4c4539bd
https://doi.org/10.1016/s0959-437x(99)80030-6
https://doi.org/10.1016/s0959-437x(99)80030-6
Publikováno v:
Cold Spring Harbor Symposia on Quantitative Biology. 63:401-412
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e918cc3ebd798cca5c77991de09e0137
https://doi.org/10.1101/sqb.1998.63.401
https://doi.org/10.1101/sqb.1998.63.401
Autor:
Francesca Palladino, Moira M. Cockell, G Kyrion, C Liu, Susan M. Gasser, Arthur J. Lustig, Thierry Laroche
Publikováno v:
The Journal of Cell Biology
The Silent Information Regulatory proteins, Sir3 and Sir4, and the telomeric repeat-binding protein RAP1 are required for the chromatin-mediated gene repression observed at yeast telomeric regions. All three proteins are localized by immunofluorescen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498bb4308e8435c8282fe89859632c16
https://doi.org/10.1083/jcb.129.4.909
https://doi.org/10.1083/jcb.129.4.909
Publikováno v:
Novartis Foundation Symposium 214-Epigenetics
Europe PubMed Central
Scopus-Elsevier
Europe PubMed Central
Scopus-Elsevier
In budding yeast genes integrated near telomeres succumb to a variegated pattern of gene repression that requires the silent information regulatory proteins Sir2p, Sir3p and Sir4p, which form a nucleosome-binding complex. Immunolocalization shows tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19618182a422866e37a6c3558c0a6410
https://doi.org/10.1002/9780470515501.ch7
https://doi.org/10.1002/9780470515501.ch7
Publikováno v:
Journal of cell science. 117(Pt 19)
We investigated the role of the evolutionarily conserved protein Lis1 in cell division processes of Caenorhabditis elegans embryos. We identified apparent null alleles of lis-1, which result in defects identical to those observed after inactivation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecd4e45f4afdfb5890f1cf5f58387348
https://pubmed.ncbi.nlm.nih.gov/15331665
https://pubmed.ncbi.nlm.nih.gov/15331665
Autor:
Moira M. Cockell, Susan M. Gasser
Publikováno v:
Gene. 279(1)
Silent or heritably repressed genes constitute the major fraction of genetic information in higher eukaryotic cells. Budding yeast has very little consecutively repressed DNA, but what exists has served as a paradigm for the molecular analysis of het
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a725245c0355f9ad62dfba26f2dc795
https://pubmed.ncbi.nlm.nih.gov/11722841
https://pubmed.ncbi.nlm.nih.gov/11722841
Autor:
Monica Gotta, Moira M. Cockell
Publikováno v:
BioEssays : news and reviews in molecular, cellular and developmental biology. 19(5)
Transcription in organisms as diverse as yeast and mammals is subject to chromosomal position effects that result in heritable and variegated patterns of gene expression. Two recent studies have employed a reversible protein-DNA crosslinking method t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba80d013f8d16e0b60caa7b526f28bc1
https://pubmed.ncbi.nlm.nih.gov/9174401
https://pubmed.ncbi.nlm.nih.gov/9174401
We have characterized binding activities in yeast which recognise the T-rich strand of the yeast ARS consensus element and have purified two of these to homogeneity. One (ACBP-60) is detectable in both nuclear and whole cell extracts, while the other
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::434c041917255c7c884d1bc46ea4101e
https://europepmc.org/articles/PMC307742/
https://europepmc.org/articles/PMC307742/