Feasibility of an asthma app to monitor inhaler adherence in primary care: a 4-month prospective multicentre study

Autor: C I Oliveira Jácome, S Rocha, F Cardia, R Lobo, T Ferreira, C Guimarães, A M Cruz, D Morais, R Páscoa, I Vieira, S Silva, C Santos, L Monteiro, R Monteiro, N Rodrigues, M Cepa, M J Faria, A Monteiro Penas, Â Neves, I Rosendo, C Seiça Cardoso, R Oliveira, D Sousa Coelho, J Varanda Marques, B Reis, S Fernandes, P Meireles, F Pimenta, L Salgueiro, M Abreu Aguiar, A R Mourão, A M Pereira, R Almeida, R Amaral, M Alves-Correia, J Correia De Sousa, J Almeida Fonseca

Publikováno v: 01.04 - M-Health/e-health.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9491df9485457e9a3357e78a69a1e10d
https://doi.org/10.1183/13993003.congress-2022.1876

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Structure−Activity Relationships of New A,D-Ring Modified Steroids as Aromatase Inhibitors: Design, Synthesis, and Biological Activity Evaluation

Autor: M. Cepa, Natércia Teixeira, Georgina Correia-da-Silva, Elisiário J. Tavares da Silva, Fernanda M.F. Roleira

Publikováno v: CIÊNCIAVITAE
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Inhibition of aromatase is an efficient approach for the prevention and treatment of breast cancer. New A,D-ring modified steroid analogues of formestane and testolactone were designed and synthesized and their biochemical activity was investigated i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40be3d117bbb527258250d74cb98dd7d
https://doi.org/10.1021/jm050129p

Molecular mechanisms of aromatase inhibition by new A, D-ring modified steroids

Autor: Yanyan Hong, Georgina Correia-da-Silva, Fernanda M.F. Roleira, M. Cepa, Shiuan Chen, Natércia Teixeira, Elisiário J. Tavares da Silva

Publikováno v: Biological chemistry. 389(9)

A recent approach for treatment and prevention of estrogen-dependent breast cancer focuses on the inhibition of aromatase, the enzyme that catalyzes the final step of estrogen biosynthesis. Some synthetic steroids, such as formestane and exemestane,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54d522cacba149aabaae0d4ee0f662e4
https://pubmed.ncbi.nlm.nih.gov/18713005

Synthesis and biochemical studies of 17-substituted androst-3-enes and 3,4-epoxyandrostanes as aromatase inhibitors

Autor: Natércia Teixeira, Fernanda M.F. Roleira, Elisiário J. Tavares da Silva, Georgina Correia-da-Silva, M. Cepa

Publikováno v: Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

A series of 5alpha-androst-3-enes and 3alpha,4alpha-epoxy-5alpha-androstanes were synthesized and tested for their abilities to inhibit aromatase in human placental microsomes. In these series the original C-17 carbonyl group was replaced by hydroxyl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a579289304efcf15ca3c1037fddd7da2