Zobrazeno 1 - 10
of 18
pro vyhledávání: '"M Carmen Lafita-Navarro"'
Autor:
M Carmen Lafita-Navarro, Niranjan Venkateswaran, Jessica A Kilgore, Suman Kanji, Jungsoo Han, Spencer Barnes, Noelle S Williams, Michael Buszczak, Sandeep Burma, Maralice Conacci-Sorrell
Publikováno v:
PLoS Genetics, Vol 16, Iss 11, p e1009117 (2020)
Glioblastoma is the most common and aggressive type of cancer in the brain; its poor prognosis is often marked by reoccurrence due to resistance to the chemotherapeutic agent temozolomide, which is triggered by an increase in the expression of DNA re
Externí odkaz:
https://doaj.org/article/b18a09d25d7e4899a2e3c4dfd0fa497b
Autor:
Niranjan Venkateswaran, Roy Garcia, M. Carmen Lafita-Navarro, Yi-Heng Hao, Lizbeth Perez-Castro, Pedro A. S. Nogueira, Ashley Solmonson, Ilgen Mender, Jessica A. Kilgore, Shun Fang, Isabella N. Brown, Li Li, Emily Parks, Igor Lopes dos Santos, Mahima Bhaskar, Jiwoong Kim, Yuemeng Jia, Andrew Lemoff, Nick V. Grishin, Lisa Kinch, Lin Xu, Noelle S. Williams, Jerry W. Shay, Ralph J. DeBerardinis, Hao Zhu, Maralice Conacci-Sorrell
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Cancer cells exhibit distinct metabolic activities and nutritional dependencies compared to normal cells. Thus, characterization of nutrient demands by individual tumor types may identify specific vulnerabilities that can be manipulated to t
Externí odkaz:
https://doaj.org/article/6ee60b31df8e443cb81fea064aabbe4b
Autor:
M. Carmen Lafita-Navarro, Yi-Heng Hao, Chunhui Jiang, Seoyeon Jang, Tsung-Cheng Chang, Isabella N. Brown, Niranjan Venkateswaran, Elizabeth Maurais, Weronika Stachera, Yanfeng Zhang, Dorothy Mundy, Jungsoo Han, Vanna M. Tran, Marcel Mettlen, Lin Xu, Jeffrey B. Woodruff, Nick V. Grishin, Lisa Kinch, Joshua T. Mendell, Michael Buszczak, Maralice Conacci-Sorrell
Publikováno v:
Cell Reports, Vol 42, Iss 10, Pp 113280- (2023)
Summary: Increased nucleolar size and activity correlate with aberrant ribosome biogenesis and enhanced translation in cancer cells. One of the first and rate-limiting steps in translation is the interaction of the 40S small ribosome subunit with mRN
Externí odkaz:
https://doaj.org/article/c9443ad8099941449a8b52f34efe5875
Autor:
Judit Liaño-Pons, M. Carmen Lafita-Navarro, Lorena García-Gaipo, Carlota Colomer, Javier Rodríguez, Alex von Kriegsheim, Peter J. Hurlin, Fabiana Ourique, M. Dolores Delgado, Anna Bigas, M. Lluis Espinosa, Javier León
Publikováno v:
Oncogenesis, Vol 10, Iss 1, Pp 1-14 (2021)
Abstract MNT, a transcription factor of the MXD family, is an important modulator of the oncoprotein MYC. Both MNT and MYC are basic-helix–loop–helix proteins that heterodimerize with MAX in a mutually exclusive manner, and bind to E-boxes within
Externí odkaz:
https://doaj.org/article/5c3ddc9565e94f44bf82c35b0cab5cde
Autor:
Yi-Heng Hao, M. Carmen Lafita-Navarro, Lauren Zacharias, Nofit Borenstein-Auerbach, Min Kim, Spencer Barnes, Jiwoong Kim, Jerry Shay, Ralph J. DeBerardinis, Maralice Conacci-Sorrell
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-16 (2019)
Abstract Background While regulated WNT activity is required for normal development and stem cell maintenance, mutations that lead to constitutive activation of the WNT pathway cause cellular transformation and drive colorectal cancer. Activation of
Externí odkaz:
https://doaj.org/article/5081501d3fc849a5b04c2db8cc20d343
Autor:
Judit Liaño-Pons, M. Carmen Lafita-Navarro, Lorena García-Gaipo, Carlota Colomer, Javier Rodríguez, Alex von Kriegsheim, Peter J. Hurlin, Fabiana Ourique, M. Dolores Delgado, Anna Bigas, Lluis Espinosa, Javier León
Publikováno v:
Oncogenesis, Vol 10, Iss 8, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/688a64a1b9e5464ebd25656ce977db6e
Publikováno v:
Cells, Vol 11, Iss 574, p 574 (2022)
The nucleolus harbors the machinery necessary to produce new ribosomes which are critical for protein synthesis. Nucleolar size, shape, and density are highly dynamic and can be adjusted to accommodate ribosome biogenesis according to the needs for p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::478e488c8636defd31d0ab52918df44b
https://pubmed.ncbi.nlm.nih.gov/35159381
https://pubmed.ncbi.nlm.nih.gov/35159381
Autor:
Lluis Espinosa, Alex von Kriegsheim, Anna Bigas, Javier Rodriguez, M. Dolores Delgado, Judit Liaño-Pons, Javier León, Peter J. Hurlin, M. Carmen Lafita-Navarro, Lorena García-Gaipo, Carlota Colomer, Fabiana Ourique
Publikováno v:
Oncogenesis
Oncogenesis, Vol 10, Iss 8, Pp 1-1 (2021)
Oncogenesis, Vol 10, Iss 8, Pp 1-1 (2021)
MNT, a transcription factor of the MXD family, is an important modulator of the oncoprotein MYC. Both MNT and MYC are basic-helix-loop-helix proteins that heterodimerize with MAX in a mutually exclusive manner, and bind to E-boxes within regulatory r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cae08ed1e2f5ba9e593ffe3b8611712
http://europepmc.org/articles/PMC8329001
http://europepmc.org/articles/PMC8329001
Autor:
Jonathan Braverman, Min Kim, Thomas Brabletz, Ömer H. Yilmaz, Lizbeth Perez-Castro, Nofit Borenstein-Auerbach, Nicholas P. Lesner, Jessica A. Kilgore, Ralph J. DeBerardinis, Maralice Conacci-Sorrell, Yi Heng Hao, Niranjan Venkateswaran, Prashant Mishra, M. Carmen Lafita-Navarro, Noelle S. Williams, Jerry W. Shay
Publikováno v:
Cell Stress
Tumors display increased uptake and processing of nutrients to fulfill the demands of rapidly proliferating cancer cells. Seminal studies have shown that the proto-oncogene MYC promotes metabolic reprogramming by altering glutamine uptake and metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98805d05a6140e17f32fb7cb4c5b84c4
https://doi.org/10.1101/gad.327056.119
https://doi.org/10.1101/gad.327056.119
Autor:
Javier Rodriguez, Carlota Colomer, Alex von Kriegsheim, Judit Liaño-Pons, Javier León, M. Dolores Delgado, Anna Bigas, Lorena García-Gaipo, M. Lluis Espinosa, Fabiana Ourique, M. Carmen Lafita-Navarro, Peter J. Hurlin
Publikováno v:
Oncogenesis. 2021 Jan 8;10(1):5
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Oncogenesis
Oncogenesis, Vol 10, Iss 1, Pp 1-14 (2021)
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Oncogenesis
Oncogenesis, Vol 10, Iss 1, Pp 1-14 (2021)
© The Author(s) 2021.
MNT, a transcription factor of the MXD family, is an important modulator of the oncoprotein MYC. Both MNT and MYC are basic-helix–loop–helix proteins that heterodimerize with MAX in a mutually exclusive manner, and bin
MNT, a transcription factor of the MXD family, is an important modulator of the oncoprotein MYC. Both MNT and MYC are basic-helix–loop–helix proteins that heterodimerize with MAX in a mutually exclusive manner, and bin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::552320bd41a1754a3391bddf1a16cb92
http://hdl.handle.net/10902/20591
http://hdl.handle.net/10902/20591
