Výsledky vyhledávání - "M Carme Masamunt"

Akademický článek

Macrophage and neutrophil heterogeneity at single-cell spatial resolution in human inflammatory bowel disease

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)

Abstract Ulcerative colitis and Crohn’s disease are chronic inflammatory intestinal diseases with perplexing heterogeneity in disease manifestation and response to treatment. While the molecular basis for this heterogeneity remains uncharacterized,

Externí odkaz: https://doaj.org/article/91914e5f5fdd496f894dce921d226bce

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Akademický článek

Author Correction: Macrophage and neutrophil heterogeneity at single-cell spatial resolution in human inflammatory bowel disease

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)

Externí odkaz: https://doaj.org/article/b3bab41a702941269b02108c15092e84

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Macrophage and neutrophil heterogeneity at single-cell spatial resolution in inflammatory bowel disease

Ulcerative colitis (UC) and Crohn’s disease (CD) are chronic inflammatory intestinal diseases that show a perplexing heterogeneity in manifestations and response to treatment. The molecular basis for this heterogeneity remains uncharacterized. We a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ccd80da16af26ca6d99c6afb1e8d4885
https://doi.org/10.1101/2022.11.28.518139

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Usefulness of Transcriptional Blood Biomarkers as a Non-invasive Surrogate Marker of Mucosal Healing and Endoscopic Response in Ulcerative Colitis

Autor: Anna M. Ramírez, Jordi Guardiola, Núria Planell, Miriam Esteller, Elena Ricart, Sudha Visvanathan, Lorena Rodríguez, Maria de Lourdes Setsuko Ayrizono, Cláudio Saddy Rodrigues Coy, Julián Panés, Azucena Salas, Ingrid Ordás, Ignacio Alfaro, Raquel Franco Leal, Juan José Lozano, M Carme Masamunt

Publikováno v: Journal of Crohn's & Colitis

Background and Aims Ulcerative colitis [UC] is a chronic inflammatory disease of the colon. Colonoscopy remains the gold standard for evaluating disease activity, as clinical symptoms are not sufficiently accurate. The aim of this study is to identif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca9fd93753d498b3e3e7221778950c59
http://europepmc.org/articles/PMC5881703

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Alterations in the epithelial stem cell compartment could contribute to permanent changes in the mucosa of patients with ulcerative colitis

Autor: Raquel Franco Leal, Ingrid Ordás, Eduard Batlle, Javier Martín de Carpi, Rut Mora-Buch, Isabella Dotti, Josep Llach, Núria Planell, Elena Ferrer-Picón, Julián Panés, Azucena Salas, Peter Jung, M Carme Masamunt

Publikováno v: Gut

ObjectiveUC is a chronic inflammatory disease of the colonic mucosa. Growing evidence supports a role for epithelial cell defects in driving pathology. Moreover, long-lasting changes in the epithelial barrier have been reported in quiescent UC. Our a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56b166dd8fe989eac78d2d50e087c67c
https://doi.org/10.1136/gutjnl-2016-312609

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Identification of inflammatory mediators in patients with Crohn's disease unresponsive to anti-TNFα therapy

Autor: Juan José Lozano, Julián Panés, Raquel Franco Leal, Núria Planell, Elena Ricart, Miriam Esteller, Radhika Kajekar, Ingrid Ordás, Azucena Salas, M Carme Masamunt, Isabella Dotti, Harsukh Parmar

Publikováno v: Gut. 64:233-242

Background Anti-tumour necrosis factor α (TNFα) therapy effectively induces and maintains remission in Crohn9s disease (CD). Up to 40% of patients, however, fail to respond to anti-TNFα. Objective To identify the mechanisms underlying the persiste

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81b181e4e596f3bca265da81edd7af5f
https://doi.org/10.1136/gutjnl-2013-306518

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Transcriptional analysis of the intestinal mucosa of patients with ulcerative colitis in remission reveals lasting epithelial cell alterations

Autor: Juan José Lozano, Elena Ricart, Rut Mora-Buch, Azucena Salas, Miriam Esteller, Mireya Jimeno, Núria Planell, Julián Panés, Josep M. Piqué, Ingrid Ordás, M Carme Masamunt

Publikováno v: Gut. 62(7)

Objective Ulcerative colitis (UC) is a chronic condition characterised by the relapsing inflammation despite previous endoscopic and histological healing. Our objective was to identify the molecular signature associated with UC remission. Design We p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::970bbc8a73e16ce55b795b754f2d0db9
https://pubmed.ncbi.nlm.nih.gov/23242120

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Akademický článek

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