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Akademický článek

Eps15R is required for bone morphogenetic protein signalling and differentially compartmentalizes with Smad proteins

Autor: Elizabeth M. Callery, Chong Yon Park, Xin Xu, Haitao Zhu, James C. Smith, Gerald H. Thomsen

Publikováno v: Open Biology, Vol 2, Iss 4 (2012)

Transforming growth factor β superfamily members signal through Smad transcription factors. Bone morphogenetic proteins (BMPs) act via Smads 1, 5 and 8 and TGF-βs signal through Smads 2 and 3. The endocytic adaptor protein Eps15R, or ‘epidermal g

Externí odkaz: https://doaj.org/article/8d205241567b43e38f72bd1c039a9ea4

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Applications of nuclear reprogramming and directed differentiation in vascular regenerative medicine

Autor: Elizabeth M. Callery, Amer A. Rana

Publikováno v: New Biotechnology. 32:191-198

As vertebrates proceed through embryonic development the growing organism cannot survive on diffusion of oxygen and nutrients alone and establishment of vascular system is fundamental for embryonic development to proceed. Dysfunction of the vascular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e13fbfa33542368bbe08d518d68082f
https://doi.org/10.1016/j.nbt.2014.07.005

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BRACHYURY and CDX2 Mediate BMP-Induced Differentiation of Human and Mouse Pluripotent Stem Cells into Embryonic and Extraembryonic Lineages

Autor: Claire E. Senner, Elizabeth M. Callery, Ashley Moffett, James C. Smith, Kathy K. Niakan, Roger A. Pedersen, Matthew Trotter, Myriam Hemberger, Andreia S. Bernardo, Lucy Gardner, Daniel Ortmann, Lee Bardwell, Tiago Faial

Publikováno v: Cell Stem Cell
Cell Stem Cell; Vol 9

SummaryBMP is thought to induce hESC differentiation toward multiple lineages including mesoderm and trophoblast. The BMP-induced trophoblast phenotype is a long-standing paradox in stem cell biology. Here we readdressed BMP function in hESCs and mou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd78c504987bb1e4f12c6fd59957f269

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A divergent Tbx6-related gene and Tbx6 are both required for neural crest and intermediate mesoderm development in Xenopus

Autor: James C. Smith, Elizabeth M. Callery, Gerald H. Thomsen

Publikováno v: Developmental Biology

T-box family transcription factors play many roles in Metazoan development. Here we characterise Tbx6r, a unique Tbx6 paralogue isolated from the amphibian Xenopus. The evolution and developmental integration of this divergent T-box gene within the v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f74e2aea13dcc48713f8b7986ad6785f
https://doi.org/10.1016/j.ydbio.2010.01.013

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There's more than one frog in the pond: A survey of the Amphibia and their contributions to developmental biology

Autor: Elizabeth M. Callery

Publikováno v: Seminars in Cell & Developmental Biology. 17:80-92

The study of developmental biology has benefited greatly from the insights gained using amphibians as experimental models. Although Xenopus is currently the predominant model, much of our embryological knowledge derives from research on other amphibi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::32f15f970fdd501aefe7c4ee491d0d10
https://doi.org/10.1016/j.semcdb.2005.11.001

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Frogs without polliwogs: Evolution of anuran direct development

Autor: Hung Fang, Richard P. Elinson, Elizabeth M. Callery

Publikováno v: BioEssays. 23:233-241

Direct development is the assumption of the adult morphology without progression through an intervening, morphologically distinct, free-living larval phase. We discuss the ecological factors contributing to the evolution of this derived life-history

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7306c1e03ad6ee74327f91b01bf5e7a7
https://doi.org/10.1002/1521-1878(200103)23:3<233::aid-bies1033>3.0.co

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Opercular development and ontogenetic re-organization in a direct-developing frog

Autor: Elizabeth M. Callery, Richard P. Elinson

Publikováno v: Development Genes and Evolution. 210:377-381

The direct-developing frog, Eleutherodactylus coqui, has eliminated the tadpole stage from its ontogeny, and lacks many larval characters. We demonstrate that the dermal folds of E. coqui are homologous with the opercular folds of metamorphosing frog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4e0bb1579f75d9f7adf9755af17c95f
https://doi.org/10.1007/s004270000070

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Thyroid hormone-dependent metamorphosis in a direct developing frog

Autor: Richard P. Elinson, Elizabeth M. Callery

Publikováno v: Proceedings of the National Academy of Sciences. 97:2615-2620

The direct developing anuran, Eleutherodactylus coqui , lacks a tadpole, hatching as a tiny frog. We investigated the role of the metamorphic trigger, thyroid hormone (TH), in this unusual ontogeny. Expression patterns of the thyroid hormone receptor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c79a652dbe7c169e58d57ab41c1cfa4d
https://doi.org/10.1073/pnas.050501097

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