Výsledky vyhledávání - "M C van Eggermond"

Introduction of exogenous class II trans-activator in MHC class II-deficient ABI fibroblasts results in incomplete rescue of MHC class II antigen expression

Autor: A Peijnenburg, S J Gobin, M C van Eggermond, B C Godthelp, N van Graafeiland, P J van den Elsen

Publikováno v: The Journal of Immunology. 159:2720-2727

Previously, we have shown that fibroblasts established from type III bare lymphocyte syndrome patient ABI are characterized by the absence of MHC class II gene expression and a strongly reduced amount of MHC class I transcripts. Complementation analy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7b8de0b8503f89189833836dc1f0d1a5
https://doi.org/10.4049/jimmunol.159.6.2720

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Human T cell repertoire generation in the absence of MHC class II expression results in a circulating CD4+CD8- population with altered physicochemical properties of complementarity-determining region 3

Autor: J Henwood, M C van Eggermond, A H van Boxel-Dezaire, R Schipper, M den Hoedt, A Peijnenburg, O Sanal, F Ersoy, G T Rijkers, B J Zegers, J M Vossen, M J van Tol, P J van den Elsen

Publikováno v: The Journal of Immunology. 156:895-906

In this study, we have investigated the impact of deficient MHC class II expression on the use of TCRBV6 and TCRBJ gene elements, and on the pattern of amino acid incorporation exhibited in the N1-D-N2 segments of the third complementarity-determinin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2293300e5e255c3a3abc185fb83903d4
https://doi.org/10.4049/jimmunol.156.3.895

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Transcriptional control of MHC genes and T cell development in MHC class II deficiency

Autor: B, Godthelp, M C, Van Eggermond, S J, Gobin, P J, Van den Elsen

Publikováno v: Archivum immunologiae et therapiae experimentalis. 47(6)

MHC class II deficiency has proven to be an excellent model to study transcription regulation of MHC genes and T cell development. Cell lines established from MHC class II deficient patients have been of great value for the identification of proteins

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::125fc6c4cbba35218fc5904833efcd67
https://pubmed.ncbi.nlm.nih.gov/10608289

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Incomplete T-cell immune reconstitution in two major histocompatibility complex class II-deficiency/bare lymphocyte syndrome patients after HLA-identical sibling bone marrow transplantation

Autor: B C, Godthelp, M C, van Eggermond, A, Peijnenburg, I, Tezcan, S, van Lierde, M J, van Tol, J M, Vossen, P J, van den Elsen

Publikováno v: Blood. 94(1)

To study the effects of major histocompatibility complex (MHC) class II expression on T-cell development, we have investigated T-cell immune reconstitution in two MHC class II-deficiency patients after allogeneic bone marrow transplantation (allo-BMT

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d7593af636d02ede12d84b57582dcd60
https://pubmed.ncbi.nlm.nih.gov/10381532

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Introduction of exogenous class II trans-activator in MHC class II-deficient ABI fibroblasts results in incomplete rescue of MHC class II antigen expression

Autor: A, Peijnenburg, S J, Gobin, M C, van Eggermond, B C, Godthelp, N, van Graafeiland, P J, van den Elsen

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 159(6)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3d499d78431b5a2b22760a0ae69efc9b
https://pubmed.ncbi.nlm.nih.gov/9300692

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Autor: J, Henwood, M C, van Eggermond, A H, van Boxel-Dezaire, R, Schipper, M, den Hoedt, A, Peijnenburg, O, Sanal, F, Ersoy, G T, Rijkers, B J, Zegers, J M, Vossen, M J, van Tol, P J, van den Elsen

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 156(3)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::90452374717f576b3931fd3e918e822f
https://pubmed.ncbi.nlm.nih.gov/8558015

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A family with an apparent HLA-DR triplet: evidence for exchange of functional HLA-DR beta-genes between different haplotypes

Autor: M G, Tilanus, M C, van Eggermond, H M, Fei, G M, Schreuder, M J, Giphart

Publikováno v: Experimental and clinical immunogenetics. 6(2)

Serological and protein analysis showed that HLA-DR1 and DR2 short (s) segregated together as one haplotype, resulting in a HLA-DR triplet as found in a family study. Both DR1 and DR2 molecules were coordinately expressed and were shown to function a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::300a4cdd4212dc261473e3155a7e2210
https://pubmed.ncbi.nlm.nih.gov/2576521

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