Zobrazeno 1 - 9
of 9
pro vyhledávání: '"M C Wilce"'
Autor:
J L Sexton, M C Wilce, T Colin, G L Wijffels, L Salvatore, S Feil, M W Parker, T W Spithill, C A Morrison
Publikováno v:
The Journal of Immunology. 152:1861-1872
The glutathione S-transferases (FhGST) of the liver fluke Fasciola hepatica have been identified as novel vaccine candidates that protect sheep against a fluke infection. With the use of overlapping peptides covering the predicted amino acid sequence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77f7b2291033b98510b15237795a28b9
https://doi.org/10.4049/jimmunol.152.4.1861
https://doi.org/10.4049/jimmunol.152.4.1861
Publikováno v:
Croatian medical journal. 42(4)
Part of the decipherment of genomic information lies in understanding the structure and function of the protein products of these genes. Protein structure is of further importance because of the molecular basis of many diseases. Structural biology is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f6f4da466a2c84f16385e8420286ea33
https://pubmed.ncbi.nlm.nih.gov/11471188
https://pubmed.ncbi.nlm.nih.gov/11471188
Autor:
J A, Wilce, J P, Vivian, A F, Hastings, G, Otting, R H, Folmer, I G, Duggin, R G, Wake, M C, Wilce
Publikováno v:
Nature structural biology. 8(3)
The coordinated termination of DNA replication is an important step in the life cycle of bacteria with circular chromosomes, but has only been defined at a molecular level in two systems to date. Here we report the structure of an engineered replicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e06deeb46b7a58441f9caae027fc41c7
https://pubmed.ncbi.nlm.nih.gov/11224562
https://pubmed.ncbi.nlm.nih.gov/11224562
Autor:
C S, Bond, R E, Blankenship, H C, Freeman, J M, Guss, M J, Maher, F M, Selvaraj, M C, Wilce, K M, Willingham
Publikováno v:
Journal of molecular biology. 306(1)
Auracyanin B, one of two similar blue copper proteins produced by the thermophilic green non-sulfur photosynthetic bacterium Chloroflexus aurantiacus, crystallizes in space group P6(4)22 (a=b=115.7 A, c=54.6 A). The structure was solved using multipl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d92be03597a13917da3032e7e6739b6
https://pubmed.ncbi.nlm.nih.gov/11178893
https://pubmed.ncbi.nlm.nih.gov/11178893
Autor:
A J, Rodgers, M C, Wilce
Publikováno v:
Nature structural biology. 7(11)
ATP synthases (F(1)F(o)-ATPases) use energy released by the movement of protons down a transmembrane electrochemical gradient to drive the synthesis of ATP, the universal biological energy currency. Proton flow through F(o) drives rotation of a ring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::935d4c9f9fface77be24b28edcbce684
https://pubmed.ncbi.nlm.nih.gov/11062550
https://pubmed.ncbi.nlm.nih.gov/11062550
Autor:
A J, Oakley, M C, Wilce
Publikováno v:
Clinical and experimental pharmacologyphysiology. 27(3)
1. Protein crystallography is an essential tool for the discovery and investigation of pharmacological interactions at the molecular level. It allows investigators to directly visualize the three-dimensional structures of proteins, including enzymes,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::77f93efe103fd44b0fa794ca7aadd45d
https://pubmed.ncbi.nlm.nih.gov/10744339
https://pubmed.ncbi.nlm.nih.gov/10744339
Publikováno v:
Journal of molecular biology. 273(4)
Glutathione S-transferases (GSTs) represent the major class of detoxifying enzymes from parasitic helminths. As a result, they are candidates for chemotherapeutic and vaccine design. Indeed, GSTs from Fasciola hepatica have been found to be effective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b1d0edadb22b51bb3eb9a8c44f3c5b10
https://pubmed.ncbi.nlm.nih.gov/9367777
https://pubmed.ncbi.nlm.nih.gov/9367777
Publikováno v:
Proteins. 27(1)
A tertiary model of the human GSTT2 Theta class glutathione transferase is presented based on the recently solved crystal structure of a related thetalike isoenzyme from Lucilia cuprina. Although the N-terminal domains are quite homologous, the C-ter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f45f6818f5eb1032d9a596d31263c808
https://pubmed.ncbi.nlm.nih.gov/9037717
https://pubmed.ncbi.nlm.nih.gov/9037717
Publikováno v:
Journal of chromatography. 632(1-2)
Amino acid retention coefficients were derived from the experimental retention data of 118 overlapping peptide heptamers related to the primary amino acid sequence of myohemerythrin. Individual retention coefficient values for each amino acid were de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8e0d8ff844574a068a4b4437f0c7c416
https://pubmed.ncbi.nlm.nih.gov/8454713
https://pubmed.ncbi.nlm.nih.gov/8454713