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pro vyhledávání: '"M C Levesque"'
Autor:
M C Levesque, B F Haynes
Publikováno v:
The Journal of Immunology. 159:6184-6194
Ligation of CD44 by hyaluronan (HA) is a key proinflammatory event that regulates lymphocyte and monocyte adhesion and cytokine production. While most immune cells express CD44, few immune cells constitutively bind HA. We have previously shown that m
Autor:
M C Levesque, B F Haynes
Publikováno v:
The Journal of Immunology. 156:1557-1565
CD44 is a cell surface proteoglycan homologous to cartilage link protein that serves as a receptor for hyaluronan (HA). CD44 isoforms include an unspliced 80- to 90-kDa standard form (CD44S) and isoforms derived from alternative splicing of nine CD44
Publikováno v:
The Journal of Immunology. 155:3938-3945
CD44 molecules are cell surface receptors for hyaluronan (HA). To define regions of the extracellular domain of CD44 that are important for HA binding, we have studied the ability of HA-blocking CD44 mAbs to bind to CD44 from a variety of sources. Fi
Autor:
M C Levesque
Publikováno v:
Clinical and experimental immunology. 157(2)
Summary B cell-directed therapies are promising treatments for autoimmune disorders. Besides targeting CD20, newer B cell-directed therapies are in development that target other B cell surface molecules and differentiation factors. An increasing numb
Publikováno v:
The Journal of rheumatology. 27(6)
To determine whether elevated soluble CD44 (sCD44) levels serve as a marker of inflammation and lymphoproliferation in primary Sjögren's syndrome (SS).We measured sCD44 levels by ELISA in serum samples from a cross section of healthy individuals and
Publikováno v:
Arthritis and rheumatism. 42(3)
Human interferon-alpha (IFNalpha) and IFNbeta are administered for treatment of several diseases, including viral infections, malignancies, and multiple sclerosis (MS). IFNalpha therapy has been associated with the production of autoantibodies and th
Publikováno v:
Arthritis and rheumatism. 41(12)
To determine whether monocyte/macrophage expression of the CD6 ligand, activated leukocyte cell adhesion molecule (ALCAM) (CD166), is regulated by cytokines during inflammation in rheumatoid arthritis (RA).We used flow cytometry to test whether cytok
Autor:
M C, Levesque, B F, Haynes
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 159(12)
Ligation of CD44 by hyaluronan (HA) is a key proinflammatory event that regulates lymphocyte and monocyte adhesion and cytokine production. While most immune cells express CD44, few immune cells constitutively bind HA. We have previously shown that m
Autor:
Okouakoua, Frédéric Yannick1,2 (AUTHOR), Kayath, Christian Aimé1,2 (AUTHOR), Mokemiabeka, Saturnin Nicaise1,2 (AUTHOR), Moukala, David Charles Roland1,2 (AUTHOR), Kaya-Ongoto, Moïse Doria1,2 (AUTHOR), Nguimbi, Etienne1,2 (AUTHOR)
Publikováno v:
International Journal of Microbiology. 5/2/2024, Vol. 2024, p1-15. 15p.
Publikováno v:
Investigative ophthalmologyvisual science. 38(10)
CD44 is a major hyaluronic acid receptor that exists as a number of isoforms, generated by alternative splicing of 9 "variant" exons in humans (v2 to v10) and 10 exons in rodents. Little is known about the expression and function of CD44 in human ret