Zobrazeno 1 - 10
of 82
pro vyhledávání: '"M C Carey"'
Publikováno v:
Journal of Lipid Research, Vol 38, Iss 7, Pp 1395-1411 (1997)
Lith genes control susceptibility to cholesterol gallstone formation in inbred strains of mice on a lithogenic diet containing high fat, high cholesterol and 0.5% cholic acid. Our study defines the physical-chemical phenotypes of C57L, AKR, and (C57L
Externí odkaz:
https://doaj.org/article/a8f5173f4bba466a89d3d3c2a58b89a9
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 12, Pp 2539-2549 (1996)
In model biles, five crystallization sequences are present as functions of bile salt/lecithin (egg yolk) ratio and their positions on phase diagrams are influenced by bile salt hydrophobicity, temperature, and total lipid concentration (D. Q-H. Wang
Externí odkaz:
https://doaj.org/article/415bebfc0cee40f9ba19fba0740bc381
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 3, Pp 606-630 (1996)
Using complementary physical-chemical techniques we defined five different crystallization pathways as functions of time (30 days) and increasing lecithin (egg yolk) content in pathophysiologically relevant model biles super-saturated (cholesterol sa
Externí odkaz:
https://doaj.org/article/4965449095e443968f549a926c2d67a1
Autor:
J M Crawford, G M Möckel, A R Crawford, S J Hagen, V C Hatch, S Barnes, J J Godleski, M C Carey
Publikováno v:
Journal of Lipid Research, Vol 36, Iss 10, Pp 2147-2163 (1996)
Physical-chemical and biological studies of hepatic bile suggest that biliary phospholipid molecules are secreted as unilamellar vesicles. Systematic ultrastructural studies of bile canaliculi were undertaken to visualize this event. Liver tissue was
Externí odkaz:
https://doaj.org/article/48d77867170e434abce2dddb4f394a52
Publikováno v:
Journal of Lipid Research, Vol 35, Iss 1, Pp 60-70 (1994)
Despite its importance in cholesterol gallstone formation, crystallization of cholesterol from bile is poorly understood, especially with respect to the influences of other biliary lipids. We reported recently (Konikoff et al. J. Clin. Invest. 1992.
Externí odkaz:
https://doaj.org/article/5cb826726d3140ad8a16eb3e1a452f1b
Publikováno v:
Journal of Lipid Research, Vol 22, Iss 2, Pp 254-270 (1981)
Externí odkaz:
https://doaj.org/article/b447b8063e0249d0969345ec934766bb
Autor:
M J Armstrong, M C Carey
Publikováno v:
Journal of Lipid Research, Vol 23, Iss 1, Pp 70-80 (1982)
To examine quantitatively the hydrophobic-hydrophilic properties of bile salts, we determined the reverse-phase high performance liquid chromatographic (HPLC) mobilities of monomeric bile salt solutions and the equilibrium cholesterol-solubilizing ca
Externí odkaz:
https://doaj.org/article/7f7bd8c2657d475c866a6bc19f12739c
Publikováno v:
Journal of Lipid Research, Vol 21, Iss 1, Pp 72-90 (1980)
We examined by titration the electrochemical properties, apparent pK (pK'a), precipitation pH, and undissociated bile acid solubilities of chenodeoxycholic acid and its 7 beta epimer, ursodeoxycholic acid and their glycine conjugates as functions of
Externí odkaz:
https://doaj.org/article/15590676f47d40a68ad9b180900ad2e4
Autor:
M C Carey
Publikováno v:
Journal of Lipid Research, Vol 19, Iss 8, Pp 945-955 (1978)
A simple method for the rigorous derivation of lithogenic index or percent cholesterol saturation, embodying both relative and total lipid concentrations, is described. We recently demonstrated that under physiological conditions only two key physica
Externí odkaz:
https://doaj.org/article/af37fce72f964547a628460c4b0f4e20
Publikováno v:
Journal of Lipid Research, Vol 26, Iss 4, Pp 428-434 (1985)
Benzo(a)pyrene (BP) was dissolved in dietary fat and fed in a single dose to killifish (Fundulus heteroclitus). Fluorescence microscopic examinations of small intestinal content and frozen sections of whole small intestine revealed that during fat di
Externí odkaz:
https://doaj.org/article/f73fbbbbac154fbdae2c7ea17720024a