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pro vyhledávání: '"M C, van Bruggen"'
Autor:
M C, van Bruggen, J H, Berden
Publikováno v:
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 11(7)
Publikováno v:
Annales de medecine interne. 147(7)
It is generally assumed that anti-dsDNA antibodies play an important role in the pathogenesis of lupus nephritis. This is mainly based on the facts that an increase in anti-dsDNA titer often precedes onset of renal disease, that immune deposits are p
Autor:
M C, van Bruggen, K, Kramers, M N, Hylkema, J, van den Born, M A, Bakker, K J, Assmann, R J, Smeenk, J H, Berden
Publikováno v:
The American journal of pathology. 146(3)
Recently we found in biopsies of human lupus nephritis a nearly complete loss of heparan sulfate (HS) staining in the glomerular basement membrane (GMB). To clarify the relationship between HS staining and albuminuria in lupus nephritis, we studied M
Publikováno v:
The Netherlands journal of medicine. 45(6)
Lupus nephritis is regarded as an immune complex mediated disease. Since anti-DNA antibodies are present in the circulation and in diseased glomeruli of patients with lupus nephritis, these antibodies have been assigned a pivotal role in the initiati