Zobrazeno 1 - 7
of 7
pro vyhledávání: '"M C, Trendle"'
Autor:
Susanna Jacobus, Rafael Fonseca, M. Q. Lacy, P R Greipp, Martin M. Oken, Emily A. Blood, Wee Joo Chng, Gregory J. Ahmann, Syed M. Jalal, Marta Chesi, Morie A. Gertz, P L Bergsagel, Robert A. Kyle, Rafael Santana-Davila, S Van Wier, M. C. Trendle, Kim Henderson, Angela Dispenzieri
Publikováno v:
Leukemia. 20:807-813
Chromosomal hyperdiploidy is the defining genetic signature in 40-50% of myeloma (MM) patients. We characterize hyperdiploid-MM (H-MM) in terms of its clinical and prognostic features in a cohort of 220 H-MM patients entered into clinical trials. Hyp
Autor:
Rafael Santana-Davila, P R Greipp, S Van Wier, Kim Henderson, Martin M. Oken, Marta Chesi, Morie A. Gertz, Robert A. Kyle, Martha Q. Lacy, Rafael Fonseca, Emily A. Blood, P L Bergsagel, A. Hulbert, Wee Joo Chng, Gregory J. Ahmann, Angela Dispenzieri, Syed M. Jalal, Jerry M. Winkler, M. C. Trendle
Publikováno v:
Leukemia Research. 30:266-271
Hyperdiploid and non-hyperdiploid multiple myeloma represents distinct biological entities characterized by different patterns of genetic changes. We sought to determine whether ploidy category (non-hyperdiploid versus hyperdiploid) remains stable ov
Autor:
Robert A. Kyle, Traci Leong, M. C. Trendle, Neil E. Kay, Philip R. Greipp, Martin M. Oken, Jerry A. Katzmann, B Van Ness
Publikováno v:
American Journal of Hematology. 61:232-237
The bone marrow plasma cell labeling index (PCLI) as measured by bromodeoxyuridine uptake is a well-established independent prognostic factor for patients with newly diagnosed multiple myeloma, but the test is not easily done in most laboratories. Th
Autor:
Angela Dispenzieri, Rafael Fonseca, Peter Leif Bergsagel, Marta Chesi, Morie A. Gertz, Syed M. Jalal, Scott Van Wier, Martha Q. Lacy, Rafael Santana-Davila, Robert A. Kyle, Philip R. Greipp, M. C. Trendle, Gregory J. Ahmann, Jerry M. Winkler, Martin M. Oken, Emily A. Blood, Kim Henderson, Wee Joo Chng
Publikováno v:
Blood. 106(6)
Two major genetic categories of multiple myeloma (MM) exist. Hyperdiploid MM (48 to 74 chromosomes, median 53 chromosomes) is associated with trisomies especially of chromosomes 3, 7, 9, 11, 15, and 19, whereas the nonhyperdiploid (< 48 chromosomes o
Publikováno v:
British journal of haematology. 109(1)
Bone involvement is a central feature of multiple myeloma (MM). We investigated whether serum markers of osteoblastic and osteoclastic activity correlate with the presence of bone disease and survival in 313 MM patients enrolled in a phase III trial
Publikováno v:
Cancer. 79(4)
Octreotide, a long-acting somatostatin analogue, has demonstrated clinical utility in patients with carcinoid syndrome and malignant islet cell tumors of the pancreas. Prior studies have reported a greater than expected incidence of cholelithiasis in
Autor:
Wee Joo Chng, Gregory J. Ahmann, Rafael Santana-Davila, Martha Q. Lacy, M. C. Trendle, Peter Leif Bergsagel, Angela Dispenzieri, Martin M. Oken, Scott Van Wier, Emily Blood, Marta Chesi, Morie A. Gertz, Robert A. Kyle, Syed M. Jalal, Kim Henderson, Rafael Fonseca, Philip R. Greipp, Rhett P. Ketterling
Publikováno v:
Blood. 106:1539-1539
H-MM affects about 40–50% of patients, and a similar proportion of MGUS/SMM. The genetic evolution of the disease and the clinical implications of the co-existence of 13q- or t(14q32) are unknown. We conducted a global survey of genetic abnormaliti