Zobrazeno 1 - 4
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pro vyhledávání: '"M C, Skiba"'
Publikováno v:
Journal of Neuroscience Research. 27:472-478
The inherited deficiency of galactosylceramide beta-galactosidase (E.C. 3.2.1.46: galactocerebrosidase) activity results in globoid cell leukodystrophy in humans (Krabbe disease) and in mice (twitcher mutant). To determine whether Krabbe patients' ce
Publikováno v:
Journal of molecular biology. 266(2)
We have analyzed the oligomeric properties of a number of mutant RecA proteins containing single amino acid substitutions within one region of the subunit interface. In contrast to wild-type RecA, which forms a heterogeneous population of different-s
Autor:
M C, Skiba, K L, Knight
Publikováno v:
The Journal of biological chemistry. 269(5)
Assembly of RecA subunits into long, helical oligomers is required for its roles in recombinational DNA repair and homologous genetic recombination. The crystal structure of RecA reveals an extensive network of amino acid residues that lie at the sub
Publikováno v:
American journal of human genetics. 44(2)
Somatic cell hybrids derived from twitcher mouse cells and from control human fibroblasts were selected by two different methods. One method utilized 6-thioguanine-resistant twitcher cells as a parental line and the other used neomycin-resistant cont