Rearrangement in the Hypervariable Region of JC Polyomavirus Genomes Isolated from Patient Samples and Impact on Transcription Factor-Binding Sites and Disease Outcomes

Autor: Michael P. Wilczek, Aiden M. C. Pike, Sophie E. Craig, Melissa S. Maginnis, Benjamin L. King

Publikováno v: International Journal of Molecular Sciences, Vol 23, Iss 10, p 5699 (2022)

JC polyomavirus (JCPyV) is the causative agent of the fatal, incurable, neurological disease, progressive multifocal leukoencephalopathy (PML). The virus is present in most of the adult population as a persistent, asymptotic infection in the kidneys.

Externí odkaz: https://doaj.org/article/9944f63e87b64524ab5725799cc2f1ed

Ovarian cancer risk, ALDH2 polymorphism and alcohol drinking: Asian data from the Ovarian Cancer Association Consortium

Autor: M. C. Pike, Yong-Bing Xiang, Kathryn L. Terry, Georgia Chenevix-Trench, Anna H. Wu, Jennifer A. Doherty, Hui Cai, Marc T. Goodman, Penelope M. Webb, Pamela J. Thompson, Tomotaka Ugai, Linda E. Kelemen, Keitaro Matsuo, David Van Den Berg, Mary Anne Rossing, Yu-Tang Gao, Joellen M. Schildkraut, Andrew Berchuck, Xiao-Ou Shu, Mika Mizuno, Daniel W. Cramer, Celeste Leigh Pearce, Kristine G. Wicklund, Michael E. Carney, Jue-Sheng Ong, Lynne R. Wilkens

Publikováno v: Cancer Science

The aldehyde dehydrogenase 2 (ALDH2) polymorphism rs671 (Glu504Lys) causes ALDH2 inactivation and adverse acetaldehyde exposure among Asians, but little is known of the association between alcohol consumption and rs671 and ovarian cancer (OvCa) in As

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8bdcbacc20f8ccd43e0790b2404441c
http://europepmc.org/articles/PMC5797830

Randomised controlled trial of single BCG, repeated BCG, or combined BCG and killed Mycobacterium leprae vaccine for prevention of leprosy and tuberculosis in Malawi

Autor: N. Maine, R R Jacobson, S. Nyasulu, Fine Pem., Pharoah Pdp., Gruer Pjk., G. K Msiska, S. Kileta, D Ngoma, D S Nyangulu, M Simfukwa, S. M. Oxborrow, D Kawaonja, P.A. Jenkins, M Simwaka, H Tegha, A. Chihana, M. M. Munthali, David Clayton, S Malema, A C McDougall, D Bell, D. K. Warndorff, K Desikan, E Msosa, Janet Darbyshire, Gupte, I Cree, Venance Mwinuka, Richard Peto, J.R. Glynn, J Saul, H Phiri, L. Bliss, M. Kalambo, J. M. Ponnighaus, D. Chavula, P Mkandawire, Sebastian Lucas, B Mwamondwe, M C Pike, Sterne Jac., P Nkhosa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aafbda81703cb5b9c88869d3003e17ad
https://ora.ox.ac.uk/objects/uuid:79dd3ba8-c6d0-493d-92fa-90c295de3b84

Breast cancer and hormone replacement therapy: collaborative reanalysis of data from 51 epidemiological studies of 52,705 women with breast cancer and 108,411 women without breast cancer

Autor: Walter F. Stewart, E. A. Clarke, H. Y. Wei, C. Zhiheng, R. Molina, L. Schuman, Jian-Min Yuan, L. B. Lacaya, Marianne Ewertz, N. Aristizabel, S. Chutivongse, Anthony J. McMichael, De Yun Wang, Carle Paul, C Hermon, Rory Collins, T. Jelihovsky, P. Ontiveros, Baruch Modan, M. Vessey, Jonas Ranstam, Gillian K Reeves, P. C. Nasca, N. Chantarakul, P. Hannaford, B. Javier, Corazon A. Ngelangel, L. M. Kolonel, O. Salas, Giske Ursin, H. P. Lee, T. Yun, Elaine Ron, Clark W. Heath, Marilie D. Gammon, Matti A. Rookus, Timothy J. Key, Leslie Bernstein, R. Shearman, Hoyt G. Wilson, J. Deacon, D. Trichopoulos, Catherine Schairer, T. M.N. Farley, Polly A. Newcomb, A. Morabia, Mimi C. Yu, Mariette Gerber, N. Andrieu, B. Boosiri, P. Jimakorn, Annlia Paganini-Hill, Phyllis A. Wingo, Diana Bull, F. Schofield, A. Bachelot, Martin C. Mahoney, A. M.Y. Nomura, M. C. Leske, R. D. Bulbrook, C. Theetranont, J. Kosmelj, I. S. Fentiman, Nicholas G. Martin, Jack Cuzick, Richard P. Gallagher, J. R. de la Cruz, T. Bishop, Andrew J. Coldman, Ettore Marubini, Suporn Koetsawang, Torgil Möller, Håkan Olsson, W. L. Beeson, T. Rohan, C. Segala, C. Wall, S. Silpisornkosol, J. G. Mati, K. Ebeling, R. Talamini, Lee W. Jones, P. Yang, Robert W. Haile, Anthony B. Miller, B. Crossley, H. Stalsberg, G. Berry, B. Gairard, Hans-Olov Adami, Julian Peto, W. B. Hutchinson, Freda E. Alexander, Howard W. Ory, L. Martinez, M. G. Lê, Robert MacLennan, D. Yeates, R. A. Apelo, M. P. Longnecker, J. Stare, A. Palet, L A Brinton, Monica Ferraroni, Robert Spirtas, Klea Katsouyanni, M. Evstifeeva, Valerie Beral, Chris Bain, A. O. Varma, P. Boyle, O. Meirik, A. L. Weinstein, T. G. Hislop, Dale L. Preston, J. Baens, C. N. Taylor, F Clavel, Kay Cr, Fabio Levi, B. S. Hulka, H. R. Cuevas, N. S. Weiss, Philip A. Band, Sylvia Richardson, Tieng Pardthaisong, R. L. Hanson, Stephen W. Duffy, Mark W. Oberle, Richard Peto, E. Alfandary, Richard Doll, J. L. Hayward, D. Gatei, G. F. S. Spears, Silvia Franceschi, D. Kunde, L. Piana, P. Kenya, Leif Bergkvist, J Cooper Booth, Janet L. Stanford, Kiyohiko Mabuchi, C. E. D. Chilvers, P.A. van den Brandt, Graham A. Colditz, R. Renaud, Robert A. Hiatt, D. Rachawat, C. J. Baines, A. Neil, Victor Siskind, S. R.P. Fine, J. Lansac, S. Holck, F.E. van Leeuwen, M. Primic-Zakelj, J. R. Daling, A. Bràmond, A. Dabancens, Ingemar Persson, E. A. Noonan, Graeme Fraser, C. Wongsrichanalai, Simon Jones, David C. G. Skegg, Pramuan Virutamasen, David B. Thomas, Kathi Malone, A. Cuadros, R. K. Ross, P. Nishan, Robert N. Hoover, Eiliv Lund, B. Ravnihar, Moyses Szklo, Claire E. Lewis, Q. S. Wang, J. A. Schoenberg, C. La Vecchia, R. J. Coates, Emily White, Eugenia E. Calle, Jonathan M. Liff, Antonia Trichopoulou, Gary D. Friedman, Klim McPherson, Luis Rosero-Bixby, M. C. Pike, R.A. Goldbohm, R. Bergkvist, Herbert B. Peterson, S. B. Salazar, A. Kungu, E. Negri

Background. The Collaborative Group on Hormonal Factors in Breast Cancer has brought together and reanalysed about 90% of the worldwide epidemiological evidence on the relation between risk of breast cancer and use of hormone replacement therapy (HRT

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff87d2f66bbbc75c08cac9d650b6820a
https://ora.ox.ac.uk/objects/uuid:1b81f09d-d37a-4646-8acf-b9236a9316a7

Active and passive smoking and the risk of breast cancer in women aged 36-45 years: a population based case-control study in the UK

Autor: Andrew W. Roddam, Julian Peto, M. C. Pike, C Hermon, M. Vessey, C. E. D. Chilvers, Kirstin Pirie, K McPherson, B Crossley, Valerie Beral

Publikováno v: British Journal of Cancer

Active smoking has little or no effect on breast cancer risk but some investigators have suggested that passive smoking and its interaction with active smoking may be associated with an increased risk. In a population based case-control study of brea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5da7f0cd6958507cb1bc9854b71ff01
https://ora.ox.ac.uk/objects/uuid:94a82be7-0990-425e-9ad0-c8a040c5cd15