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of 13
pro vyhledávání: '"M C, Mahony"'
Autor:
M C, Mahony
Publikováno v:
Andrologia. 33(4)
Intracervical insemination continues to be employed for homologous and donor insemination in natural and stimulated cycles. Efficacy studies for potential fertility involve in vivo assessment; however, in vitro testing of particular sperm function(s)
Publikováno v:
Andrologia. 33(4)
The sex of human offspring has been associated with the day in the mother's menstrual cycle on which insemination occurs, with male zygotes being formed earlier in the fertile period than female zygotes. Using an in vitro environment designed to mimi
Publikováno v:
Journal of andrology. 21(4)
For in vitro capacitation to occur in cynomolgus monkey (Macaca fascicularis) spermatozoa, there is an absolute requirement for exogenous stimulation with the sperm activators, caffeine (1 mM) and db-cyclic adenosine monophosphate (dbcAMP) (1 mM), wh
Incidence of aneuploid spermatozoa from subfertile men: selected with motility versus hemizona-bound
Publikováno v:
Human reproduction (Oxford, England). 15(7)
Spermatozoa-zona pellucida binding selects for human spermatozoa with progressive motility, normal morphology and functional competency. We postulated that this gamete interaction would also act to select against spermatozoa with chromosomal numerica
Autor:
M C, Mahony, T, Gwathmey
Publikováno v:
Biology of reproduction. 60(5)
Capacitation and capacitation-related hyperactivated motility do not occur spontaneously in cynomolgus monkey (Macaca fascicularis) spermatozoa; instead, both have an absolute requirement for exogenous stimulation with caffeine and dibutyryl (db)cAMP
Publikováno v:
Journal of andrology. 18(6)
The 5alpha-reduced metabolites of testosterone, including dihydrotestosterone, are considered the primary regulators of epididymal function. Two genes encode two 5alpha-reductase isozymes. We examined 5alpha-reductase type 1 and type 2 mRNA tissue di
Publikováno v:
Molecular reproduction and development. 43(4)
Spermatozoa mature during epididymal transit, acquiring the abilities to swim progressively, fertilize oocytes, and produce viable offspring. In this study, we investigate the capacity of spermatozoa retrieved from the midcorpus and distal cauda regi
Autor:
G. D. Hodgen, Masaki Yamamoto, T. Suzuki, T. Hamashima, T. Kitazaki, Shuzo Sato, F. L. Fort, T. Ando, H. Miyajima, M. C. Mahony
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 26(2)
Lansoprazole is a substituted benzimidazole which inhibits gastric acid secretion by inhibiting the hydrogen-potassium ATPase (proton pump) in the parietal cell. The finding of Leydig cell hyperplasia and Leydig cell tumors in 2-year oral studies in
Publikováno v:
Biology of reproduction. 48(3)
In most species examined to date, spermatozoa mature during transit through the epididymis to become functionally competent to swim progressively, fertilize oocytes, and produce viable offspring. In the studies presented here, the status of spermatoz
Publikováno v:
Journal of andrology. 13(6)
The authors recently reported that fucoidin (a polymer of predominantly L-fucose sulfate) produced a strong, significant, and dose-dependent inhibition of sperm-zona binding under hemizona assay conditions. The current studies were designed to evalua