Zobrazeno 1 - 10
of 17
pro vyhledávání: '"M C, Mahaney"'
Autor:
V. P. Diego, L. Almasy, D. L. Rainwater, M. C. Mahaney, A. G. Comuzzie, S. A. Cole, R. P. Tracy, M. P. Stern, J. W. MacCluer, J. Blangero
Publikováno v:
International Journal of Vascular Medicine, Vol 2010 (2010)
Background. D-dimer is associated with increasing severity of atherosclerosis and with increased risk of a cardiovascular disease (CVD). Methods and Results. To better understand this risk factor, we performed a genome scan on 803 (301 males and 502
Externí odkaz:
https://doaj.org/article/94e690e510c8400a869e310a4e4e5a1f
Publikováno v:
Journal of medical primatology. 32(3)
Although published normative reference standards for hematologic and clinical chemistry measures are available for adult baboons, their applicability to infants has not been addressed. We analyzed these measures in 110 infant baboons (55 females and
Publikováno v:
Genetic epidemiology. 17
Bivariate analyses can improve power to detect linkage. This paper describes one application of a bivariate variance component method for estimating joint likelihoods of a continuous and a discrete trait. This method is applied to the Collaborative S
Autor:
J E, Hixson, L, Almasy, S, Cole, S, Birnbaum, B D, Mitchell, M C, Mahaney, M P, Stern, J W, MacCluer, J, Blangero, A G, Comuzzie
Publikováno v:
The Journal of clinical endocrinology and metabolism. 84(9)
We previously reported that our genome-scanning initiative had detected a highly significant linkage (log odds ratio = 4.95; P = 9 x 10(-7)) between a quantitative trait locus (QTL) on chromosome 2 and leptin levels in Mexican American families. We n
Publikováno v:
Calcified tissue international. 60(3)
Publikováno v:
Laboratory animal science. 47(1)
The gray short-tailed opossum, Monodelphis domestica, is a newly established laboratory animal that is becoming increasingly important to biomedical research. Because little disease information is available for this species, we reviewed records for s
Publikováno v:
Genetic epidemiology. 14(6)
We investigated the utility of two approaches for exploiting pleiotropy to search for genes influencing related traits. To do this we first assessed the genetic correlations among a set of five closely related quantitative traits (Q1, Q2, Q3, Q4, Q5)
Autor:
A G, Comuzzie, J, Blangero, M C, Mahaney, B D, Mitchell, J E, Hixson, P B, Samollow, M P, Stern, J W, MacCluer
Publikováno v:
Genetic epidemiology. 12(5)
Increased adiposity has repeatedly been identified as a major risk factor for a variety of chronic diseases. However, the question still remains whether the amount of adipose tissue itself is genetically mediated. To address this question, a segregat
Publikováno v:
Genetic epidemiology. 12(6)
A quadrivariate quantitative genetic analysis detected significant heritabilities for four simulated quantitative traits (Q1-Q4) with additive genetic pleiotropy between traits Q1, Q2, and Q3. Using univariate segregation analysis, we tentatively det
Publikováno v:
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. 18(6)
A bivariate genetic analysis, utilizing variance decomposition techniques based on maximum likelihood methods, was undertaken to examine the genetic and environmental correlations among eight skinfolds in a large pedigreed sample of Mexican Americans