Zobrazeno 1 - 10
of 26
pro vyhledávání: '"M C, Ganoza"'
Publikováno v:
Nucleic Acids Research
We have previously isolated and described an Escherichia coli ribosome-bound ATPase, RbbA, that is required for protein synthesis in the presence of ATP, GTP and the elongation factors, EF-Tu and EF-G. The gene encoding RbbA, yhih, has been cloned an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e43d0e944dfbf64291f0920b87c33f55
https://doi.org/10.1093/nar/gkj508
https://doi.org/10.1093/nar/gkj508
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 31:215-229
Initiation of translation involves a complex series of reactions that result in the formation of an initiation complex at the proper start site of the mRNA. These reactions, particularly those that involve the binding of the mRNA to the small subunit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76a6c4f2707f8be671f01331f58e4254
https://doi.org/10.1016/s1357-2725(98)00142-3
https://doi.org/10.1016/s1357-2725(98)00142-3
Publikováno v:
Antimicrobial Agents and Chemotherapy. 42:3251-3255
The oxazolidinones represent a new class of antimicrobial agents which are active against multidrug-resistant staphylococci, streptococci, and enterococci. Previous studies have demonstrated that oxazolidinones inhibit bacterial translation in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d54877c4406eea85d4e9a8285f221d8e
https://doi.org/10.1128/aac.42.12.3251
https://doi.org/10.1128/aac.42.12.3251
Publikováno v:
Journal of Biological Chemistry. 270:26377-26381
Reconstitution of protein synthesis from purified translation factors on ribosomes from Escherichia coli has revealed the requirement for a protein, W, that affects chain elongation and is essential to reconstitute the process (Ganoza, M. C., Cunning
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d1d67579b673e7c18c87e999840b366
https://doi.org/10.1074/jbc.270.44.26377
https://doi.org/10.1074/jbc.270.44.26377
Autor:
M C, Kiel, M C, Ganoza
Publikováno v:
European journal of biochemistry. 268(2)
The gene encoding ribosome-bound ATPase (RbbA), which occurs bound to 70S ribosomes and 30S subunits, has been identified. The amino-acid sequence of RbbA reveals the presence of two ATP-binding domains in the N-terminal half of the protein. RbbA har
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::563a13d2913064b880b57caaebc38d84
https://pubmed.ncbi.nlm.nih.gov/11168361
https://pubmed.ncbi.nlm.nih.gov/11168361
Publikováno v:
Molecular biology reports. 15(1)
Initiation factor-free 30S subunits of E. coli ribosomes bind aminoacyl-tRNAs more efficiently than fMet-tRNA inff supMet . Elongator-tRNA binding was unaffected by IF-1 or IF-2 but was inhibited by IF-3. Their combination reduced this binding up to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0da5178287890232b98d3399ef59590d
https://pubmed.ncbi.nlm.nih.gov/1875917
https://pubmed.ncbi.nlm.nih.gov/1875917
Autor:
C. Cunningham, M. C. Ganoza
Publikováno v:
Molecular Biology Reports. 10:115-121
Cupric-ion induced hydrolysis of [35S]Met-tRNA but not of N-formyl-Met-tRNAinffsupMet permitted the specific terminal labelling of initiator tRNA. Initiator tRNA, labeled in this way, was suitable for sequence analysis without the need for further pu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::370a4b2eec3024e340b461f4002c4a31
https://doi.org/10.1007/bf00776984
https://doi.org/10.1007/bf00776984
Publikováno v:
Proceedings of the National Academy of Sciences. 82:1648-1652
To study the mechanism of translation we have attempted to reconstruct the process from purified components. Protein synthesis was programmed by the RNAs of wild-type or amber mutants of bacteriophages f2 or MS2. Translation programmed by MS2 or f2am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc87225e4c67b5407ada4cc0d6bd431d
https://doi.org/10.1073/pnas.82.6.1648
https://doi.org/10.1073/pnas.82.6.1648
Autor:
B. G. Louis, M. C. Ganoza
Publikováno v:
Molecular Biology Reports. 13:103-115
A special methionyl-tRNA (RNAi) is universally required to initiate translation. The conservation of this reactant throughout evolution, as well as its unusual decoding properties, suggested an alternate mechanism for tRNA-mRNA interactions at initia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5ecf4de34460af7815d672ce97f4d66
https://doi.org/10.1007/bf00539058
https://doi.org/10.1007/bf00539058
Autor:
M C Ganoza, T Nakamoto
Publikováno v:
Proceedings of the National Academy of Sciences. 55:162-169
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee97ba8c4a81da52520a141a47b316d6
https://doi.org/10.1073/pnas.55.1.162
https://doi.org/10.1073/pnas.55.1.162