Zobrazeno 1 - 10
of 12
pro vyhledávání: '"M C, Frame"'
Publikováno v:
Cancer research. 61(23)
Although focal adhesion kinase (FAK) is elevated in epithelial cancers, it is not known whether FAK expression influences tumor development in vivo. We found that fak +/- heterozygous mice display reduced 7,12-dimethylbenz[a]anthracene-induced papill
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c3d65455f8f203a238eda56cb9f83451
https://pubmed.ncbi.nlm.nih.gov/11731413
https://pubmed.ncbi.nlm.nih.gov/11731413
Publikováno v:
The Journal of biological chemistry. 276(6)
Integrin-associated focal adhesion complexes provide the main adhesive links between the cellular actin cytoskeleton and the surrounding extracellular matrix. In vitro, cells utilize a complex temporal and spatially regulated mechanism of focal adhes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::589ba2fef0b52802bf3567059e3d666b
https://pubmed.ncbi.nlm.nih.gov/11069922
https://pubmed.ncbi.nlm.nih.gov/11069922
Autor:
O, Loughran, A, Malliri, D, Owens, P H, Gallimore, M A, Stanley, B, Ozanne, M C, Frame, E K, Parkinson
Publikováno v:
Oncogene. 13(3)
We have previously suggested that a gene mapping to chromosome 9p21 could contribute to replicative senescence and suppress cullular immortality in squamous neoplasia. Two candidate genes, the cyclin D1/cyclindependent kinase inhibitors CDKN2A/p16INK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3ce09621187ab1634ac77102bd733470
https://pubmed.ncbi.nlm.nih.gov/8760298
https://pubmed.ncbi.nlm.nih.gov/8760298
Publikováno v:
Oncogene. 12(12)
The product of the c-myc proto-oncogene has a central role in induction of apoptosis, a physiological form of cell death characterised in vitro by morphological rounding, detachment and nuclear disintegration. Induction of apoptosis by serum withdraw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f55aaebc03a1cc270b3cd5d5fba5ea8d
https://pubmed.ncbi.nlm.nih.gov/8700528
https://pubmed.ncbi.nlm.nih.gov/8700528
Publikováno v:
Oncogene. 10(11)
Morphological transformation of cells by the v-Src tyrosine kinase is incompletely understood. However, it is independent of nuclear functions and probably involves phosphorylation of targets associated with the cytoskeleton and focal adhesions, stru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a6506503beca4c08e8fb23e3f71ef8b2
https://pubmed.ncbi.nlm.nih.gov/7784071
https://pubmed.ncbi.nlm.nih.gov/7784071
Publikováno v:
The Journal of biological chemistry. 270(14)
Fibroblasts transformed by the v-Src oncoprotein exhibit elevated activity of the enzyme phosphatidylinositol 3'-kinase (PI 3-kinase), which binds to, and is activated by, a wide range of receptor tyrosine kinases as well as v-Src and transforming po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c12372f27b30a03da64f3ada5ef959d0
https://pubmed.ncbi.nlm.nih.gov/7713890
https://pubmed.ncbi.nlm.nih.gov/7713890
Publikováno v:
Oncogene. 8(7)
Activation of rapidly reversible temperature-sensitive (ts) v-Src in quiescent chicken embryo fibroblasts (CEFs) results in both morphological transformation and exit from G0 to G1, resulting in mitosis. This phenomenon permits examination of cellula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c3bbd1170f7f23afe2617fe7cd4a1eb0
https://pubmed.ncbi.nlm.nih.gov/8510932
https://pubmed.ncbi.nlm.nih.gov/8510932
Publikováno v:
Oncogene. 6(11)
Expression of P0 RNA in some Burkitt lymphoma cell lines varies independently of levels of RNA derived from P1 and P2. These data suggest the possibility that expression of P0 RNA may be capable of independent regulation. In order to investigate this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::261961b50eead387b5834a0e0d8719cd
https://pubmed.ncbi.nlm.nih.gov/1945411
https://pubmed.ncbi.nlm.nih.gov/1945411
Publikováno v:
Journal of Virology. 62:818-825
Hybrid arrest of in vitro translation was used to localize the region of the herpes simplex virus type 1 genome encoding the 65-kilodalton DNA-binding protein (65KDBP) to between genome coordinates 0.592 and 0.649. Knowledge of the DNA sequence of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78d449168c7bb2af151d925d94cd2454
https://doi.org/10.1128/jvi.62.3.818-825.1988
https://doi.org/10.1128/jvi.62.3.818-825.1988