Efficacy and safety of short-course radiotherapy versus total neoadjuvant therapy in older rectal cancer patients: a randomised pragmatic trial (SHAPERS)

Autor: R. Saúde-Conde, T. Vandamme, M. De Backer, P. Martinive, A. Covas, A. Deleporte, A. Dermine, F. Forget, K. Geboes, Q. Gilliaux, Y. Gokburun, E. Gonne, I. Joye, S. Lecomte, G. Liberale, W. Lybaert, L. Moretti, L. Mortier, S. Mupingu Mwanawa, F. Puleo, E.D. Saad, I. Sinapi, L. Annemans, M. Buyse, F. Sclafani

Publikováno v: ESMO Gastrointestinal Oncology, Vol 4, Iss , Pp 100067- (2024)

Although total neoadjuvant therapy (TNT) is a new standard of care for locally advanced rectal cancer (LARC), there are no data to confirm the safety and efficacy of this approach in older patients. SHAPERS is a multicentre, open-label, randomised pr

Externí odkaz: https://doaj.org/article/fba73f9b97c443b8bbc3ea74a8d54b96

Characteristics of pharmacist’s interventions triggered by prescribing errors related to computerised physician order entry in French hospitals: a cross-sectional observational study

Autor: Céline Vermorel, A. Lescoat, Pierrick Bedouch, M.O. Duzanski, L. Bourguignon, N. Thiriat, Bruno Charpiat, Ornella Conort, Jean-Luc Bosson, R. Contreras, S. Roche, A. Fouquet, Manon Videau, S. Abkhtaoui-Couriat, B. Allard-Latour, C. Andrieu, X. Armoiry, E. Armoiry, D. Attivi, L. Audibert, A. Barbet, M. Bascoulergue, C. Basselin, F. Baud, P. Bedouch, M. Belhout, S. Benhaoua, J. Beny, S. Berthet, J. Berthou, D. Bichard, A.C. Blandin, E. Blondel, S. Bonn Loue, A. Bonvin, F. Bouchand, P. Bouniot, M. Bourdelin, C. Bouret, C. Bourne, M. Bouteille, J. Burdin, C. Bureau, M. Burgin, M. Buyse, E. Cabaret, D. Cabelguenne, D. Carli, I. Carpentier, E. Chambrey, S. Chantel, N. Charhon, B. Charpiat, M. Chaumont, K. Civiletti, B. Clerc, M. Cleve, R. Colomb, C. Combe, O. Conort, S. Crepin, M. Creusat-Aube, A. Cuoq, C. Decourcelle, T. Delanoy, C. Derharoutunian, A. Deronze, M. Desseignet, S. Diallo, L. Dietrich, A. Dory, J. Dos-Reis, N. Duarte, L. Escofier, F. Fabre, S. Fare, J. Fillon, A. Fonteneau, A. Gadot, H. Galtier, I. Garreau, C. Gerard, R. Gervais, O. Gloulou, I. GraguebChatti, A. Grass, I. Gremeau, P.Y. Grosse, C. Guenaire, F. Guerin, A. Guillermet, S. Hannou, A. Henry, G. Herbin, N. Herment, A. JanolyDumenil, C. Jarre, L. Jovenaux, M. Juste, A.S. Kaczmarek, W. KiniMatondo, H. Labrosse, C. Laillier, E. Lamarre, J. Lamoureux, M. Laurent, A. Le Bris, M. Le Duff, R. Lecointre, J. Lecompte, M. Lefebvre, A.L. Lepetit, H. Lepont-Gilardi, J.P. Levillain, G. Liguori, C. Lohier, C. Lupo, J. Machon, K. Maes, G. Magerand, K. Mangerel, S. Martelet, D. Matanza, V. Mermet, C. Mouchoux, Y. Nivoix, A. Orly, E. Orng, A. Oufella, I. Paillole, D. Pallot, A. Papon, L. Parnet, M. Paysant, E. Perrier-Cornet, S. Perrin, D. Peynaud, B.N. Pham, D. Piney, A. Pohyer, C. Porot, J. Pouzoulet, L. Poy, E. Prevost, E. Prunier, F. Ranchon, M. Rave, C. Remonnay, M. Remy, M. Rhalimi, C. Rioufol, A. Robelet, F.X. Rose, R. Roubille, A. Sambarino, D. Sankhare, R. Santucci, J. Scholler, R. Selmi, C. Stamm, C. Tanguy, D. Tessier, H. Thery, C. Turci, N. Vantard, N. Vauvarin, D. Viard, C. Vignand, C. Villa, P. Vonna, S. Wacker, N. Wereszczynski, L. Zerhouni

Publikováno v: BMJ Open, Vol 11, Iss 10 (2021)

Objectives Computerised physician order entry (CPOE) systems facilitate the review of medication orders by pharmacists. Reports have emerged that show conception flaws or the misuse of CPOE systems generate prescribing errors. We aimed to characteris

Externí odkaz: https://doaj.org/article/67a8eaf647b34096984ba0488f12634a

Activin A Modulates CRIPTO-1/HNF4α+ Cells to Guide Cardiac Differentiation from Human Embryonic Stem Cells

Autor: Robin Duelen, Guillaume Gilbert, Abdulsamie Patel, Nathalie de Schaetzen, Liesbeth De Waele, Llewelyn Roderick, Karin R. Sipido, Catherine M. Verfaillie, Gunnar M. Buyse, Lieven Thorrez, Maurilio Sampaolesi

Publikováno v: Stem Cells International, Vol 2017 (2017)

The use of human pluripotent stem cells in basic and translational cardiac research requires efficient differentiation protocols towards cardiomyocytes. In vitro differentiation yields heterogeneous populations of ventricular-, atrial-, and nodal-lik

Externí odkaz: https://doaj.org/article/ec180802ac9541a284ff1e0893a521e1

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Human iPSC-Based Model Reveals NOX4 as Therapeutic Target in Duchenne Cardiomyopathy

Autor: L. De Waele, Gunnar M. Buyse, Karin R. Sipido, Nathalie Goemans, Catherine M. Verfaillie, Kaat Desloovere, Guillaume Gilbert, Maurilio Sampaolesi, Domiziana Costamagna, Robin Duelen

Duchenne muscular dystrophy (DMD) is an X-linked progressive muscle disorder, caused by mutations in the Dystrophin gene. Cardiomyopathy is one of the major causes of early death. In this study, we used DMD patient-specific induced pluripotent stem c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::afd0f29c5d13dbbaccbbc615b74b7216
https://doi.org/10.1101/2021.09.13.460090