Zobrazeno 1 - 10
of 161
pro vyhledávání: '"M Brockman"'
Autor:
Kwasi Adu-Berchie, Joshua M. Brockman, Yutong Liu, Tania W. To, David K. Y. Zhang, Alexander J. Najibi, Yoav Binenbaum, Alexander Stafford, Nikolaos Dimitrakakis, Miguel C. Sobral, Maxence O. Dellacherie, David J. Mooney
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Although adoptive T cell therapy provides the T cell pool needed for immediate tumor debulking, the infused T cells generally have a narrow repertoire for antigen recognition and limited ability for long-term protection. Here, we present a h
Externí odkaz:
https://doaj.org/article/c82858dc6c3249e0bed06dcad9fd4919
Autor:
David K. Y. Zhang, Kwasi Adu-Berchie, Siddharth Iyer, Yutong Liu, Nicoletta Cieri, Joshua M. Brockman, Donna Neuberg, Catherine J. Wu, David J. Mooney
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
‘Manufacturing CAR-T cells is a streamlined and highly regulated procedure involving T-cell-expansion and activation on a standardised platform. Here, the authors show that a personalized approach, taking the phenotypic attributes of individual pat
Externí odkaz:
https://doaj.org/article/f7959b99a7e04e99918762da2d538fbb
Autor:
Aaron Blanchard, J. Dale Combs, Joshua M. Brockman, Anna V. Kellner, Roxanne Glazier, Hanquan Su, Rachel L. Bender, Alisina S. Bazrafshan, Wenchun Chen, M. Edward Quach, Renhao Li, Alexa L. Mattheyses, Khalid Salaita
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The authors have recently developed molecular force microscopy (MFM) which uses fluorescence polarisation to measure cell-surface receptor force orientation. Here they show that structured illumination microscopes, which inherently use fluorescence p
Externí odkaz:
https://doaj.org/article/eb25c5882deb4c9a8bdcaa77f44d63b7
Autor:
Roxanne Glazier, Joshua M. Brockman, Emily Bartle, Alexa L. Mattheyses, Olivier Destaing, Khalid Salaita
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Podosomes are protrusive structures that coordinate diverse functions related to cell invasion, migration, bone resorption and immune surveillance. Here the authors integrate DNA nanotechnology with FLIM-FRET to demonstrate that podosomes apply pN in
Externí odkaz:
https://doaj.org/article/4a8b99e9937f47cb9e52b7240832a5e8
Publikováno v:
Medical Education Online, Vol 25, Iss 1 (2020)
Background: Universities are facing increased budget constraints, often resulting in reduced funds to support microbiology laboratories. Online mock laboratory activities are often instituted as a cost-effective alternative to traditional wet labs fo
Externí odkaz:
https://doaj.org/article/74a341dd041447a193fa71cd68100621
Autor:
Aaron Blanchard, J. Dale Combs, Joshua M. Brockman, Anna V. Kellner, Roxanne Glazier, Hanquan Su, Rachel L. Bender, Alisina S. Bazrafshan, Wenchun Chen, M. Edward Quach, Renhao Li, Alexa L. Mattheyses, Khalid Salaita
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/42ad264b3a24425daea024421061ec89
Autor:
C. Schonhofer, K. Andrae-Marobela, J. Yi, A. Cochrane, A. Pagliuzza, B. Abegaz, R. Davis, N. Chomont, Z. Brumme, M. Brockman, I. Tietjen
Publikováno v:
Journal of Virus Eradication, Vol 5, Iss , Pp 15- (2019)
Externí odkaz:
https://doaj.org/article/4e6e37ff7795455d8d1401a4b45573d9
Autor:
Joshua M. Brockman, Khalid Salaita
Publikováno v:
Frontiers in Physics, Vol 7 (2019)
The cells and receptors of the immune system are mechanically active. Single molecule force spectroscopy, traction force microscopy, and molecular tension probe measurements all point to the importance of piconewton (pN) molecular forces in immune fu
Externí odkaz:
https://doaj.org/article/2eb621f1e3c3483e9cb980c52df2383a
Akademický článek
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Autor:
Reizman, Irene M. Brockman, Stenger, Andrew R., Reisch, Chris R., Gupta, Apoorv, Connors, Neal C., Prather, Kristala L.J.
Publikováno v:
In Metabolic Engineering Communications December 2015 2:109-116