Optimal reference genes for RNA tissue analysis in small animal models of hemorrhagic fever viruses

Autor: Katherine A. Davies, Stephen R. Welch, Teresa E. Sorvillo, JoAnn D. Coleman-McCray, María Laura Martin, Julia M. Brignone, Joel M. Montgomery, Christina F. Spiropoulou, Jessica R. Spengler

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)

Abstract Reverse-transcription quantitative polymerase chain reaction assays are frequently used to evaluate gene expression in animal model studies. Data analyses depend on normalization using a suitable reference gene (RG) to minimize effects of va

Externí odkaz: https://doaj.org/article/a5d3c87bfb844e439ea727a71d54082b

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Cost-utility evaluation of vortioxetine in patients with Major Depressive Disorder experiencing inadequate response to alternative antidepressants in the United Kingdom

Autor: L. Evitt, Allan H. Young, M. Brignone, R. Campbell, K. Atsou, Natalya Danchenko, F. Diamand, S. Cure

Publikováno v: Young, A H, Evitt, L, Brignone, M, Diamand, F, Atsou, K, Campbell, R, Cure, S & Danchenko, N 2017, ' Cost-utility evaluation of vortioxetine in patients with Major Depressive Disorder experiencing inadequate response to alternative antidepressants in the United Kingdom ', Journal of Affective Disorders, vol. 218, pp. 291-298 . https://doi.org/10.1016/j.jad.2017.04.019

Background Patients frequently require several lines of therapy for treatment of major depressive episodes. This economic analysis details the management of patients who responded inadequately due to lack of efficacy or intolerability to two previous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::714bb64cd2c1f38cfec3b66b7560fc22
https://doi.org/10.1016/j.jad.2017.04.019

Cost-effectiveness of vortioxetine versus venlafaxine (extended release) in the treatment of major depressive disorder in South Korea

Autor: Dominique Milea, Hong Jin Jeon, Rangrhee Jung, M. Brignone, Sang-Eun Choi, Seong Jin Cho, R. Campbell, Clément François

Publikováno v: Expert Review of Pharmacoeconomics & Outcomes Research. 16:629-638

To assess the cost-effectiveness of vortioxetine versus venlafaxine XR (extended-release) in major depressive disorder (MDD) patients in South Korea.A 1-year cost-effectiveness analysis from a limited societal perspective was performed using a combin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef9424044efb541fc82ee5af28761025
https://doi.org/10.1586/14737167.2016.1128830