Zobrazeno 1 - 10
of 131
pro vyhledávání: '"M Bradley Drummond"'
Autor:
Ruth Tal-Singer PhD, Bruce E Miller PhD, Jean M Rommes PhD, Mark A Luttmann BS, Christophe Demaison PhD, M Bradley Drummond MD, Cara B Pasquale MPH
Publikováno v:
Journal of Patient Experience, Vol 10 (2023)
Patient-centric drug development is crucial to creating treatments that address unmet patient needs but is often ignored. The COPD Foundation's COPD360Net ® includes a multistakeholder approach for operationalizing patient-centric development of tre
Externí odkaz:
https://doaj.org/article/94bac05ec2e941a4bb1026bb469d5d9c
Autor:
Sebastiaan O Verboeket, MD, Anders Boyd, PhD, Ferdinand W Wit, PhD, Eveline Verheij, MD, Maarten F Schim van der Loeff, ProfPhD, Neeltje Kootstra, PhD, Marc van der Valk, PhD, Reindert P van Steenwijk, MD, M Bradley Drummond, MD, Gregory D Kirk, ProfPhD, Peter Reiss, ProfPhD
Publikováno v:
The Lancet. Healthy Longevity, Vol 2, Iss 4, Pp e202-e211 (2021)
Summary: Background: The AGEhIV cohort study is a prospective cohort study evaluating the occurrence of age-related comorbidities in people living with and without HIV. We previously reported a lower forced vital capacity (FVC) in HIV-positive compar
Externí odkaz:
https://doaj.org/article/77ad3f16c05548a086ee81c93c98983f
Autor:
Robert M Burkes, Jacquie Astemborski, Allison A Lambert, Todd T Brown, Robert A Wise, Gregory D Kirk, M Bradley Drummond
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212628 (2019)
IntroductionCathelicidin (also known as LL-37 in humans) is an antimicrobial peptide secreted by epithelial and immune cells and regulated by vitamin D. The immunological roles of cathelicidin make it a putative biomarker to identify individuals at r
Externí odkaz:
https://doaj.org/article/f08947692df24b6889863d9d0292f9ee
Autor:
Nirupama Putcha, Gabriel G Paul, Antoine Azar, Robert A Wise, Wanda K O'Neal, Mark T Dransfield, Prescott G Woodruff, Jeffrey L Curtis, Alejandro P Comellas, M Bradley Drummond, Allison A Lambert, Laura M Paulin, Ashraf Fawzy, Richard E Kanner, Robert Paine, MeiLan K Han, Fernando J Martinez, Russell P Bowler, R Graham Barr, Nadia N Hansel, SPIROMICS investigators
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0194924 (2018)
BACKGROUND:Decreased but measurable serum IgA levels (≤70 mg/dL) have been associated with risk for infections in some populations, but are unstudied in COPD. This study tested the hypothesis that subnormal serum IgA levels would be associated with
Externí odkaz:
https://doaj.org/article/52bc9c5103844d1e9c4b9988c1b87568
Autor:
Wayne H Anderson, Jae Wook Ha, David J Couper, Wanda K O'Neal, R Graham Barr, Eugene R Bleecker, Elizabeth E Carretta, Christopher B Cooper, Claire M Doerschuk, M Bradley Drummond, MeiLan K Han, Nadia N Hansel, Victor Kim, Eric C Kleerup, Fernando J Martinez, Stephen I Rennard, Donald Tashkin, Prescott G Woodruff, Robert Paine, Jeffrey L Curtis, Richard E Kanner, SPIROMICS Research Group
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0184606 (2017)
Understanding the reliability and repeatability of clinical measurements used in the diagnosis, treatment and monitoring of disease progression is of critical importance across all disciplines of clinical practice and in clinical trials to assess the
Externí odkaz:
https://doaj.org/article/68fdfa2ee05a4f66822aae5da11884f2
Autor:
Wei Sun, Katerina Kechris, Sean Jacobson, M Bradley Drummond, Gregory A Hawkins, Jenny Yang, Ting-Huei Chen, Pedro Miguel Quibrera, Wayne Anderson, R Graham Barr, Patricia V Basta, Eugene R Bleecker, Terri Beaty, Richard Casaburi, Peter Castaldi, Michael H Cho, Alejandro Comellas, James D Crapo, Gerard Criner, Dawn Demeo, Stephanie A Christenson, David J Couper, Jeffrey L Curtis, Claire M Doerschuk, Christine M Freeman, Natalia A Gouskova, MeiLan K Han, Nicola A Hanania, Nadia N Hansel, Craig P Hersh, Eric A Hoffman, Robert J Kaner, Richard E Kanner, Eric C Kleerup, Sharon Lutz, Fernando J Martinez, Deborah A Meyers, Stephen P Peters, Elizabeth A Regan, Stephen I Rennard, Mary Beth Scholand, Edwin K Silverman, Prescott G Woodruff, Wanda K O'Neal, Russell P Bowler, SPIROMICS Research Group, COPDGene Investigators
Publikováno v:
PLoS Genetics, Vol 12, Iss 8, p e1006011 (2016)
Implementing precision medicine for complex diseases such as chronic obstructive lung disease (COPD) will require extensive use of biomarkers and an in-depth understanding of how genetic, epigenetic, and environmental variations contribute to phenoty
Externí odkaz:
https://doaj.org/article/917df52f00af40fdb31c85ca727686c7
Autor:
Kieran A Brune, Fernanda Ferreira, Pooja Mandke, Eric Chau, Neil R Aggarwal, Franco R D'Alessio, Allison A Lambert, Gregory Kirk, Joel Blankson, M Bradley Drummond, Athe M Tsibris, Venkataramana K Sidhaye
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0149679 (2016)
Several clinical studies show that individuals with HIV are at an increased risk for worsened lung function and for the development of COPD, although the mechanism underlying this increased susceptibility is poorly understood. The airway epithelium,
Externí odkaz:
https://doaj.org/article/1de8d747f2e949fb8cded452df64150f
Publikováno v:
International Journal of COPD, Vol 2011, Iss default, Pp 89-95 (2011)
M Bradley Drummond1, Gregory D Kirk1,2, Jacquie Astemborski2, Meredith C McCormack1, Mariah M Marshall2, Shruti H Mehta2, Robert A Wise1, Christian A Merlo11Department of Medicine, School of Medicine, 2Department of Epidemiology, Bloomberg School of
Externí odkaz:
https://doaj.org/article/ae59379f957b4757a0a8b2656db520a2
Autor:
Allison A Lambert, Jennifer O Lam, Julie J Paik, Cesar Ugarte-Gil, M Bradley Drummond, Trevor A Crowell
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128004 (2015)
Proton-pump inhibitors (PPIs) are among the most frequently prescribed medications. Community-acquired pneumonia (CAP) is a common cause of morbidity, mortality and healthcare spending. Some studies suggest an increased risk of CAP among PPI users. W
Externí odkaz:
https://doaj.org/article/98b0750e81334789bed0e77b2e384555
Autor:
Allison A Lambert, Gregory D Kirk, Jacquie Astemborski, Enid R Neptune, Shruti H Mehta, Robert A Wise, M Bradley Drummond
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95099 (2014)
BackgroundVitamin D deficiency is associated with reduced lung function. Cathelicidin, an antimicrobial peptide regulated by vitamin D, plays a role within the innate immune system. The association of cathelicidin with lung function decrement and res
Externí odkaz:
https://doaj.org/article/5a90343c7c874585b8c51950618079b0