Zobrazeno 1 - 10 of 26 pro vyhledávání: '"M Bovingdon"'
1
Effect of entacapone, a peripherally acting catechol-O-methyltransferase inhibitor, on the motor response to acute treatment with levodopa in patients with Parkinson's disease
Autor: R Webster, A Gordin, A. J. Lees, M Bovingdon, Marcelo Merello
Publikováno v: Journal of neurology, neurosurgery, and psychiatry. 57(2)
Catechol-O-methyltransferase (COMT) inhibitors may be useful in the treatment of Parkinson's disease by improving the bioavailability of levodopa and by prolonging its effects. Entacapone (OR-611), a novel COMT inhibitor, which does not cross the blo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cab2396e49cfdf8930cc48efdd10c91
https://pubmed.ncbi.nlm.nih.gov/8126502
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2
Hydrogen peroxide and the response of trachea of sensitized guinea-pigs: Opposite effects on contraction and histamine release
Autor: Frederick L. Pearce, B. Y. C. Wan, K. H. Peh, M. Bovingdon, El-Sayed K. Assem
Publikováno v: Inflammation Research. 50:118-119
was seen over the concentration range tested. Frequently, there was an initial “contraction” followed by relaxation to baseline or below. Occasionally, the initial response was a small relaxation. By contrast, H2O2 consistently and dosedependentl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f345a7d958575ef912d18166891ad96
https://doi.org/10.1007/pl00022386
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4
Diurnal differences in response to oral levodopa
Autor: Jp P. Frankel, Z Pirtosek, M Bovingdon, R.A. Webster, A. J. Lees, P A Kempster, G M Stern
Diurnal differences in duration and quality of motor response to levodopa are frequently described by patients. The quality and duration of motor responses were objectively assessed to morning and afternoon oral levodopa doses in five patients with P
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dc6cde26e0c5de46b37e7cd8552e0eb
https://europepmc.org/articles/PMC488274/
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6
The effects of oral protein on the absorption of intraduodenal levodopa and motor performance
Autor: M Bovingdon, Andrew J. Lees, R Webster, J P Frankel, P A Kempster, G M Stern
Publikováno v: Journal of Neurology, Neurosurgery & Psychiatry. 52:1063-1067
Four patients with levodopa induced fluctuations in motor performance were studied during the constant intraduodenal infusion of levodopa. The results confirm that steady plasma levodopa levels with stable motor control can be achieved. However, when
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26644a0db9afa09e8afd8ca87ccc2e2a
https://doi.org/10.1136/jnnp.52.9.1063
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7
Levodopa peripheral pharmacokinetics and duration of motor response in Parkinson's disease
Autor: R Webster, J P Frankel, M Bovingdon, Andrew J. Lees, P A Kempster, G M Stern
Publikováno v: Journal of Neurology, Neurosurgery & Psychiatry. 52:718-723
To assess the relative influence of central pharmacodynamic and peripheral pharmacokinetic factors on the duration of motor response to levodopa, the relationship between motor function and plasma levodopa levels was studied in 31 Parkinsonian patien
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3d3365724d356da132f09a2e01c6536
https://doi.org/10.1136/jnnp.52.6.718
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8
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9
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10
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