Zobrazeno 1 - 10
of 160
pro vyhledávání: '"M Bouwman"'
Autor:
Jinxin Phaedo Chen, Constantin Diekmann, Honggui Wu, Chong Chen, Giulia Della Chiara, Enrico Berrino, Konstantinos L. Georgiadis, Britta A. M. Bouwman, Mohit Virdi, Luuk Harbers, Sara Erika Bellomo, Caterina Marchiò, Magda Bienko, Nicola Crosetto
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Extrachromosomal circular DNAs (eccDNAs) have emerged as important intra-cellular mobile genetic elements that affect gene copy number and exert in trans regulatory roles within the cell nucleus. Here, we describe scCircle-seq, a method for
Externí odkaz:
https://doaj.org/article/6aa437297eed4f71bb53eddd49f2b4bb
Autor:
Frédérique C. M. Bouwman, Bas H. Verhoeven, Willemijn M. Klein, Leo J. Schultze Kool, Ivo de Blaauw
Publikováno v:
Children, Vol 11, Iss 5, p 567 (2024)
Congenital vascular malformations (CVMs) are the result of an aberrant development during embryogenesis. Although these lesions are present at birth, they are not always visible yet. Once symptomatic, patients suffer from pain, bleeding, ulcers, infe
Externí odkaz:
https://doaj.org/article/49368f1e76d842229f270afe8cecccfc
Autor:
Jinxin Phaedo Chen, Constantin Diekmann, Honggui Wu, Chong Chen, Giulia Della Chiara, Enrico Berrino, Konstantinos L. Georgiadis, Britta A. M. Bouwman, Mohit Virdi, Luuk Harbers, Sara Erika Bellomo, Caterina Marchiò, Magda Bienko, Nicola Crosetto
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/5ac93628e7af47f0a456d6850256ac3a
Autor:
Roberto Ballarino, Britta A. M. Bouwman, Federico Agostini, Luuk Harbers, Constantin Diekmann, Erik Wernersson, Magda Bienko, Nicola Crosetto
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-19 (2022)
Measurement(s) DNA Double Strand Break • Transcriptome • Whole Genome Sequencing • Chromosome conformation capture assay • Tumor Suppressor p53-Binding Protein 1 Technology Type(s) sBLISS - Genome-wide detection of DNA double-strand breaks by
Externí odkaz:
https://doaj.org/article/a44d50e03d0b4457bcacd8b05339e16b
Autor:
Veroniek E. M. Harbers, Frédérique C. M. Bouwman, Ingrid M. P. van Rijnsoever, Bas H. Verhoeven, Carine J. M. van der Vleuten, Leo J. Schultze Kool, Peter C. J. de Laat, Chantal M. A. M. van der Horst, Wietske Kievit, D. Maroeska W. M. te Loo
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionVascular malformations are rare congenital anomalies of the vascular system, which can involve the capillaries, veins, arteries, lymphatics, or a combination of vessel types. Patients with vascular malformations experience an impaired hea
Externí odkaz:
https://doaj.org/article/30adb709a8db488493df56d290cc0f8e
Autor:
Nicolas Gaide, Marie-Noëlle Lucas, Mattias Delpont, Guillaume Croville, Kim M. Bouwman, Andreas Papanikolaou, Roosmarijn van der Woude, Iwan A. Gagarinov, Geert-Jan Boons, Robert P. De Vries, Romain Volmer, Angélique Teillaud, Timothée Vergne, Céline Bleuart, Guillaume Le Loc’h, Maxence Delverdier, Jean-Luc Guérin
Publikováno v:
Veterinary Research, Vol 53, Iss 1, Pp 1-15 (2022)
Abstract In late 2015, an epizootic of Highly Pathogenic Avian Influenza (H5Nx) was registered in Southwestern France, including more than 70 outbreaks in commercial poultry flocks. Phylogenetic analyses suggested local emergence of H5 viruses which
Externí odkaz:
https://doaj.org/article/93c73a4567934467a6e2488ea1b21fdd
Autor:
Lin Liu, Pradeep Chopra, Xiuru Li, Kim M. Bouwman, S. Mark Tompkins, Margreet A. Wolfert, Robert P. de Vries, Geert-Jan Boons
Publikováno v:
ACS Central Science, Vol 7, Iss 6, Pp 1009-1018 (2021)
Externí odkaz:
https://doaj.org/article/ef99a56ab01d47058b98ad8209934824
Autor:
Ilhan Tomris, Kim M Bouwman, Youri Adolfs, Danny Noack, Roosmarijn van der Woude, Gius Kerster, Sander Herfst, Rogier W Sanders, Marit J van Gils, Geert-Jan Boons, Bart L Haagmans, R Jeroen Pasterkamp, Barry Rockx, Robert P de Vries
Publikováno v:
PLoS Pathogens, Vol 18, Iss 3, p e1010340 (2022)
SARS-CoV-2 attaches to angiotensin-converting enzyme 2 (ACE2) to gain entry into cells after which the spike protein is cleaved by the transmembrane serine protease 2 (TMPRSS2) to facilitate viral-host membrane fusion. ACE2 and TMPRSS2 expression pro
Externí odkaz:
https://doaj.org/article/dcc13b37132847f5b458e98303166130
Autor:
Tracy J. Ballinger, Britta A. M. Bouwman, Reza Mirzazadeh, Silvano Garnerone, Nicola Crosetto, Colin A. Semple
Publikováno v:
Genome Biology, Vol 20, Iss 1, Pp 1-15 (2019)
Abstract Background Structural variants (SVs) are known to play important roles in a variety of cancers, but their origins and functional consequences are still poorly understood. Many SVs are thought to emerge from errors in the repair processes fol
Externí odkaz:
https://doaj.org/article/0ed9b9678a37451d827a0ab21a8d0656
Autor:
Ilhan Tomris, Luca Unione, Linh Nguyen, Pouya Zaree, Kim M. Bouwman, Lin Liu, Zeshi Li, Jelle A. Fok, María Ríos Carrasco, Roosmarijn van der Woude, Anne L. M. Kimpel, Mirte W. Linthorst, Sinan E. Kilavuzoglu, Enrico C. J. M. Verpalen, Tom G. Caniels, Rogier W. Sanders, Balthasar A. Heesters, Roland J. Pieters, Jesús Jiménez-Barbero, John S. Klassen, Geert-Jan Boons, Robert P. de Vries
Publikováno v:
ACS chemical biology. American Chemical Society
SARS-CoV-2 viruses engage ACE2 as a functional receptor with their spike protein. The S1 domain of the spike protein contains a C-terminal receptor binding domain (RBD) and an N-terminal domain (NTD). The NTD of other coronaviruses includes a glycan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7986185a9b6e04f9b6d48ebf9be5cc9
https://doi.org/10.1021/acschembio.3c00066
https://doi.org/10.1021/acschembio.3c00066