Zobrazeno 1 - 10
of 482
pro vyhledávání: '"M Bossert"'
Autor:
Sarah M. Claypool, David J. Reiner, Sana Behdin, Javier Orihuel, Ashley Batista, Kiera E. Caldwell, Jonathan J. Chow, Jennifer M. Bossert, F. Javier Rubio, Bruce T. Hope, Yavin Shaham
Publikováno v:
The Journal of Neuroscience. 43:2597-2614
We previously demonstrated a role of piriform cortex (Pir) in relapse to fentanyl seeking after food choice-induced voluntary abstinence. Here, we used this model to further study the role of Pir and its afferent projections in fentanyl relapse. We t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::427e41d055dac4bf5f98bbc5ba54c4f2
https://doi.org/10.1523/jneurosci.0034-23.2023
https://doi.org/10.1523/jneurosci.0034-23.2023
Autor:
Jennifer M. Bossert, Carlos A. Mejias-Aponte, Thomas Saunders, Lindsay Altidor, Michael Emery, Ida Fredriksson, Ashley Batista, Sarah M. Claypool, Kiera E. Caldwell, David J. Reiner, Jonathan J. Chow, Matthew Foltz, Vivek Kumar, Audrey Seasholtz, Elizabeth Hughes, Wanda Filipiak, Brandon K. Harvey, Christopher T. Richie, Francois Vautier, Juan L. Gomez, Michael Michaelides, Brigitte L. Kieffer, Stanley J. Watson, Huda Akil, Yavin Shaham
Publikováno v:
The Journal of Neuroscience. 43:1692-1713
The brain µ-opioid receptor (MOR) is critical for the analgesic, rewarding, and addictive effects of opioid drugs. However, in rat models of opioid-related behaviors, the circuit mechanisms of MOR-expressing cells are less known because of a lack of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cfe7ae4967be9d95039228d09b7a62b2
https://doi.org/10.1523/jneurosci.2049-22.2023
https://doi.org/10.1523/jneurosci.2049-22.2023
Autor:
Rajtarun Madangopal, Brendan J Tunstall, Lauren E Komer, Sophia J Weber, Jennifer K Hoots, Veronica A Lennon, Jennifer M Bossert, David H Epstein, Yavin Shaham, Bruce T Hope
Publikováno v:
eLife, Vol 8 (2019)
In abstinent drug addicts, cues formerly associated with drug-taking experiences gain relapse-inducing potency (‘incubate’) over time. Animal models of incubation may help develop treatments to prevent relapse, but these models have ubiquitously
Externí odkaz:
https://doaj.org/article/dd1c5cdadf0c42d6a522a5193016f968
Autor:
Ida Fredriksson, Pei-Jung Tsai, Aniruddha Shekara, Ying Duan, Sarah V. Applebey, Angelica Minier-Toribio, Ashley Batista, Jonathan J. Chow, Lindsay Altidor, Estelle Barbier, Carlo Cifani, Xuan Li, David J. Reiner, F. Javier Rubio, Bruce T. Hope, Yihong Yang, Jennifer M. Bossert, Yavin Shaham
High relapse rate is a key feature of opioid addiction. In humans, abstinence is often voluntary due to negative consequences of opioid seeking. To mimic this human condition, we recently introduced a rat model of incubation of oxycodone craving afte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd72e97aee84d70276cd8053e48c863
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-191360
http://urn.kb.se/resolve?urn=urn:nbn:se:liu:diva-191360
Autor:
Jennifer M. Bossert, Carlos A. Mejias-Aponte, Thomas Saunders, Lindsay Altidor, Michael Emery, Ida Fredriksson, Ashley Batista, Sarah M. Claypool, Kiera E. Caldwell, David J. Reiner, Jonathan J. Chow, Matthew Foltz, Vivek Kumar, Audrey Seasholtz, Elizabeth Hughes, Wanda Filipiak, Brandon K. Harvey, Christopher T. Richie, Francois Vautier, Juan L. Gomez, Michael Michaelides, Brigitte L. Kieffer, Stanley J. Watson, Huda Akil, Yavin Shaham
The brain µ-opioid receptor (MOR) is critical for the analgesic, rewarding, and addictive effects of opioid drugs. However, in rat models of opioid-related behaviors, the circuit mechanisms of MOR-expressing cells are less known because of a lack of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef2d43e95e8230d1fbe7e3799e7f89ec
https://doi.org/10.1101/2022.11.02.514895
https://doi.org/10.1101/2022.11.02.514895
Autor:
Jennifer M. Bossert, Yavin Shaham, Marco Venniro, Ida Fredriksson, Jonathan J Chow, David J. Reiner
Publikováno v:
Pharmacological Reviews. 73:1050-1083
Relapse to drug use during abstinence is a defining feature of addiction. During the last several decades, this clinical scenario has been studied at the preclinical level using classic relapse/reinstatement models in which drug seeking is assessed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b40d4f5b4a3a4e09df674fd36a51a7c1
https://doi.org/10.1124/pharmrev.120.000191
https://doi.org/10.1124/pharmrev.120.000191
Autor:
Olivia R Drake, Bruce T. Hope, Jennifer M. Bossert, Leslie A. Ramsey, Veronica A Lennon, Brendan J. Tunstall, Rajtarun Madangopal, Megan B Brenner, Lauren E Komer, Sophia J Weber, Yavin Shaham
Publikováno v:
Neuropsychopharmacology
Persistent susceptibility to cue-induced relapse is a cardinal feature of addiction. Discriminative stimuli (DSs) are one type of drug-associated cue that signal drug availability (DS+) or unavailability (DS−) and control drug seeking prior to rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::553271639e902469e3ee01f897f3b41e
https://doi.org/10.1038/s41386-021-01067-6
https://doi.org/10.1038/s41386-021-01067-6
Autor:
Shruthi A. Thomas, Bruce E. Blough, David Perekopskiy, David H. Epstein, Eugene A. Kiyatkin, Jennifer K. Hoots, Ida Fredriksson, Anum Afzal, Yavin Shaham, Hannah Korah, S. Stevens Negus, Jennifer M. Bossert
Publikováno v:
Biological Psychiatry. 88:935-944
Background Maintenance treatment with opioid agonists (buprenorphine, methadone) is effective for opioid addiction but does not eliminate opioid use in all patients. We modeled maintenance treatment in rats that self-administered the prescription opi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebf321f88f871cc0e5973237a7ed6e7a
https://doi.org/10.1016/j.biopsych.2020.02.014
https://doi.org/10.1016/j.biopsych.2020.02.014
Autor:
Yavin Shaham, Angelica Minier-Toribio, Sarah V. Applebey, Aniruddha Shekara, Ida Fredriksson, Jennifer M. Bossert
Publikováno v:
Neuropsychopharmacology
In the classical incubation of drug craving rat model, drug seeking is assessed after homecage forced abstinence. However, human abstinence is often voluntary because negative consequences of drug seeking outweigh the desire for the drug. Here, we de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec1cc1cdfb5de8f6a633a6066200c00c
https://doi.org/10.1038/s41386-020-0602-6
https://doi.org/10.1038/s41386-020-0602-6
Autor:
Aniruddha Shekara, Ying Duan, Ida Fredriksson, Pei Jung Tsai, Yihong Yang, Sarah V. Applebey, Jennifer M. Bossert, Hanbing Lu, Yavin Shaham
Publikováno v:
Proc Natl Acad Sci U S A
We recently introduced a rat model of incubation of opioid craving after voluntary abstinence induced by negative consequences of drug seeking. Here, we used resting-state functional MRI to determine whether longitudinal functional connectivity chang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7814f1df9f27e4716dbd345317d4402
https://doi.org/10.1073/pnas.2106624118
https://doi.org/10.1073/pnas.2106624118