Zobrazeno 1 - 10
of 372
pro vyhledávání: '"M Blanton"'
Autor:
Brianna F. Moon, Iris Y. Zhou, Yingying Ning, Yin‐Ching I. Chen, Mariane Le Fur, Sergey Shuvaev, Eman A. Akam, Hua Ma, Cesar Molinos Solsona, Jonah Weigand‐Whittier, Nicholas Rotile, Lida P. Hariri, Matthew Drummond, Avery T. Boice, Samantha E. Zygmont, Yamini Sharma, Rod R. Warburton, Gregory L. Martin, Robert M. Blanton, Barry L. Fanburg, Nicholas S. Hill, Peter Caravan, Krishna C. Penumatsa
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 14 (2024)
Background Aging‐associated left ventricular dysfunction promotes cardiopulmonary fibrogenic remodeling, Group 2 pulmonary hypertension (PH), and right ventricular failure. At the time of diagnosis, cardiac function has declined, and cardiopulmonar
Externí odkaz:
https://doaj.org/article/fa3b4d084c534778b2beccd7d0657d41
Autor:
Furkan Bestepe, Colette Fritsche, Kartik Lakhotiya, Carolyn E. Niosi, George F. Ghanem, Gregory L. Martin, Ruma Pal-Ghosh, Dakota Becker-Greene, James Weston, Ivana Hollan, Ivar Risnes, Stein Erik Rynning, Liv Heidi Solheim, Mark W. Feinberg, Robert M. Blanton, Basak Icli
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 995-1009 (2023)
Angiogenesis is critical for tissue repair following myocardial infarction (MI), which is exacerbated under insulin resistance or diabetes. MicroRNAs are regulators of angiogenesis. We examined the metabolic regulation of miR-409-3p in post-infarct a
Externí odkaz:
https://doaj.org/article/900c2a0bbc3d4984a95a1425cd183424
Autor:
Jessica M. Blanton, Logan M. Peoples, Mackenzie E. Gerringer, Caroline M. Iacuaniello, Natalya D. Gallo, Thomas D. Linley, Alan J. Jamieson, Jeffrey C. Drazen, Douglas H. Bartlett, Eric E. Allen
Publikováno v:
mSphere, Vol 7, Iss 2 (2022)
ABSTRACT Hadal snailfishes are the deepest-living fishes in the ocean, inhabiting trenches from depths of ∼6,000 to 8,000 m. While the microbial communities in trench environments have begun to be characterized, the microbes associated with hadal m
Externí odkaz:
https://doaj.org/article/954801faa63d4ebcad6f59e89658491f
Autor:
Sheila Podell, Jessica M. Blanton, Aaron Oliver, Michelle A. Schorn, Vinayak Agarwal, Jason S. Biggs, Bradley S. Moore, Eric E. Allen
Publikováno v:
Microbiome, Vol 8, Iss 1, Pp 1-17 (2020)
Abstract Background Marine sponges and their microbiomes contribute significantly to carbon and nutrient cycling in global reefs, processing and remineralizing dissolved and particulate organic matter. Lamellodysidea herbacea sponges obtain additiona
Externí odkaz:
https://doaj.org/article/c5ad25798c8e457b9bd9e5d56ef02c86
Autor:
Timothy D. Calamaras, Suchita Pande, Robert A.U. Baumgartner, Seung Kyum Kim, Joseph C. McCarthy, Gregory L. Martin, Kelly Tam, Angela L. McLaughlin, Guang-rong Wang, Mark J. Aronovitz, Weiyu Lin, Jonathan I. Aguirre, Paulina Baca, Peiwen Liu, Daniel A. Richards, Roger J. Davis, Richard H. Karas, Iris Z. Jaffe, Robert M. Blanton
Publikováno v:
JCI Insight, Vol 6, Iss 18 (2021)
cGMP-dependent protein kinase 1α (PKG1α) promotes left ventricle (LV) compensation after pressure overload. PKG1-activating drugs improve heart failure (HF) outcomes but are limited by vasodilation-induced hypotension. Signaling molecules that medi
Externí odkaz:
https://doaj.org/article/5cb3bfd35e8f4781898dd9135f28a00f
Autor:
Se Jin Song, Jon G. Sanders, Frédéric Delsuc, Jessica Metcalf, Katherine Amato, Michael W. Taylor, Florent Mazel, Holly L. Lutz, Kevin Winker, Gary R. Graves, Gregory Humphrey, Jack A. Gilbert, Shannon J. Hackett, Kevin P. White, Heather R. Skeen, Sarah M. Kurtis, Jack Withrow, Thomas Braile, Matthew Miller, Kevin G. McCracken, James M. Maley, Vanessa O. Ezenwa, Allison Williams, Jessica M. Blanton, Valerie J. McKenzie, Rob Knight
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
ABSTRACT Diet and host phylogeny drive the taxonomic and functional contents of the gut microbiome in mammals, yet it is unknown whether these patterns hold across all vertebrate lineages. Here, we assessed gut microbiomes from ∼900 vertebrate spec
Externí odkaz:
https://doaj.org/article/4c88416112104851bafba75448d168c3
Autor:
Joseph C. McCarthy, MS, Mark Aronovitz, MS, Jennifer J. DuPont, PhD, Timothy D. Calamaras, PhD, Iris Z. Jaffe, MD, PhD, Robert M. Blanton, MD
Publikováno v:
JACC: Basic to Translational Science, Vol 2, Iss 3, Pp 285-296 (2017)
Summary: In patients hospitalized with acute heart failure, temporary serelaxin infusion reduced 6-month mortality through unknown mechanisms. This study therefore explored the cardiovascular effects of temporary serelaxin administration in mice subj
Externí odkaz:
https://doaj.org/article/c518624d4d9b48598e66f09100889075
Autor:
Howard H. Chen, Zehedina Khatun, Lan Wei, Choukri Mekkaoui, Dakshesh Patel, Sally Ji Who Kim, Asma Boukhalfa, Efosa Enoma, Lin Meng, Yinching I. Chen, Leena Kaikkonen, Guoping Li, Diane E. Capen, Parul Sahu, Anand T. N. Kumar, Robert M. Blanton, Hushan Yuan, Saumya Das, Lee Josephson, David E. Sosnovik
Publikováno v:
Nature Biomedical Engineering. 6:1045-1056
Autophagy-the lysosomal degradation of cytoplasmic components via their sequestration into double-membraned autophagosomes-has not been detected non-invasively. Here we show that the flux of autophagosomes can be measured via magnetic resonance imagi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::357dff3266dde2f0c299831dee54d445
https://doi.org/10.1038/s41551-022-00904-3
https://doi.org/10.1038/s41551-022-00904-3
Autor:
Michelle A. Schorn, Peter A. Jordan, Sheila Podell, Jessica M. Blanton, Vinayak Agarwal, Jason S. Biggs, Eric E. Allen, Bradley S. Moore
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT Marine sponges are recognized as valuable sources of bioactive metabolites and renowned as petri dishes of the sea, providing specialized niches for many symbiotic microorganisms. Sponges of the family Dysideidae are well documented to be ch
Externí odkaz:
https://doaj.org/article/53894f45b705493bbfe838c6d6acb2f3
Autor:
Yali Zhang, Charles M Welzig, Marian Haburcak, Bo Wang, Mark Aronovitz, Robert M Blanton, Ho-Jin Park, Thomas Force, Sami Noujaim, Jonas B Galper
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0215213 (2019)
Type 1 diabetic Akita mice develop severe cardiac parasympathetic dysfunction that we have previously demonstrated is due at least in part to an abnormality in the response of the end organ to parasympathetic stimulation. Specifically, we had shown t
Externí odkaz:
https://doaj.org/article/5393d2bb7fac46158c9180e8cbfa1b7e