Protein Kinase C Epsilon Cooperates with PTEN Loss for Prostate Tumorigenesis through the CXCL13-CXCR5 Pathway

Autor: Rachana Garg, Jorge M. Blando, Carlos J. Perez, Martin C. Abba, Fernando Benavides, Marcelo G. Kazanietz

Publikováno v: Cell Reports, Vol 19, Iss 2, Pp 375-388 (2017)

Summary: PKCε, an oncogenic member of the PKC family, is aberrantly overexpressed in epithelial cancers. To date, little is known about functional interactions of PKCε with other genetic alterations, as well as the effectors contributing to its tum

Externí odkaz: https://doaj.org/article/4816a2556646420e8ca42d9414d70505

Cooperation between Stat3 and Akt Signaling Leads to Prostate Tumor Development in Transgenic Mice

Autor: Jorge M. Blando, Steve Carbajal, Erika Abel, Linda Beltran, Claudio Conti, Susan Fischer, John DiGiovanni

Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 13, Iss 3, Pp 254-265 (2011)

In this report, we describe the development of a transgenic mouse in which a rat probasin promoter (ARR2Pb) was used to direct prostate specific expression of a constitutively active form of signal transducer and activator of transcription 3 (i.e., S

Externí odkaz: https://doaj.org/article/df6b0c52667e4be38fd1b4e7b0916c66

Preliminary Assessment of Legacy and Current-Use Pesticides in Franciscana Dolphins from Argentina

Autor: M. Gerpe, María Belén Romero, Sandra Karina Medici, M Blando, P. Polizzi, L. Chiodi

Publikováno v: Bulletin of Environmental Contamination and Toxicology. 101:14-19

The change towards intensive agriculture has led to an increase in the use of pesticides. In addition, legacy pesticides, such as organochlorines are still present in the environment. Ten Franciscana dolphins were accidentally killed by netting in a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7797ed866855eaba5d44a3ce8d6d6feb
https://doi.org/10.1007/s00128-018-2352-2

Randomized, open-label, perioperative phase II study evaluating nivolumab alone or nivolumab plus ipilimumab in patients with resectable HCC

Autor: Ahmed Omar Kaseb, Roberto Carmagnani Pestana, Luis M. Vence, Jorge M. Blando, Shalini Singh, Naruhiko Ikoma, Kanwal Pratap Singh Raghav, Divya Sakamuri, Lauren Girard, Dongfeng Tan, Jean-Nicolas Vauthey, Ching-Wei David Tzeng, Thomas A. Aloia, Yun Shin Chun, James C. Yao, Robert A. Wolff, James Patrick Allison, Padmanee Sharma

Publikováno v: Journal of Clinical Oncology. 37:4098-4098

4098 Background: In HCC, surgical resection is associated with high recurrence rate, and no effective neoadjuvant or adjuvant therapies currently exist. On the basis of of previous reports on the efficacy and safety of anti–PD-1 (nivolumab) and ant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2ca3217e504885367d0640272f61a9a7
https://doi.org/10.1200/jco.2019.37.15_suppl.4098

Attività antiossidante di una bevanda fermentata di frutti di Prunus mahaleb

Autor: Gerardi C. Tristezza M. Blando F., Mita G, Grieco F.

Publikováno v: Workshop "Nuovi scenari nell'industria agroalimentare: gli Alimenti Funzionali e Nutraceutici", Milano, Italy, 14/10/2015
info:cnr-pdr/source/autori:Gerardi C. Tristezza M. Blando F., Mita G, Grieco F./congresso_nome:Workshop "Nuovi scenari nell'industria agroalimentare: gli Alimenti Funzionali e Nutraceutici"/congresso_luogo:Milano, Italy/congresso_data:14%2F10%2F2015/anno:2015/pagina_da:/pagina_a:/intervallo_pagine

Numerose evidenze scientifiche incoraggiano il consumo di frutta e verdura per prevenire malattie cardiovascolari e tumori. Tuttavia il loro consumo rimane sotto il limite consigliato dall'Organizzazione Mondiale della Sanità. Per questo motivo i co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::c867a34a5ee144db65517e941ff73268
http://www.nutrheff.cnr.it/?p=1086