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Autor: Anders Castor, Erik Forestier, M Behrendtz, Jonas Abrahamsson, Dra Uges, Gudmar Lönnerholm, S.S.N. de Graaf, Petra C. Koopmans, Britt-Marie Frost

Publikováno v: Acta Paediatrica, 92, 551-7
Acta Paediatrica, 92(5), 551-557. Wiley
Acta Paediatrica, 92, 5, pp. 551-7

Item does not contain fulltext AIM: To investigate whether there is any pharmacokinetic rationale for the common practice of administering vincristine to adolescents at relatively lower doses than those to younger children. METHODS: A total of 98 chi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::693e5411a5f39af2934e4555ccac3153
https://hdl.handle.net/11370/c9ca174f-5710-449a-91e5-3262a71f359a

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Pharmacokinetics of doxorubicin in children with acute lymphoblastic leukemia: Multi-institutional collaborative study

Autor: S. Eksborg, Anders Castor, O. Bjork, Britt-Marie Frost, M Behrendtz, Gudmar Lönnerholm, Erik Forestier, Jonas Abrahamsson

Publikováno v: Medical and Pediatric Oncology. 38:329-337

Background, In adults, it has been shown that the pharmacokinetics of doxorubicin are highly variable, despite standardization of the dose based on body surface area (BSA). The purpose of this study was to determine the plasma concentrations of doxor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1bf707d05d3e3bbff0e6d7ec33832787
https://doi.org/10.1002/mpo.10052

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Deletions of IKZF1 and SPRED1 are associated with poor prognosis in a population-based series of pediatric B-cell precursor acute lymphoblastic leukemia diagnosed between 1992 and 2011

Autor: Kajsa Paulsson, Bertil Johansson, Andrea Biloglav, Anders Castor, M Behrendtz, Erik Forestier, Linda Olsson

Publikováno v: Leukemia; 28(2), pp 302-310 (2014)

Despite the favorable prognosis of childhood acute lymphoblastic leukemia (ALL), a substantial subset of patients relapses. Since this occurs not only in the high risk but also in the standard/intermediate groups, the presently used risk stratificati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c0e70d836dd82d220b66419a0ebf52a
https://lup.lub.lu.se/record/3956230

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Whole-exome sequencing of pediatric acute lymphoblastic leukemia

Autor: M Behrendtz, Marianne Rissler, Henrik Lilljebjörn, Carin Lassen, Felix Mitelman, Thoas Fioretos, Bertil Johansson, Jesper Heldrup

Publikováno v: Leukemia; 26, pp 1602-1607 (2012)

Acute lymphoblastic leukemia (ALL), the most common malignant disorder in childhood, is typically associated with numerical chromosomal aberrations, fusion genes or small focal deletions, thought to represent important pathogenetic events in the deve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7983d438a1ae170023cb55c197de4fb
https://lup.lub.lu.se/record/2220651

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Microarray-based classification of a consecutive series of 121 childhood acute leukemias: prediction of leukemic and genetic subtype as well as of minimal residual disease status

Autor: Anna Andersson, Johan Råde, Magnus Fontes, Bertil Johansson, Cecilia Ritz, M Behrendtz, Patrik Edén, Mattias Höglund, David Lindgren, A Porwit-Macdonald, Carin Lassen, Thoas Fioretos, Tor Olofsson, Jesper Heldrup

Publikováno v: Leukemia. 21(6)

Gene expression analyses were performed on 121 consecutive childhood leukemias (87 B-lineage acute lymphoblastic leukemias (ALLs), 11 T-cell ALLs and 23 acute myeloid leukemias (AMLs)), investigated during an 8-year period at a single center. The sup

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59e5d73773d8317b97f18f47114eb320
https://pubmed.ncbi.nlm.nih.gov/17410184

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Vincristine in childhood leukaemia: no pharmacokinetic rationale for dose reduction in adolescents

Autor: B M, Frost, G, Lönnerholm, P, Koopmans, J, Abrahamsson, M, Behrendtz, A, Castor, E, Forestier, D R A, Uges, S S N, de Graaf

Publikováno v: Acta paediatrica (Oslo, Norway : 1992). 92(5)

To investigate whether there is any pharmacokinetic rationale for the common practice of administering vincristine to adolescents at relatively lower doses than those to younger children.A total of 98 children, aged 1.3-17.3 y, with acute lymphoblast

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c5fe6704981863a24468439b5a76e782
https://pubmed.ncbi.nlm.nih.gov/12839283

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Pharmacokinetics of doxorubicin in children with acute lymphoblastic leukemia: multi-institutional collaborative study

Autor: B-M, Frost, S, Eksborg, O, Björk, J, Abrahamsson, M, Behrendtz, A, Castor, E, Forestier, G, Lönnerholm

Publikováno v: Medical and pediatric oncology. 38(5)

In adults, it has been shown that the pharmacokinetics of doxorubicin are highly variable, despite standardization of the dose based on body surface area (BSA). The purpose of this study was to determine the plasma concentrations of doxorubicin and i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6343b518bba68f292fec5f3803e13091
https://pubmed.ncbi.nlm.nih.gov/11979457

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Akademický článek

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Akademický článek

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