Zobrazeno 1 - 10
of 143
pro vyhledávání: '"M Bayssas"'
Publikováno v:
International Journal of Pharmaceutics. 242:243-246
Oxaliplatin loaded PLAGA microspheres have been prepared by solvent extraction process. Parameters affecting the release kinetics in vitro have been studied in order to design specific release profiles suitable for direct intra-tumoral injection. By
Autor:
E Dondè, P Tredici, Giovanni Tredici, Claudio Minoia, Paola Marmiroli, Petruccioli Mg, G Griffon Etienne, M Bayssas, Anna Ronchi, Guido Cavaletti
Publikováno v:
European Journal of Cancer. 37:2457-2463
The aim of this study was to determine the influence of oxaliplatin scheduling on the onset of peripheral neurotoxicity and ototoxicity in a rat model. Animals were treated with four different schedules of oxaliplatin using two cumulative doses (36 a
Autor:
Stan B. Kaye, Jaap Verweij, Jantien Wanders, H. R. Franklin, A. M. Prove, William P. Steward, M. Alakl, W.W. ten Bokkel Huinink, Michel Clavel, M. Bayssas, Martine Piccart, Thomas Tursz
Publikováno v:
Annals of Oncology. 5:527-532
Summary Background Docetaxel, a semisynthetic analog of paclitaxel, made for the needles of the European yew, Taxus baccata, is a potentially important chemotherapeutic agent for the treatment of cancer. Patients and methods In a phase II study patie
Autor:
Robert Paridaens, P.H.M. de Mulder, Jaap Verweij, U. Bruntsch, B. Heinrich, M. Bayssas, S. B. Kaye, J. Wanders, H. R. Franklin, Jan B. Vermorken, A. van Oosterom
Publikováno v:
European journal of cancer
Docetaxel (Taxotere), an analogue of paclitaxel, was tested in a phase II study in advanced renal cell carcinoma. Consenting patients with measurable lesions, adequate organ functions and no prior chemotherapy received 100 mg/m2 of docetaxel as a 1-h
Publikováno v:
International journal of pharmaceutics. 242(1-2)
Oxaliplatin loaded PLAGA microspheres have been prepared by solvent extraction process. Parameters affecting the release kinetics in vitro have been studied in order to design specific release profiles suitable for direct intra-tumoral injection. By
Autor:
Martin Gore, Jantien Wanders, Allan T. van Oosterom, Wim W. ten Bokkel Huinink, Stan B. Kaye, M. Bayssas, Jaap Verweij, Martine Piccart, Hilary Frankli
Publikováno v:
Journal of the National Cancer Institute
BACKGROUND: Because of the relative scarcity of natural paclitaxel (Taxol), which has been recently recognized as a highly cytotoxic agent for use in platinum-refractory ovarian cancer, synthetic and semisynthetic substitutes have been actively pursu
Autor:
N. Azli, Véronique Diéras, B. Chevallier, Pierre Kerbrat, M. van Glabbeke, M. Bayssas, P. Fumoleau
Publikováno v:
Breast cancer research and treatment. 33(1)
Therapy for advanced breast cancer has not improved significantly in recent years, remaining strictly palliative in nature and intent. One approach to increase the effectiveness of the treatment is the introduction of active new drugs. Taxotere® (do
Autor:
Chantal Fossat, M. Bayssas, I. Juhan Vague, Patrice Viens, D. Baume, Danielle Sainty, Dominique Maraninchi, A. M. Stoppa, Didier Blaise
Publikováno v:
British journal of haematology. 83(1)
Autor:
Robert A. Newman, M. Bayssas, Richard Pazdur, Beth Bready, Franzanne Vreeland, Angela Fuentes, John A. Benvenuto, Martin N. Raber, Beverly M. Newman, Dennis Moore, Ishmael Jaiyesimi
Publikováno v:
Journal of the National Cancer Institute. 84(23)
Background Taxotere, a semisynthetic compound structurally related to taxol, has a broad spectrum of activity in murine transplantable tumors; in the B16 melanoma model, it caused a total log cell kill 2.5 times greater than that caused by taxol at e
Autor:
Giovanni Tredici, Claudio Minoia, Paola Marmiroli, E Dondè, A Gatti, Petruccioli Mg, M Bayssas, G Griffon Etienne, P Tredici, G Cavaletti
Publikováno v:
Journal of the Peripheral Nervous System. 6:44-44
The dose-limiting side effect of the second-generation platinum drug oxaliplatin is peripheral neurotoxicity. In the present study we compared the effect on the peripheral nervous system and on the auditory pathway of the rat of four different schedu