Výsledky vyhledávání

Persistent mismatch repair deficiency following targeted correction of hMLH1

Autor: Michele Vitolo, Giancarlo Marra, Ben Ho Park, Kurtis E. Bachman, Katja Baerenfaller, M B Weiss

Publikováno v: Cancer Gene Therapy. 14:98-104

The use of gene therapy to correct mutated or lost gene function for the treatment of human cancers has been an active, yet problematic area of biomedical research. Many technical difficulties, including efficient tissue-specific delivery, integratio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c886d0937cfb2c3155791b39e6e7dc5c
https://doi.org/10.1038/sj.cgt.7700997

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Deletion of p53 in human mammary epithelial cells causes chromosomal instability and altered therapeutic response

Autor: David J. Weber, Samuel R. Denmeade, D M Rosen, Morassa Mohseni, Kurtis E. Bachman, M B Weiss, Michele Vitolo, Ben Ho Park

Publikováno v: Oncogene. 29(33)

The TP53 tumor suppressor gene is the most commonly mutated gene in human cancers. To evaluate the biological and clinical relevance of p53 loss, human somatic cell gene targeting was used to delete the TP53 gene in the non-tumorigenic epithelial cel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3f34b03a1060a52e7b7d2c5b8a19ee0
https://pubmed.ncbi.nlm.nih.gov/20562907

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Percutaneous transluminal coronary angioplasty (PTCA) combined with stenting improves clinical outcomes compared with PTCA alone in acute myocardial infarction

Autor: S, Koneru, C E, Monsen, A, Pucillo, M B, Cohen, J, McClung, M B, Weiss

Publikováno v: Heart disease (Hagerstown, Md.). 2(4)

Balloon angioplasty in acute myocardial infarction is an established procedure. The procedure is limited by the potential for early abrupt reocclusion (18-20%) and other complications. Coronary stenting improves the initial success rate, decreases th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fe734782617e6e4ce9c84e902f716c52
https://pubmed.ncbi.nlm.nih.gov/11728270

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Long-term clinical outcome of stenting in primary and rescue angioplasty in acute myocardial infarction

Autor: M T, Javed, S, Dhakam, S, Koneru, A, Pucillo, C, Monsen, M B, Cohen, M B, Weiss

Publikováno v: Heart disease (Hagerstown, Md.). 1(2)

Long-term clinical outcome after use of stents in primary and rescue coronary angioplasty for treatment of acute myocardial infarction has not been described in detail. This study was conducted to evaluate long-term (more than one year) outcome in pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::60d82697e4da6e4d926beb3f282ca4da
https://pubmed.ncbi.nlm.nih.gov/11720605

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Adverse effects of enalapril in the Studies of Left Ventricular Dysfunction (SOLVD). SOLVD Investigators

Autor: J B, Kostis, B, Shelton, G, Gosselin, C, Goulet, W B, Hood, R M, Kohn, S H, Kubo, E, Schron, M B, Weiss, P W, Willis, J B, Young, J, Probstfield

Publikováno v: American heart journal. 131(2)

In the Studies of Left Ventricular Dysfunction (LVD), enalapril or placebo was administered in a double-blind fashion to 6797 participants with ejection fractionor = 0.35. During 40 months' average follow-up, 28.1% of participants randomized to enala

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6769b9fc0d19330c8efdcebf701409ea
https://pubmed.ncbi.nlm.nih.gov/8579032

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Adjunctive thrombolytic therapy during angioplasty for ischemic rest angina. Results of the TAUSA Trial. TAUSA Investigators. Thrombolysis and Angioplasty in Unstable Angina trial

Autor: John A. Ambrose, Douglas H. Israel, R K Myler, C E Hjemdahl-Monsen, Samin K. Sharma, Orlandino D. Almeida, Denise E. Ratner, Jonathan D. Marmur, Sabino Torre, M B Weiss

Publikováno v: Circulation. 90(1)

BACKGROUND Acute closure is increased after angioplasty in unstable angina, and adjunctive intracoronary thrombolytic therapy has been used successfully to increase angiographic success. The role of prophylactic thrombolytic therapy during angioplast

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0910fc494ca7128c372f2433863f4f7
https://pubmed.ncbi.nlm.nih.gov/8026054

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The human sinus node electrogram: a transvenous catheter technique and a comparison of directly measured and indirectly estimated sinoatrial conduction time in adults

Autor: Bigger Jt, J.C. Davis, J N Patton, M B Weiss, Jerry Gliklich, James A. Reiffel, Eli S. Gang

Publikováno v: Circulation. 62:1324-1334

To improve methods for evaluating human sinus node function (SNF), we developed a transvenous electrode catheter technique for direct recording of sinus node electrograms in adults. Sinus node electrograms (SNE) characterized by low-frequency, anatom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3912ce52e6f2dce0ad3f7dc80a4e86f
https://doi.org/10.1161/01.cir.62.6.1324

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