Zobrazeno 1 - 10
of 144
pro vyhledávání: '"M B Sporn"'
Publikováno v:
Journal of Lipid Research, Vol 19, Iss 1, Pp 32-37 (1978)
A reverse phase high-pressure liquid chromatography system for rapid separation of various retinoids (vitamin A and its analogs) with little or no degradation is described. This method permits detection of as little as 22 pmol of retinoic acid. The p
Externí odkaz:
https://doaj.org/article/94e5bfa145144e7994d7a926873fb160
Publikováno v:
Osteoarthritis and cartilage. 20(5)
Novel methods for inducing chondrogenesis are critical for cartilage tissue engineering and regeneration. Here we show that the synthetic oleanane triterpenoids, CDDO-Imidazolide (CDDO-Im) and CDDO-Ethyl amide (CDDO-EA), at concentrations as low as 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8c8801c9c29ac2dec2f932ca28a46812
https://pubmed.ncbi.nlm.nih.gov/32471658
https://pubmed.ncbi.nlm.nih.gov/32471658
Publikováno v:
Stroke. 24:558-562
The aim of this study was to examine the effect of transforming growth factor-beta 1, a cytokine shown to amelioriate cardiac ischemia, in a rabbit model of thromboembolic stroke. An autologous clot embolus was introduced intracranially through the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed188fbacf1d2aa25a9a0a4d69b1f51
https://doi.org/10.1161/01.str.24.4.558
https://doi.org/10.1161/01.str.24.4.558
Publikováno v:
Endocrinology. 132:1745-1749
The mechanism of signal transduction by transforming growth factor-beta 1 (TGF-beta 1) is largely unknown. In this study, TGF-beta 1 was able to stimulate 45Ca2+ uptake in cultured rat Sertoli cells. In contrast to the rapid stimulation of 45Ca2+ upt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43f2f7b70879d397d7a3d3de1472967b
https://doi.org/10.1210/endo.132.4.8462475
https://doi.org/10.1210/endo.132.4.8462475
Publikováno v:
Molecular and Cellular Biology. 11:3795-3803
Transforming growth factor-beta 3 (TGF-beta 3) mRNA is differentially expressed in developing and mature mouse tissues, including high-level expression in developing and adult cardiac tissue. We show now that TGF-beta 3 mRNA is also expressed highly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b13912fcf0b427c016af7eb1ed81953
https://doi.org/10.1128/mcb.11.7.3795
https://doi.org/10.1128/mcb.11.7.3795
Autor:
F. V. Howell, David Danielpour, K. E P Van Roozendaal, S. R. Ebbs, M. Baum, Anthony A. Colletta, L. M. Wakefield, M. B. Sporn
Publikováno v:
British Journal of Cancer
The clinical use of anti-oestrogens in breast cancer therapy has traditionally been restricted to tumours that contain measurable oestrogen receptor protein. However, it is now widely recognised that the clinical response to adjuvant anti-oestrogen t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ffda3b8dc0a9b9b733a710d0e304091
https://doi.org/10.1038/bjc.1990.307
https://doi.org/10.1038/bjc.1990.307
Autor:
N, Suh, A L, Glasebrook, A D, Palkowitz, H U, Bryant, L L, Burris, J J, Starling, H L, Pearce, C, Williams, C, Peer, Y, Wang, M B, Sporn
Publikováno v:
Cancer research. 61(23)
Arzoxifene ([6-hydroxy-3-[4-[2-(1-piperidinyl)-ethoxy]phenoxy]-2-(4-methoxyphenyl)]benzo[b]thiophene) is a selective estrogen receptor modulator (SERM) that is a potent estrogen antagonist in mammary and uterine tissue while acting as an estrogen ago
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::24086254f36ab915ef7a017b0e76a352
https://pubmed.ncbi.nlm.nih.gov/11731420
https://pubmed.ncbi.nlm.nih.gov/11731420
Autor:
M R, Shaker, G, Yang, T L, Timme, S H, Park, D, Kadmon, C, Ren, X, Ji, H M, Lee, I, Sehgal, M, Anzano, M B, Sporn, T C, Thompson
Publikováno v:
Clinicalexperimental metastasis. 18(5)
The effects of the synthetic retinoid N-(4-hydroxyphenyl) retinamide (4-HPR) on prostate cancer metastasis in vivo were evaluated in the mouse prostate reconstitution (MPR) model. MPRs were produced by infection of either heterozygous (+/-) or nulliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4dfe382318ccf4d1ec026251eb0b4e71
https://pubmed.ncbi.nlm.nih.gov/11467776
https://pubmed.ncbi.nlm.nih.gov/11467776
Publikováno v:
Arthritis and rheumatism. 44(5)
To address the effects of a novel synthetic triterpenoid, 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid (CDDO), on the induction of matrix metalloproteinases 1 and 13 (MMP-1, MMP-13) by inflammatory cytokines.Human chondrosarcoma cells stimulated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::56f3b7826e130505064b758180d15842
https://pubmed.ncbi.nlm.nih.gov/11352241
https://pubmed.ncbi.nlm.nih.gov/11352241