Zobrazeno 1 - 10
of 30
pro vyhledávání: '"M B Spellerberg"'
Autor:
George P. Lomonossoff, Freda K. Stevenson, M B Spellerberg, Rosalind Munday, Natalia Savelyeva
Publikováno v:
Nature Biotechnology. 19:760-764
DNA delivery of tumor antigens can activate specific immune attack on cancer cells. However, antigens may be weak, and immune capacity can be compromised. Fusion of genes encoding activating sequences to the tumor antigen sequence facilitates promoti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::420db9996ab68a03af4434e2cec28cea
https://doi.org/10.1038/90816
https://doi.org/10.1038/90816
Autor:
Harry N White, Zadie Davis, Freda K. Stevenson, David Goldblatt, Helen Baxendale, M B Spellerberg
Publikováno v:
European Journal of Immunology. 30:1214-1223
Pneumococcal serotype-specific anti-capsular polysaccharide antibodies protect against invasive pneumococcal disease. Within an individual the diversity of these antibodies is limited. To evaluate the repertoire of antibodies to pneumococcus and dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::399d1425bad44dc53571b66cecd839c9
https://doi.org/10.1002/(sici)1521-4141(200004)30:4<1214::aid-immu1214>3.0.co
https://doi.org/10.1002/(sici)1521-4141(200004)30:4<1214::aid-immu1214>3.0.co
Autor:
Freda K. Stevenson, Julia Newton-Bishop, Kevin Clough, Karren Dawson, M B Spellerberg, Norman Gregson, Mark D. Melamed, Myles D. Thomas, Kathleen N. Potter, Caroline J. Chapman
Publikováno v:
Human Antibodies. 9:95-106
A heterohybridoma cell line producing the human monoclonal antibody (MoAb) MDT.1 has been established. The heavy chain of MoAb MDT.1 is encoded by the VH gene segment V4-34 (previously designated VH4-21), and the light chain is encoded by the V kappa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::60c54fd1212d606fa01c2d6b4352366a
https://doi.org/10.3233/hab-1999-9203
https://doi.org/10.3233/hab-1999-9203
Publikováno v:
Vaccine. 17:3030-3038
To gain insight into the routes of presentation of pathogen sequences via DNA vaccines, we have compared the abilities of sequences encoding fragment C of tetanus toxin (FrC) and influenza A virus nucleoprotein (NP) to induce antibody or cytotoxic T-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0ab281e21012cd51dbd465332986d04
https://doi.org/10.1016/s0264-410x(99)00171-1
https://doi.org/10.1016/s0264-410x(99)00171-1
Publikováno v:
The Journal of Immunology. 159:1885-1892
Idiotypic determinants can act as tumor-associated Ags for B cell lymphoma. Vaccination with idiotypic protein and adjuvant is known to induce specific protection against lymphoma challenge in mice, largely mediated by anti-idiotypic Ab. For facilita
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37cec739482abd0f232b1c643c088269
https://doi.org/10.4049/jimmunol.159.4.1885
https://doi.org/10.4049/jimmunol.159.4.1885
Autor:
Andrew R. Thompsett, Delin Zhu, M B Spellerberg, Terry J. Hamblin, Freda K. Stevenson, Catherine A. King
Publikováno v:
Biochemical Society Transactions. 25:743-747
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dcd3664254f8618c2e331c4cb877f79
https://doi.org/10.1042/bst0250743
https://doi.org/10.1042/bst0250743
Publikováno v:
Human Antibodies. 6:52-56
The VH4-21 (V4-34) gene segment, a member of the VH4 family, is expressed early in B-cell maturation and is utilized by approximately 6% of normal adult B lymphocytes. This prevalence indicates an importance of VH4-21 in the B-cell repertoire. The ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea3f2d79fd1555e25665cd9ec5b23304
https://doi.org/10.3233/hab-1995-6203
https://doi.org/10.3233/hab-1995-6203
Publikováno v:
Vox Sanguinis. 68:231-235
Most autoanti-red cell antibodies found in patients with cold agglutinin disease are specific for the I or i carbohydrate antigenic determinants. However, antibodies specific for other antigens such as Pr or Sa can also be found, and these are identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e59f7f46d3e510ebfa7152851441d64
https://doi.org/10.1111/j.1423-0410.1995.tb02578.x
https://doi.org/10.1111/j.1423-0410.1995.tb02578.x
Publikováno v:
Leukemia & Lymphoma. 16:379-385
Selection of immunoglobulin variable region genes for recombination in B cells takes place from among those VH and VL gene segments available in the unrearranged germ line repertoire. In the case of neoplastic B cells, there is apparent deviation in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b90959c18e8be0d6636ef28f8cf4cc72
https://doi.org/10.3109/10428199509054423
https://doi.org/10.3109/10428199509054423
Autor:
Chellia T. Ravirajan, David S. Latchman, Caroline J. Chapman, D.A. Isenberg, Celia Longhurst, Freda K. Stevenson, Terry J. Hamblin, Michael Ehrenstein, M B Spellerberg
Publikováno v:
Journal of Autoimmunity. 6:809-825
A monoclonal antibody (9G4) which detects an idiotope (Id) rising from heavy chains encoded by the VH4-21 gene segment has been utilized to investigate the role of this gene in encoding anti-DNA antibodies in SLE. Two hybridomas secreting Id-positive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54623a7676719cdc4bfa6b5a7ab45fc1
https://doi.org/10.1006/jaut.1993.1066
https://doi.org/10.1006/jaut.1993.1066