Výsledky vyhledávání

Akademický článek

Glycerol Kinase Drives Hepatic de novo Lipogenesis and Triglyceride Synthesis in Nonalcoholic Fatty Liver by Activating SREBP‐1c Transcription, Upregulating DGAT1/2 Expression, and Promoting Glycerol Metabolism.

Autor: Ouyang, Shuyu¹ (AUTHOR), Zhuo, Shu¹ (AUTHOR), Yang, Mengmei¹ (AUTHOR), Zhu, Tengfei² (AUTHOR), Yu, Shuting¹ (AUTHOR), Li, Yu¹ (AUTHOR), Ying, Hao¹ (AUTHOR), Le, Yingying¹ (AUTHOR) yyle@sinh.ac.cn

Publikováno v: Advanced Science. 12/11/2024, Vol. 11 Issue 46, p1-18. 18p.

Zobrazit plný text záznamu

Plný text ve formátu HTML

Increased hepatic VLDL secretion, lipogenesis, and SREBP-1 expression in the corpulent JCR:LA-cp rat

Autor: M B, Elam, H G, Wilcox, L M, Cagen, X, Deng, R, Raghow, P, Kumar, M, Heimberg, J C, Russell

Publikováno v: Journal of lipid research. 42(12)

The corpulent JCR:LA-cp rat (cp/cp) is a useful model for study of the metabolic consequences of obesity and hyperinsulinemia. To assess the effect of hyperinsulinemia on VLDL secretion in this model, we measured rates of secretion of VLDL in perfuse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e341a9a0f507e2e3ca21c49472d3607a
https://pubmed.ncbi.nlm.nih.gov/11734577

Zobrazit plný text záznamu

Effect of niacin on lipid and lipoprotein levels and glycemic control in patients with diabetes and peripheral arterial disease: the ADMIT study: A randomized trial. Arterial Disease Multiple Intervention Trial

Autor: M B, Elam, D B, Hunninghake, K B, Davis, R, Garg, C, Johnson, D, Egan, J B, Kostis, D S, Sheps, E A, Brinton

Publikováno v: JAMA. 284(10)

Although niacin increases low levels of high-density lipoprotein cholesterol (HDL-C), which frequently accompany diabetes, current guidelines do not recommend use of niacin in patients with diabetes because of concerns about adverse effects on glycem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9f6773ef38869e0442bc563c5cdb3bbc
https://pubmed.ncbi.nlm.nih.gov/10979113

Zobrazit plný text záznamu

Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group

Autor: H B, Rubins, S J, Robins, D, Collins, C L, Fye, J W, Anderson, M B, Elam, F H, Faas, E, Linares, E J, Schaefer, G, Schectman, T J, Wilt, J, Wittes

Publikováno v: The New England journal of medicine. 341(6)

Although it is generally accepted that lowering elevated serum levels of low-density lipoprotein (LDL) cholesterol in patients with coronary heart disease is beneficial, there are few data to guide decisions about therapy for patients whose primary l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0d2d14bf27049d3c9340b82505e6c9cd
https://pubmed.ncbi.nlm.nih.gov/10438259

Zobrazit plný text záznamu

Distribution of lipids in 8,500 men with coronary artery disease. Department of Veterans Affairs HDL Intervention Trial Study Group

Autor: H B, Rubins, S J, Robins, D, Collins, A, Iranmanesh, T J, Wilt, D, Mann, M, Mayo-Smith, F H, Faas, M B, Elam, G H, Rutan

Publikováno v: The American journal of cardiology. 75(17)

In the present study we measured fasting lipid profiles in over 8,500 community-living men with coronary artery disease (CAD) to determine the distribution of lipid abnormalities in this population: 81% were white and 16% black; mean age 62.9 +/- 8 y

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b417ec8a8f3bb6ec7c893c81ce8d4c36
https://pubmed.ncbi.nlm.nih.gov/7778538

Zobrazit plný text záznamu

Regulation of calmodulin gene expression by insulin is both transcriptional and post-transcriptional

Autor: S S, Solomon, M R, Palazzolo, M B, Elam, S, Green, R, Raghow

Publikováno v: The Journal of laboratory and clinical medicine. 124(3)

Previously we demonstrated that in streptozotocin-induced or spontaneously diabetic BB rats (BB-SDR), low-Km cyclic AMP (cAMP), phosphodiesterase (PDE), and calmodulin (CaM) are decreased. Isolated fat cells of diabetic animals synthesized less CaM a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e2d931ac30ff4afe959a1a1f7fbaa7da
https://pubmed.ncbi.nlm.nih.gov/8083570

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání