Zobrazeno 1 - 10
of 600
pro vyhledávání: '"M B, Youdim"'
Autor:
An, Jing1 (AUTHOR), Wen, Lulu1 (AUTHOR), Yu, Haiyang1 (AUTHOR), Bu, Zhongqi1 (AUTHOR), Feng, Juan1 (AUTHOR) anj@sj‐hospital.org
Publikováno v:
CNS Neuroscience & Therapeutics. Oct2024, Vol. 30 Issue 10, p1-13. 13p.
Publikováno v:
Methods in molecular medicine. 62
ABSTRUCT: Parkinson's disease (PD) is associated with progressive degeneration of melanin-containing dopamine neuron cell bodies arising in the substantia nigra pars compacta (SNpc) and projecting terminals to the striatum. The disease is best charac
Autor:
Abu-Hassan AA; Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Al-Azhar University, Assiut Branch, Assiut, Egypt., Mahdi WA; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia., Alshehri S; Department of Pharmaceutics, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia., El Hamd MA; Department of Pharmaceutical Chemistry, College of Pharmacy, Shaqra University, Shaqra, Saudi Arabia.; Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, South Valley University, Qena, Egypt.
Publikováno v:
Luminescence : the journal of biological and chemical luminescence [Luminescence] 2024 Aug; Vol. 39 (8), pp. e4853.
Autor:
M B, Youdim, M, Weinstock
Publikováno v:
Cellular and molecular neurobiology. 21(6)
Rasagiline (N-propargyl-1-(R)-aminoindan) is a selective, irreversible monoamine oxidase B (MAO B) inhibitor which has been developed as an anti-Parkinson drug. In controlled monotherapy and as adjunct to L-dopa it has shown anti-Parkinson activity.
Publikováno v:
Journal of neurochemistry. 78(5)
In the present study we demonstrate neuroprotective property of green tea extract and (-)-epigallocatechin-3-gallate in N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mice model of Parkinson's disease. N-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine neuro
Publikováno v:
Journal of neurochemistry. 78(4)
An endogenous dopaminergic neurotoxin, N-methyl(R)salsolinol, was found to induce apoptosis in human dopaminergic SH-SY5Y cells by step-wise activation of apoptotic cascade; collapse in mitochondrial membrane potential, DeltaPsim, activation of caspa
Publikováno v:
Journal of neurochemistry. 78(1)
To establish the possible roles of oxidative stress, inflammatory processes and other unknown mechanisms in neurodegeneration, we investigated brain gene alterations in N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mice model of Parkinson's dis
Autor:
M B, Youdim
Publikováno v:
Public health reviews. 28(1-4)
Publikováno v:
Journal of neural transmission. Supplementum. (60)
In Parkinson's disease, apoptosis was proposed to cause cell death in nigral dopamine neurons. An endogenous dopaminergic neurotoxin, N-methyl(R)salsolinol, stereo-selectively induced apoptosis in human neuroblastoma SH-SY5Y cells. In this paper the
Publikováno v:
Journal of neural transmission. Supplementum. (60)
Despite physiological systems designed to achieve iron homeostasis, increased concentrations of brain iron have been demonstrated in a range of neurodegenerative diseases. These including the parkinsonian syndromes, the trinucleotide repeat disorders