Zobrazeno 1 - 10
of 56
pro vyhledávání: '"M B, Yin"'
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Cancer metastasis reviews. 20(1-2)
The common clinical problem in the successful treatment of cancer is the resistance of cancer cells to chemotherapeutic drugs. Chemotherapy kills drug-sensitive cells, but leaves behind a higher proportion of drug-resistant cells. The resistance can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7e9b59bdaa766604630cff49e8bc83dd
https://pubmed.ncbi.nlm.nih.gov/11831638
https://pubmed.ncbi.nlm.nih.gov/11831638
Publikováno v:
International journal of cancer. 83(3)
Time-dependent ladder-type DNA fragmentation and morphological alterations consistent with apoptosis were observed among A253 human head and neck squamous cell carcinoma (HNSCC) cells in nude mice from 15 to 18 days after transplantation, without any
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1978c339445eb43498419eb0236f8b92
https://pubmed.ncbi.nlm.nih.gov/10495426
https://pubmed.ncbi.nlm.nih.gov/10495426
Publikováno v:
Oncology research. 11(2)
Human head and neck squamous cell carcinoma A253 cells, which do not express p53 and p21 proteins, were engineered to stably express about 50-fold higher level of Bax protein (A253/Bax) than the mock-transfected (A253/vec) or parental cells. Using th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b50768ec1911987259b1232775189845
https://pubmed.ncbi.nlm.nih.gov/10489165
https://pubmed.ncbi.nlm.nih.gov/10489165
Publikováno v:
Anticancer research. 18(5A)
SN-38 is the active metabolite of the topoisomerase-I (topo-I) inhibitor Irinotecan (CPT-11). Generally, topo-I inhibitors stabilize the complex between topo-I and DNA which collide with moving DNA replication forks, eventually leading to double stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::25f8c71e223b7510443e51fae1506c39
https://pubmed.ncbi.nlm.nih.gov/9858931
https://pubmed.ncbi.nlm.nih.gov/9858931
Publikováno v:
Anticancer research. 17(5A)
The prognostic value of topoisomerase I (Topo I) catalytic activity and expression of the multidrug resistance (MDR) marker P-glycoprotein (Pgp) and multidrug resistance protein (MRP) for in vitro sensitivity to Topo I interactive agents were evaluat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4dbfa6084c870abd4332427f53412d9b
https://pubmed.ncbi.nlm.nih.gov/9413228
https://pubmed.ncbi.nlm.nih.gov/9413228
Publikováno v:
Oncology research. 9(9)
Membrane protein-associated alterations in cellular drug accumulation have been recently implicated in resistance to topoisomerase I (TOP-I)-interactive drugs. The present study investigated the cellular determinants of resistance to the indolocarbaz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8dbbce64eb16f6f23836774c550cc8f4
https://pubmed.ncbi.nlm.nih.gov/9495454
https://pubmed.ncbi.nlm.nih.gov/9495454
Autor:
H, Minderman, U, Vanhoefer, K, Toth, M B, Yin, M D, Minderman, C, Wrzosek, M L, Slovak, Y M, Rustum
Publikováno v:
Cytometry. 25(1)
Multidrug resistance (MDR) is often related to expression of P-glycoprotein (Pgp) or Multidrug Resistance Protein (MRP). Pgp-mediated MDR can be evaluated by determining cellular retention of fluorescent substrates by flow cytometry. This study deter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::621bc8de2d1e8305febe9c469f4d97e9
https://pubmed.ncbi.nlm.nih.gov/8875050
https://pubmed.ncbi.nlm.nih.gov/8875050
Publikováno v:
Oncology research. 7(2)
The patterns of DNA fragmentation were evaluated following a brief exposure (2 h) of the human ileocecal adenocarcinoma cell line, HCT-8, to several specific thymidylate synthase inhibitors, a quinazoline (ZD1694) and benz[cd]indole-containing molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f319a0e024fa21202114fab88b00dda5
https://pubmed.ncbi.nlm.nih.gov/7579730
https://pubmed.ncbi.nlm.nih.gov/7579730
Publikováno v:
Cancer research. 52(21)
DNA single-strand breaks and associated growth inhibition induced by the thymidylate synthase inhibitor N-(5-[N-(3,4-dihydro-2-methyl-4-oxoquinazoline-6-ylmethyl)-N -methylamino]-2 - thenoyl)-L-glutamic acid (ICI D1694) were quantitated using the hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dcdcba59f8e31e4bfebc6aa1e99e3f1f
https://pubmed.ncbi.nlm.nih.gov/1394217
https://pubmed.ncbi.nlm.nih.gov/1394217