Výsledky vyhledávání - "M B, Prystowsky"

Regulation of cAMP-responsive enhancer binding proteins during cell cycle progression in T lymphocytes stimulated by IL-2

Autor: N Feuerstein, D Huang, S H Hinrichs, D J Orten, N Aiyar, M B Prystowsky

Publikováno v: The Journal of Immunology. 154:68-79

IL-2 stimulates the proliferative response of various lymphoid cells. Previous studies showed an increase in intracellular levels of cAMP concomitant with an increase in phosphorylation of discrete proteins by protein kinase A at late G1 phase in mit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d4b1ef7dc20f9dfec08208b621972a32
https://doi.org/10.4049/jimmunol.154.1.68

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Differential effects of monoclonal antibodies on activating transcription factor-1 and cAMP response element binding protein interactions with DNA

Autor: Steven H. Hinrichs, Judith M. Strawhecker, D. Huang, Sam D. Sanderson, Dana J. Orten, M. B. Prystowsky

Publikováno v: Journal of Biological Chemistry. 269:32254-32263

Activating transcription factor-1 (ATF1) and cAMP response element binding protein (CREB) have been implicated in cAMP-, calcium-, and virus-induced transcriptional alterations. Although CREB and ATF1 share extensive homology, they appear to mediate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::acff36951e9325d75757448810a2df7d
https://doi.org/10.1016/s0021-9258(18)31629-6

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Selective induction of the beta chemokine C10 by IL-4 in mouse macrophages

Autor: A Orlofsky, E Y Lin, M B Prystowsky

Publikováno v: The Journal of Immunology. 152:5084-5091

The beta chemokines are a family of 8- to 12-kDa leukocyte chemoattractants that are typically produced by activated macrophages or lymphocytes. We examined the expression in primary macrophages of a recently described, and as yet functionally unchar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1f796f6256727a2bb68b9afc51034d26
https://doi.org/10.4049/jimmunol.152.10.5084

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Characterization of A1, a novel hemopoietic-specific early-response gene with sequence similarity to bcl-2

Autor: E Y Lin, A Orlofsky, M S Berger, M B Prystowsky

Publikováno v: The Journal of Immunology. 151:1979-1988

Granulocyte-macrophage colony-stimulating factor (GM-CSF) stimulates hemopoietic cell proliferation, differentiation, and functional activation by inducing the expression of specific genes. As part of an investigation of the regulation of gene expres

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0855a404214745ecf7c0875f49e29beb
https://doi.org/10.4049/jimmunol.151.4.1979

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The murine antiapoptotic protein A1 is induced in inflammatory macrophages and constitutively expressed in neutrophils

Autor: A, Orlofsky, R D, Somogyi, L M, Weiss, M B, Prystowsky

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 163(1)

Myeloid leukocytes are thought to regulate their susceptibility to apoptosis upon migration to a site of inflammation. However, factors that determine survival have not been well characterized in these cells. We have examined the expression of murine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::530acb0e88c92a130d2c6ee94861edbf
https://pubmed.ncbi.nlm.nih.gov/10384143

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Isolation and analysis of a T cell clone variant exhibiting constitutively phosphorylated Ser133 cAMP response element-binding protein

Autor: S M, Belkowski, C S, Rubin, M B, Prystowsky

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 161(2)

In driving T cell proliferation, IL-2 stimulates a new program of gene expression that includes proliferating cell nuclear antigen (PCNA), a requisite processivity factor for DNA polymerase delta. PCNA transcription is regulated in part through tande

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6c7f2a20f52f3401900489903c8752a1
https://pubmed.ncbi.nlm.nih.gov/9670940

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A1, a Bcl-2 family member, prolongs cell survival and permits myeloid differentiation

Autor: E Y, Lin, A, Orlofsky, H G, Wang, J C, Reed, M B, Prystowsky

Publikováno v: Blood. 87(3)

A1, a bcl-2 family member, has been identified as a hematopoietic-specific, early inducible gene. In this study it is shown that stable transfection of A1 into an interleukin-3 (IL-3)-dependent myeloid precursor cell line, 32D c13, leads to a retarda

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::eee1cf4a97e872901f11f9f888ebc445
https://pubmed.ncbi.nlm.nih.gov/8562970

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Rapamycin selectively blocks interleukin-2-induced proliferating cell nuclear antigen gene expression in T lymphocyte. Evidence for inhibition of CREB/ATF binding activities

Autor: N, Feuerstein, D, Huang, M B, Prystowsky

Publikováno v: The Journal of biological chemistry. 270(16)

The macrolide rapamycin arrests T lymphocytes stimulated by interleukin-2 (IL-2) at G1/S. We have recently found that IL-2 induced an increase in the binding of discrete transcription factors of the ATF/cAMP-responsive element binding factor (CREB) f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0742bc0c8f3adf457296d1e2fe743432
https://pubmed.ncbi.nlm.nih.gov/7721872

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Regulation of cAMP-responsive enhancer binding proteins during cell cycle progression in T lymphocytes stimulated by IL-2

Autor: N, Feuerstein, D, Huang, S H, Hinrichs, D J, Orten, N, Aiyar, M B, Prystowsky

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 154(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6eed76dd2f48cacb78fce7b7493bd11a
https://pubmed.ncbi.nlm.nih.gov/7995960

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