Zobrazeno 1 - 10
of 135
pro vyhledávání: '"M B, Oldstone"'
Publikováno v:
The Journal of Immunology. 157:3396-3403
CTL play a critical role in immune defense by recognizing and killing virally infected or tumor cells. In this report, the structure of cytoplasm within living CTL was monitored during CTL killing of target cells. Living CTL were simultaneously loade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e19d2f3bb0e8cceaf2a41405fce7b961
https://doi.org/10.4049/jimmunol.157.8.3396
https://doi.org/10.4049/jimmunol.157.8.3396
Publikováno v:
The Journal of Immunology. 154:5582-5589
Simian immunodeficiency virus (SIV)-specific CD8+ CTL were isolated from blood, cerebrospinal fluid, and brains of rhesus macaques infected i.v. with SIV. CTL were found as early as 1 wk postinfection and their appearance correlated with a decrease o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5c3289f1157a96ac0bd56b86d0c1789
https://doi.org/10.4049/jimmunol.154.10.5582
https://doi.org/10.4049/jimmunol.154.10.5582
Publikováno v:
The Journal of Immunology. 152:716-723
The simultaneous expression of multiple cytokine genes was examined within the brain and peripheral organs of euthymic and congenic athymic mice during the course of lymphocytic choriomeningitis (LCM) induced by the intracranial inoculation of LCM vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d01e495475c8d6ca86814b18d7c6f2c0
https://doi.org/10.4049/jimmunol.152.2.716
https://doi.org/10.4049/jimmunol.152.2.716
Publikováno v:
The Journal of Experimental Medicine
Observations based on elution of IgG from nephritic kidneys of NZ mice and absorption of the eluted IgG with selected antigens indicate that their immune complex nephritis involves at least two kinds of antigen-antibody complexes. Antibodies reactive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::106879e37dd80bcba1b5a291de3bc67f
https://pubmed.ncbi.nlm.nih.gov/19867382
https://pubmed.ncbi.nlm.nih.gov/19867382
Publikováno v:
The Journal of clinical investigation. 108(12)
To analyze the function of the Th1-promoting cytokine IL-12 in vivo, we generated transgenic (tg) mice (RIP-IL12 mice) whose pancreatic beta cells constitutively express bioactive IL-12 or one of its components, p35 or p40. In contrast to non-tg litt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d0840424f9267ce52b5bb818c4f2242
https://pubmed.ncbi.nlm.nih.gov/11748258
https://pubmed.ncbi.nlm.nih.gov/11748258
Autor:
D, Hudrisier, J, Riond, O, Burlet-Schiltz, M G, von Herrath, H, Lewicki, B, Monsarrat, M B, Oldstone, J E, Gairin
Publikováno v:
The Journal of biological chemistry. 276(22)
Structural similarity (molecular mimicry) between viral epitopes and self-peptides can lead to the induction of autoaggressive CD4(+) as well as CD8(+) T cell responses. Based on the flexibility of T cell receptor/antigen/major histocompatibility com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fbbd3ca6361ae8536267474536317e66
https://pubmed.ncbi.nlm.nih.gov/11278441
https://pubmed.ncbi.nlm.nih.gov/11278441
Autor:
J F, Bureau, S, Le Goff, D, Thomas, A F, Parlow, J C, de la Torre, D, Homann, M, Brahic, M B, Oldstone
Publikováno v:
Virology. 281(1)
Lymphocytic choriomeningitis virus (LCMV) Armstrong strain selectively and persistently infects the majority of growth hormone (GH) producing cells in the anterior lobe of pituitary glands of C3H/St mice but negligibly infects GH producing cells of B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f04f204ec32947db56bb7f83844d7787
https://pubmed.ncbi.nlm.nih.gov/11222096
https://pubmed.ncbi.nlm.nih.gov/11222096
Autor:
M B, Oldstone, H, Lewicki, D, Thomas, A, Tishon, S, Dales, J, Patterson, M, Manchester, D, Homann, D, Naniche, A, Holz
Publikováno v:
Cell. 98(5)
Measles virus (MV) infects 40 million persons and kills one million per year primarily by suppressing the immune system and afflicting the central nervous system (CNS). The lack of a suitable small animal model has impeded progress of understanding h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dd1d486369e33e46baf5d91e9dfc8f28
https://pubmed.ncbi.nlm.nih.gov/10490102
https://pubmed.ncbi.nlm.nih.gov/10490102
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology. 79(2)
To recognize and respond immunologically to foreign antigens, T lymphocytes require the presentation of foreign peptides by MHC molecules. To determine which cells of the central nervous system (CNS) are capable of expressing MHC molecules, we used c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bdc3d866bc3bde6aea412c281734c3ec
https://pubmed.ncbi.nlm.nih.gov/10068211
https://pubmed.ncbi.nlm.nih.gov/10068211
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(9)
We tested the in vivo potential of a MHC class I-restricted blocking peptide to sufficiently lower an anti-viral CTL response for preventing virus-induced CTL-mediated autoimmune diabetes (insulin-dependent diabetes mellitus (IDDM)) in vivo without a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7af7dc7f71fc3acf94f66136da54898e
https://pubmed.ncbi.nlm.nih.gov/9794447
https://pubmed.ncbi.nlm.nih.gov/9794447