Zobrazeno 1 - 10
of 145
pro vyhledávání: '"M B, Martin"'
Autor:
Diana Zatreanu, Helen M. R. Robinson, Omar Alkhatib, Marie Boursier, Harry Finch, Lerin Geo, Diego Grande, Vera Grinkevich, Robert A. Heald, Sophie Langdon, Jayesh Majithiya, Claire McWhirter, Niall M. B. Martin, Shaun Moore, Joana Neves, Eeson Rajendra, Marco Ranzani, Theresia Schaedler, Martin Stockley, Kimberley Wiggins, Rachel Brough, Sandhya Sridhar, Aditi Gulati, Nan Shao, Luned M. Badder, Daniela Novo, Eleanor G. Knight, Rebecca Marlow, Syed Haider, Elsa Callen, Graeme Hewitt, Joost Schimmel, Remko Prevo, Christina Alli, Amanda Ferdinand, Cameron Bell, Peter Blencowe, Chris Bot, Mathew Calder, Mark Charles, Jayne Curry, Tennyson Ekwuru, Katherine Ewings, Wojciech Krajewski, Ellen MacDonald, Hollie McCarron, Leon Pang, Chris Pedder, Laurent Rigoreau, Martin Swarbrick, Ed Wheatley, Simon Willis, Ai Ching Wong, Andre Nussenzweig, Marcel Tijsterman, Andrew Tutt, Simon J. Boulton, Geoff S. Higgins, Stephen J. Pettitt, Graeme C. M. Smith, Christopher J. Lord
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Polθ has been recently identified as a therapeutic target in cancer but specific inhibitors are currently unavailable. Here, the authors identify small molecule inhibitors of Polθ’s polymerase activity which elicit BRCA1/2 synthetic lethality, en
Externí odkaz:
https://doaj.org/article/a5462d8522964b13a5f79a9e1b35250a
Autor:
Juliette Mangeney, T. Taniguchi, M.-B. Martin, Robson Ferreira, E. Riccardi, R. Kerjouan, M. Rosticher, Jérôme Tignon, Kenji Watanabe, P. Huang, Daniel Dolfi, A. Pierret, Pierre Seneor, Bruno Dlubak, S. S. Dhillon
Publikováno v:
Scopus-Elsevier
The use of geometrical constraints to induce synchrotron-like radiations represents an original concept for light emission in condensed matter [1] - [3] . Here, we show that corrugated graphene is a good candidate as a new type of room temperature co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039deb680306a3905b0b43b1c4bab70b
https://doi.org/10.1109/cleo/europe-eqec52157.2021.9542286
https://doi.org/10.1109/cleo/europe-eqec52157.2021.9542286
Autor:
Christina Alli, Christopher J. Lord, Marcel Tijsterman, Katherine Ewings, Marco Ranzani, Ai Ching Wong, Claire McWhirter, Martin Swarbrick, Harry Finch, Robert A. Heald, Rachel Brough, Nan Shao, Rebecca Marlow, Shaun Moore, Vera Grinkevich, Ellen Macdonald, Jayne Curry, Helen M. R. Robinson, Graeme Hewitt, Eleanor Knight, Christopher Bot, Syed Haider, Mathew Calder, Theresia A. Schaedler, Hollie McCarron, Luned M. Badder, Aditi Gulati, Martin Stockley, Eeson Rajendra, Sophie Langdon, Stephen J. Pettitt, Simon J. Boulton, Chris Pedder, Elsa Callen, Ed Wheatley, Wojciech Krajewski, André Nussenzweig, Daniela Novo, Peter Blencowe, Jayesh B. Majithiya, Laurent Rigoreau, Lerin Geo, Cameron Bell, Kimberley A. Wiggins, Diana Zatreanu, Geoff S. Higgins, Remko Prevo, Tennyson Ekwuru, Leon Pang, Simon N. Willis, Sandhya Sridhar, Marie Boursier, Diego Grande, Joana F. Neves, Mark Charles, Joost Schimmel, Andrew Tutt, Niall M. B. Martin, Omar Alkhatib, Amanda Ferdinand, Graeme C. M. Smith
Publikováno v:
Nature Communications, 12(1). NATURE RESEARCH
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
To identify approaches to target DNA repair vulnerabilities in cancer, we discovered nanomolar potent, selective, low molecular weight (MW), allosteric inhibitors of the polymerase function of DNA polymerase Polθ, including ART558. ART558 inhibits t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e50fa596497393cd588028cd95531690
https://hdl.handle.net/1887/3213877
https://hdl.handle.net/1887/3213877
Autor:
B. Quinard, F. Godel, M. Galbiati, V. Zatko, A. Sander, A. Vecchiola, S. Collin, K. Bouzehouane, F. Petroff, R. Mattana, M.-B. Martin, B. Dlubak, P. Seneor
Publikováno v:
Applied Physics Letters. 120:213503
We report on the growth of a ferromagnetic cobalt electrode by atomic layer deposition (ALD) and demonstrate it as a functional spin source in complete magnetic tunnel junctions (MTJs). Using an in situ protocol, we integrate a reference tunnel barri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::daf4debea0180e62bd2810d7bdb2eae4
https://doi.org/10.1063/5.0087869
https://doi.org/10.1063/5.0087869
Autor:
Diana A. Zatreanu, Helen M. R. Robinson, Omar Alkhatib, Marie Boursier, Harry Finch, Lerin Geo, Diego Grande, Vera Grinkevich, Robert Heald, Sophie Langdon, Jayesh Majithiya, Claire McWhirter, Niall M. B. Martin, Shaun Moore, Joana Neves, Eeson Rajendra, Marco Ranzani, Theresia Schaedler, Martin Stockley, Kimberley Wiggins, Rachel Brough, Sandhya Sridhar, Aditi Gulati, Nan Shao, Luned M Badder, Daniela Novo, Eleanor G. Knight, Rebecca Marlow, Syed Haider, Elsa Callen, Graeme Hewitt, Joost Schimmel, Remko Prevo, Christina Alli, Amanda Ferdinand, Cameron Bell, Peter Blencowe, Mathew Calder, Mark Charles, Jayne Curry, Tennyson Ekwuru, Katherine Ewings, Andre Nussenzweig, Marcel Tijsterman, Andrew Tutt, Simon J. Boulton, Geoff S. Higgins, Steve Pettitt, Graeme C. M. Smith, Christopher J. Lord
Publikováno v:
Molecular Cancer Therapeutics. 20:P056-P056
To target DNA repair vulnerabilities in cancer, we discovered nanomolar potent, selective, low molecular weight, allosteric inhibitors of the polymerase function of DNA polymerase Theta (Polθ), including ART558. ART558 inhibits the major Polθ-media
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c73bac7eb464761e2d542bd7b0cb26fd
https://doi.org/10.1158/1535-7163.targ-21-p056
https://doi.org/10.1158/1535-7163.targ-21-p056
Akademický článek
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Akademický článek
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Autor:
Q. Levesque, Frédéric Dumas-Bouchiat, André Pérennec, R. Boyer, M. Le Roy, Paul Laurent, Gérard Tanné, L. Divay, Damien Passerieux, Noham Martin, M-B. Martin, M. N. Sadiq, Aurelian Crunteanu
Publikováno v:
2019 IEEE MTT-S International Microwave Workshop Series on Advanced Materials and Processes for RF and THz Applications (IMWS-AMP).
Mott transition materials seem particularly promising to design reconfigurable devices. In this paper, Vanadium Dioxide (VO 2 ) is studied and characterized to design switches and elementary RF devices. The study shows experimentally promising RF per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5175dc3f23e4e0a4a0ec0d532191a091
https://doi.org/10.1109/imws-amp.2019.8880086
https://doi.org/10.1109/imws-amp.2019.8880086
Akademický článek
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Autor:
Niall M. B. Martin, Bastiaan Evers, Charlotte Knights, Janneke E. Jaspers, Jos Jonkers, Attilla Ting, Henry Brown, Keith W. Caldecott, Sven Rottenberg, Rajesh Odedra, Lenka Oplustil O'Connor, Robert Hugh Bradbury, Aaron Cranston, David Alan Rudge, Mark J. O'Connor, Marina Pajic, Louise J. Jones, Alan Lau, Stuart L. Rulten
Publikováno v:
Cancer Research. 76:6084-6094
The PARP inhibitor AZD2461 was developed as a next-generation agent following olaparib, the first PARP inhibitor approved for cancer therapy. In BRCA1-deficient mouse models, olaparib resistance predominantly involves overexpression of P-glycoprotein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::318c6f6c6cc972443af48c50dbf1283f
https://doi.org/10.1158/0008-5472.can-15-3240
https://doi.org/10.1158/0008-5472.can-15-3240