Zobrazeno 1 - 10
of 25
pro vyhledávání: '"M B, Graeber"'
Publikováno v:
Pharmacopsychiatry. 48
Publikováno v:
Neurogenetics. 2:0227-0230
Autor:
U. Müller, M. B. Graeber
Publikováno v:
Journal of Molecular Medicine. 74:71-84
A neurogenetic disorder is defined as a clinical disease caused by a defect in one or more genes which affect the differentiation and function of the neuroectoderm and its derivatives. Genetic findings in various neurogenetic disorders are discussed.
Autor:
H, Slodzinski, L B, Moran, G J, Michael, B, Wang, S, Novoselov, M E, Cheetham, R K B, Pearce, M B, Graeber
Publikováno v:
Clinical neuropathology. 28(5)
Recent studies highlight the role of endoplasmic reticulum (ER) stress and aberrant protein degradation in the pathogenesis of neurodegenerative disorders. Herp which is encoded by the HERPUD 1 (homocysteine-inducible, endoplasmic reticulum stress-in
Publikováno v:
Journal of neurocytology. 30(6)
The discovery that missense mutations in the alpha-synuclein gene represent a rare genetic cause of Parkinson's disease (PD) has had significant impact on the development of research into neurodegenerative disorders. It is becoming increasingly clear
Publikováno v:
Journal of neuroscience research. 66(1)
Macrophages in the brain can have a triple source. They may originate from recently blood-derived precursors, from the largely resident perivascular cell population (perivascular macrophages and related cells), and from intrinsic parenchymal as well
Autor:
Thomas B. Crotty, Jan C. Buckner, Gary L. Keeney, S. Bauserman, Johan M. Kros, H. D. Tazelaar, Caterina Giannini, Bernd W. Scheithauer, James Burton, Antonio G. Nascimento, H. Altermatt, M. B. Graeber, Amy L. Weaver, Peter C. Burger, R. Riepe, P. Pernicone, Sverre Mørk
Publikováno v:
Journal of Neuropathology and Experimental Neurology, 60(3), 248-262. Oxford University Press
Prognostic value of histological grading of oligodendroglial tumors is controversial and interobserver reproducibility in grading of these tumors is unknown. Seven neuropathologists and 6 surgical pathologists experienced in brain tumor-diagnosis ass
Publikováno v:
Biological Chemistry. 380
The cause of the selective degeneration of nigrostriatal neurons in Parkinson disease (PD) has remained largely unknown. Exceptions include rare missense mutations in the alpha-synuclein gene on chromosome 4, a potentially pathogenic mutation affecti
Publikováno v:
Journal of neurocytology. 26(11)
Brain lesions, even of the most subtle type, are accompanied by the activation of microglia, the main immune cells of the brain. Microglial cells dramatically increase in number through proliferation and adhere to the injured neurons, where they disp
Publikováno v:
Neuropathology and applied neurobiology. 23(4)
Alzheimer's and Parkinson's diseases (AD, PD) are among the most common neurodegenerative disorders in adults. Both AD and PD have a complex aetiology, and it is widely considered that genetic factors, acting independently or in concert with other ge