Zobrazeno 1 - 10
of 26
pro vyhledávání: '"M B, Goldring"'
Publikováno v:
Journal of biological regulators and homeostatic agents. 29
The exact mechanisms controlling the development and progression of osteoarthritis have not yet been clarified. Our aim was to investigate new pathomechanisms, with an emphasis on novel molecular targets that might regulate human chondrocytes in oste
Autor:
J R, Robbins, M B, Goldring
Publikováno v:
Methods in molecular medicine. 18
The chondrocyte is responsible for synthesis of cartilage matrix proteins, and, thereby, the specialized mechanical properties of articular cartilage, including tensile strength and resistence to mechanical loading (1). The limited repair response by
Autor:
M B, Goldring
Publikováno v:
Methods in molecular medicine. 2
Chondrocytes comprise the single cellular component of adult hyaline cartilage and are considered to be terminally differentiated cells that maintain the cartilage matrix when turnover is low. The major components of the extracellular matrix synthesi
Autor:
S R, Goldring, M B, Goldring
Publikováno v:
Journal of musculoskeletalneuronal interactions. 6(4)
Autor:
M B, Goldring
Publikováno v:
Journal of musculoskeletalneuronal interactions. 2(6)
Publikováno v:
Arthritis and rheumatism. 48(12)
Because the immortalized chondrocyte cell lines C-28/I2, T/C-28a2, and T/C-28a4 have become a common tool in cartilage research, permitting investigations in a largely unlimited and standardized manner, we investigated the molecular phenotype of thes
Publikováno v:
Biorheology. 39(1-2)
This work was performed to determine whether one aspect of load, pressure, could alter tumour necrosis factor (TNF) receptor type I (RI) expression on chondrocytes. Encapsulated tsT/AC62, osteoarthritic (OA) or non-arthritic (NA) chondrocytes were ce
Publikováno v:
Molecular medicine (Cambridge, Mass.). 6(8)
BACKGROUND: Tissues undergoing a chronic inflammatory process, such as the synovium in rheumatoid arthritis, are characterized by the infiltration of lymphocytes of different subsets and activation of monocyte/macrophages. Interleukin-1 (IL-1), a mon
Publikováno v:
Arthritis and rheumatism. 43(10)
To develop a reproducible immortalized human chondrocyte culture model for studying the regulation of chondrocyte functions relevant to arthritic diseases in adult humans.Primary adult articular chondrocytes were immortalized with a retrovirus expres
Autor:
M B, Goldring
Publikováno v:
Arthritis and rheumatism. 43(9)