Zobrazeno 1 - 10
of 236
pro vyhledávání: '"M B, Covington"'
Publikováno v:
The Journal of Immunology. 159:4524-4531
Human monocytes rapidly produce TNF-alpha following activation by bacterial LPS. The message for TNF-alpha encodes a 26-kDa protein that is proteolytically processed to the secreted 17-kDa form. Sequencing of the N terminus of the protein secreted by
Publikováno v:
Annals of the rheumatic diseases. 60
Studies conducted over the past decade have demonstrated a central role for tumour necrosis factor alpha (TNFalpha) in inflammatory diseases. As a result of this work, a number of biological agents that neutralise the activity of this cytokine have e
Autor:
W, Yao, Z R, Wasserman, M, Chao, G, Reddy, E, Shi, R Q, Liu, M B, Covington, E C, Arner, M A, Pratta, M, Tortorella, R L, Magolda, R, Newton, M, Qian, M D, Ribadeneira, D, Christ, R R, Wexler, C P, Decicco
Publikováno v:
Journal of medicinal chemistry. 44(21)
A pharmacophore model of the P1' site, specific for aggrecanase, was defined using the specificity studies of the matrix metalloproteinases and the similar biological activity of aggrecanase and MMP-8. Incorporation of the side chain of a tyrosine re
Autor:
P A, Scherle, E A, Jones, M F, Favata, A J, Daulerio, M B, Covington, S A, Nurnberg, R L, Magolda, J M, Trzaskos
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(10)
Activation of the extracellular signal-regulated kinase (ERK) pathway has been shown to occur in monocytes following stimulation with LPS. However, the importance of this event for monocyte function is not clear. To address this issue, we used the no
Autor:
Zhang, Yuquan, Li, Yan
Publikováno v:
New Journal of Chemistry; 11/7/2024, Vol. 48 Issue 41, p17915-17927, 13p
Publikováno v:
RSC Medicinal Chemistry; Jun2024, Vol. 15 Issue 6, p1798-1827, 30p
Autor:
Manna, Susanta Kumar1 (AUTHOR), Giri, Soumen2 (AUTHOR) giri.soumen02@gmail.com, Mondal, Sampa1 (AUTHOR), Sana, Rabindra Nath1 (AUTHOR), Samal, Aroop Kumar2 (AUTHOR), Mandal, Arabinda1 (AUTHOR)
Publikováno v:
ChemistrySelect. 1/9/2023, Vol. 8 Issue 1, p1-32. 32p.
Autor:
Semghouli, Anas1,2 (AUTHOR), Remete, Attila M.1 (AUTHOR) remete.attila.mario@szte.hu, Kiss, Loránd2 (AUTHOR) kiss.lorand@ttk.hu
Publikováno v:
ChemistrySelect. 12/13/2022, Vol. 7 Issue 46, p1-9. 9p.
Publikováno v:
Chemical Communications; 4/14/2024, Vol. 60 Issue 29, p3958-3961, 4p
Autor:
Stepannikova, Kateryna O.1 (AUTHOR), Vashchenko, Bohdan V.1,2 (AUTHOR), Grygorenko, Oleksandr O.1,2 (AUTHOR), Gorichko, Marian V.2 (AUTHOR), Cherepakha, Artem Yu.1 (AUTHOR), Moroz, Yurii S.2,3 (AUTHOR), Volovenko, Yulian M.2 (AUTHOR), Zhersh, Serhii1,2 (AUTHOR) zhersh@ukr.net
Publikováno v:
European Journal of Organic Chemistry. 12/21/2021, Vol. 2021 Issue 47, p6530-6540. 11p.