Zobrazeno 1 - 10
of 1 588
pro vyhledávání: '"M Aitken"'
Autor:
Tomoka Gose, Heather M. Aitken, Yao Wang, John Lynch, Evadnie Rampersaud, Yu Fukuda, Medb Wills, Stefanie A. Baril, Robert C. Ford, Anang Shelat, Megan L. O’Mara, John D. Schuetz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/71a9b8622126468d8a9b749d61a64ec6
Autor:
Bronagh Blackwood, Matt P Wise, Kalliopi Kydonaki, Nazir I Lone, Timothy S Walsh, Christopher J Weir, Benedict Creagh-Brown, Michael C Reade, Lydia M Emerson, Leanne M Aitken, Cathrine A McKenzie
Publikováno v:
BMJ Open, Vol 14, Iss 4 (2024)
Introduction An association between deep sedation and adverse short-term outcomes has been demonstrated although this evidence has been inconsistent. The A2B (alpha-2 agonists for sedation in critical care) sedation trial is designed to determine whe
Externí odkaz:
https://doaj.org/article/7a01bb1c8b5844ff8bd2b7e8e36df0b2
Autor:
Julia Krause, Alexander Nickel, Alexandra Madsen, Hamish M. Aitken-Buck, A. M. Stella Stoter, Jessica Schrapers, Francisco Ojeda, Kira Geiger, Melanie Kern, Michael Kohlhaas, Edoardo Bertero, Patrick Hofmockel, Florian Hübner, Ines Assum, Matthias Heinig, Christian Müller, Arne Hansen, Tobias Krause, Deung-Dae Park, Steffen Just, Dylan Aïssi, Daniela Börnigen, Diana Lindner, Nele Friedrich, Khaled Alhussini, Constanze Bening, Renate B. Schnabel, Mahir Karakas, Licia Iacoviello, Veikko Salomaa, Allan Linneberg, Hugh Tunstall-Pedoe, Kari Kuulasmaa, Paulus Kirchhof, Stefan Blankenberg, Torsten Christ, Thomas Eschenhagen, Regis R. Lamberts, Christoph Maack, Justus Stenzig, Tanja Zeller
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-16 (2023)
Abstract Background Long-chain acyl-carnitines (ACs) are potential arrhythmogenic metabolites. Their role in atrial fibrillation (AF) remains incompletely understood. Using a systems medicine approach, we assessed the contribution of C18:1AC to AF by
Externí odkaz:
https://doaj.org/article/8c183ecc7563479ba469a156b176a394
Autor:
Tomoka Gose, Heather M. Aitken, Yao Wang, John Lynch, Evadnie Rampersaud, Yu Fukuda, Medb Wills, Stefanie A. Baril, Robert C. Ford, Anang Shelat, Megan L. O’Mara, John D. Schuetz
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract ABCG2 is a medically important ATP-binding cassette transporter with crucial roles in the absorption and distribution of chemically-diverse toxins and drugs, reducing the cellular accumulation of chemotherapeutic drugs to facilitate multidru
Externí odkaz:
https://doaj.org/article/0de3acd6f4884042a8d4c3ec9400e788
Autor:
John Norrie, Stephen Morris, Daniel Francis McAuley, Bronagh Blackwood, Paul Dark, Matt P Wise, Anthony C Gordon, Kalliopi Kydonaki, Timothy Simon Walsh, David Hope, Christopher Weir, Gavin Perkins, Nazir I Lone, Benedict Creagh-Brown, Julia Boyd, Michael Reade, Richard Anthony Parker, Leanne M Aitken, Valerie J Page, Alasdair MacLullich, Cathrine A McKenzie, Alix Macdonald, Annabel Giddings, Lydia Emerson, Robert Glen
Publikováno v:
BMJ Open, Vol 13, Iss 12 (2023)
Introduction Almost all patients receiving mechanical ventilation (MV) in intensive care units (ICUs) require analgesia and sedation. The most widely used sedative drug is propofol, but there is uncertainty whether alpha2-agonists are superior. The a
Externí odkaz:
https://doaj.org/article/ca882e250b3f4906a633eda573496be4
Autor:
Helen M. M. Waddell, Matthew K. Moore, Morgan A. Herbert-Olsen, Martin K. Stiles, Rexson D. Tse, Sean Coffey, Regis R. Lamberts, Hamish M. Aitken-Buck
Publikováno v:
Adipocyte, Vol 11, Iss 1, Pp 325-334 (2022)
Predictors of overall epicardial adipose tissue deposition have been found to vary between males and females. Whether similar sex differences exist in epicardial fat cell morphology is currently unknown. This study aimed to determine whether epicardi
Externí odkaz:
https://doaj.org/article/8e22d605723a49a89193f7437e2bc3dd
Publikováno v:
Antibiotics, Vol 13, Iss 2, p 158 (2024)
Mycobacterium avium ssp. paratuberculosis (MAP) is the cause of Johne’s disease (JD), which is a chronic infectious gastrointestinal disease of ruminants and is often fatal. In humans, MAP has been associated with Crohn’s disease (CD) for over a
Externí odkaz:
https://doaj.org/article/81570d039c6c4a69aaa1fc9e35a3d8aa
Publikováno v:
BMC Health Services Research, Vol 22, Iss 1, Pp 1-17 (2022)
Abstract Background Patients who deteriorate in hospital wards without appropriate recognition and/or response are at risk of increased morbidity and mortality. Track-and-trigger tools have been implemented internationally prompting healthcare practi
Externí odkaz:
https://doaj.org/article/3ed237ca70c742b7afbc08866aea83b7
Autor:
Alan J. Mouton, Nikaela M. Aitken, Sydney P. Moak, Jussara M. do Carmo, Alexandre A. da Silva, Ana C. M. Omoto, Xuan Li, Zhen Wang, Alexandra C. Schrimpe-Rutledge, Simona G. Codreanu, Stacy D. Sherrod, John A. McLean, John E. Hall
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
IntroductionMetabolic reprogramming from glycolysis to the mitochondrial tricarboxylic acid (TCA) cycle and oxidative phosphorylation may mediate macrophage polarization from the pro-inflammatory M1 to the anti-inflammatory M2 phenotype. We hypothesi
Externí odkaz:
https://doaj.org/article/5ddb9397e379446ebc06b0ae59b7d981
Publikováno v:
Health and Quality of Life Outcomes, Vol 20, Iss 1, Pp 1-12 (2022)
Abstract Background Health-related quality of life (HRQoL) is important in determining surgical success, particularly from the patients’ perspective. Aims To identify predictors for HRQoL outcome after cardiac surgery in order to identify potential
Externí odkaz:
https://doaj.org/article/dfa234bb019142909ffe15866742aab1