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Male and Female Mice Exhibit Divergent Responses of the Cortical Vasculature to Traumatic Brain Injury

Autor: William J. Pearce, Bethann M. Affeldt, John H. Zhang, Angela Avitua, Isabelle Enjalric, Mark Walsworth, Andre Obenaus, Arjang Salehi, Elizabeth Haddad, Jiping Tang, Mary Hamer, Mohsen Baghchechi, Amandine Jullienne, Sonali Bhakta

Publikováno v: Journal of neurotrauma, vol 35, iss 14

We previously reported that traumatic brain injuries (TBI) alter the cerebrovasculature near the injury site in rats, followed by revascularization over a 2-week period. Here, we tested our hypothesis that male and female adult mice have differential

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c35aeef68e663361715c523ace2218c0
https://doi.org/10.1089/neu.2017.5547

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Repeated Pediatric Concussions Evoke Long-Term Oligodendrocyte and White Matter Microstructural Dysregulation Distant from the Injury

Autor: Jeff Dunn, Jeong Bin Lee, Andrea C. Pardo, Andre Obenaus, Mary Hamer, Yaritxa Gamboa, Bethann M. Affeldt

Publikováno v: Developmental Neuroscience. 40:358-375

Concussion or mild traumatic brain injury (mTBI) is often accompanied by long-term behavioral and neuropsychological deficits. Emerging data suggest that these deficits can be exacerbated following repeated injuries. However, despite the overwhelming

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62dd37fc4d335a8973d05fa0413b57ed
https://doi.org/10.1159/000494134

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Corpus Callosum Vasculature Predicts White Matter Microstructure Abnormalities after Pediatric Mild Traumatic Brain Injury

Autor: Bethann M. Affeldt, Jeong Bin Lee, Indira S. Harahap-Carrillo, Andre Obenaus, Mary Hamer, Kara M. Wendel, Andrea C. Pardo

Publikováno v: Journal of neurotrauma.

Emerging data suggest that pediatric traumatic brain injury (TBI) is associated with impaired developmental plasticity and poorer neuropsychological outcomes than adults with similar head injuries. Unlike adult mild TBI (mTBI), the effects of mTBI on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::172fa3b3437cc604ae6c3ad0a88e9433
https://pubmed.ncbi.nlm.nih.gov/29739276

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Region specific oligodendrocyte transcription factor expression in a model of neonatal hypoxic injury

Autor: Jonathan Chan, Bethann M. Affeldt, Andrea C. Pardo, Andre Obenaus

Publikováno v: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 61

White matter injury (WMI) of prematurity is associated with a spectrum of neurological disorders ranging from mild cognitive and behavioral deficits to cerebral palsy. Translational studies have implicated impaired oligodendrocyte development after h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e17417f52e8a411b259996aa90a763c2
https://pubmed.ncbi.nlm.nih.gov/28546087

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Phänotypische Charakterisierung von primärkultivierten Tumorstroma-Assoziierten Myofibroblasten bei Kolorektalen Lebermetastasen

Autor: D. C. Bröring, S Herbst, Xavier Rogiers, L. Müller, Philip Kahl, F Goumas, M Affeldt

Publikováno v: Deutsche Gesellschaft für Chirurgie ISBN: 9783540200277
121. Kongress der Deutschen Gesellschaft für Chirurgie; 20040427-20040430; Berlin; DOC04dgch0847 /20041007/

Myofibroblasts, a mesenchymal cell type in hepatic parenchyma, have unique features with respect to their cellular origin, morphology and function. Myofibroblasts play an important role in pathological conditions such as liver fibrosis, cirrhosis and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc5f2f7ac5ccad8eae4ae7df738d02dc
https://doi.org/10.1007/978-3-642-18547-2_33

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Functional characterization of atherosclerosis-associated Ser128Arg and Leu554Phe E-selectin mutations

Autor: Astrid Speer, G. Baumann, Stephan B. Felix, C. Gläser, A. Scheer, M. Moobed, M. Affeldt, Renate Stahn, Katrin Wenzel, K. Denner

Publikováno v: Biological chemistry. 380(6)

The cellular adhesion molecule E-selectin is expressed on activated endothelial cells, and is involved in the process of adherence of blood cells to vessel endothelium in inflammatory events such as atherosclerosis. In a recent study we found a Ser12

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04c44f2624865af49830f3fd3deca604
https://pubmed.ncbi.nlm.nih.gov/10430030

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Relationship of polymorphisms in the renin-angiotensin system and in E-selectin of patients with early severe coronary heart disease

Autor: M. Ernst, C. Gläser, Katrin Wenzel, R. Hanke, K. Rohde, Stephan B. Felix, A. Blackburn, Astrid Speer, M. Affeldt, F. X. Kleber, Gert Baumann

Publikováno v: Journal of molecular medicine (Berlin, Germany). 75(1)

Previous association studies between angiotensin-converting enzyme (ACE) and angiotensinogen (AGT) polymorphisms and several cardiovascular diseases have reported variable results. Therefore we examined the association of the DNA variants of ACE and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8138df012d4fc7c6692882048f151911
https://pubmed.ncbi.nlm.nih.gov/9020385

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